Eoghan Harrington

Current: Oxford Nanopore, Previous: Flatiron Health, 23andMe, Stanford, EMBL, TCD. Opinions my own

[Chris Seymour @iiSeymour]

Now, @nanopore only approaches are producing the best t2t automated assemblies ever produced with 30 contigs and 5 scaffolds! 🤯🤯🤯🤯 #nanoporeconf

[Oxford Nanopore @nanopore]

What if you could characterise brain tumours in hours, rather than weeks? And in doing so allow neurosurgeons to adjust their surgical strategies on the spot.

Here, researchers showed that they were able to do just that by leveraging nanopore technology: https://t.co/gicIpZPm7G

[Philipp Rescheneder @philres1]

Come and work with us! It's an amazing team and an incredible opportunity to develop computation tools that will have real world impact in a wide range of areas as well as being part of pushing the boundaries of what is possible with DNA and RNA sequencing.

[Sergey Nurk 🇺🇦 @sergeynurk]

Two more openings in our applications development team. Come help us build new computational methods and software to fully leverage the tremendous recent improvements in @nanopore sequencing!
https://t.co/0KJellFccY

[Dan Landau @landau_lab]

✂️Splice splice baby!✂️

New paper just out in @CellStemCell integrating @nanopore long read single-cell isoform mapping into our broader genotype-phenotype vision for clonal mosaicism !
https://t.co/2VmlsWiOGG

[Oxford Nanopore @nanopore]

Here @BanfieldLab used #nanopore sequencing to study 'the nature and existence of enigmatic genetic elements' (Borgs) in soil. They assembled 7 new curated Borg genomes, revealing extensive DNA methylation that differentiates them from their host archaea, Methanoperedens. 🧵1/2

[Matthew Parker @bioinfomatt]

Another LOADED update from the @nanopore EPI2ME team with wf-metagenomics and wf-somatic-variation getting new functionality & our desktop app getting easier for Windows users & displaying workflow progress. All this and more here: https://t.co/hY75WcHOxH

We’re also hiring…

[John Beaulaurier @bowerlauwer]

Bacterial epigenomes are very cool and extremely diverse! And you get them for free when you do @nanopore sequencing 🧫🧬

[Christine He @christine_y_he]

Come talk 🦠💻🧬 with me at #ASMicrobe! I'll be:
1. At my poster: adaptive sampling, MAGs, and host methylome from human microbiomes (Sat, HMB06)
2. Intro-ing metagenomics pipelines for Nanopore data (Sat/Sun, Data for Breakfast, 10:05-10:20 @ booth 2207)
3. At the Nanopore booth

[John Beaulaurier @bowerlauwer]

#ASMicrobe folks: come see @christine_y_he at her poster to learn how @nanopore sequencing of human microbiome samples can simultaneously:

- Deplete host DNA to get more microbial reads
- Generate genome-resolved assemblies
- Provide host DNA methylation from the proximal tissue

[Martin Smith @martinalexsmith]

47,000 nanopore genomes processed a year (84k so far).

[Oxford Nanopore @nanopore]

New addition to the Oxford Nanopore Open Datasets: Genome in a Bottle Ashkenazi Trio, accessible via @AWSCloud.

Sequencing was performed using #PromethION Flow Cells, (~200Gb yield each), Kit V14 chemistry & analysis driven by @nextflowio.

Read here: https://t.co/qw7Sg4OIqR

[Eoghan Harrington @eoghh]

This should save me some time

[Rob Mac @RMcElhenney]

Incoming…

[Rob Mac @RMcElhenney]

Incoming…

[Joseph @JosephGuhlin]

Minimap2 #Rust bindings update to v0.1.11.

HTS lib support (SAM/BAM writing) and mm2-fast support via feature flag.

Huge thanks to @eoghh for the HTS lib support!

Check out the full announcement:
https://t.co/l1vI9xPSvQ

#bioinformatics #nanopore #genomics

[Pedro Beltrao @pedrobeltrao]

Blog post - 20 years of open science or how we haven't radically changed the way we do science online. Thoughts on how we don't seem to be using the internet to its fullest potential in scientific collaborations https://t.co/aICVu5NjS4

[Mikko Taipale @mike_tilapia]

Come and join us – awesome community, great resources, and a cool city! Besides, in this crazy world is there a better place to be than Canada? 🇨🇦

[Lappalainen Lab @tuuliel_lab]

Excited to share our paper, out today in @Nature, where we characterize transcriptome variation in human tissues by long-read sequencing. Huge thanks to @g_dafni @beryl_bbc Garrett Garborcauskas @dgmacarthur and other collaborators. 🧵
https://t.co/NbQuy0cJWF

[Rocío Esteban - ONT @bio_rococo]

Really happy to see RRMS out! I'm sure will enable a bunch of new applications in epigenetics 🧬 Check out all the advantages of this adaptive sampling method for cost-effective methylation calling using #nanopore technology !
Spoiler: lots!

[Marcus Stoiber @Stoibs11]

Looking for a motivated person to join my #Algorithms and #MachineLearning team to further improve our industry leading @nanopore modified base detection capabilities!