Fan Zheng

Induced Proximity | Molecule AI | Systems biology. Views are my own.

[Erick Erickson @EWErickson]

The fact Anthropic thought it could convince Christian theologians that its programmers could create a machine with a soul is the only story you need to hear to know to avoid the IPO.

[Fan Zheng @fan_compbio]

the rate of spot instance termination is way higher than like 1 yr ago😡

[Fan Zheng @fan_compbio]

Why did Uniprot stop linking to RCSB pdb?

[Fan Zheng @fan_compbio]

I’m glad my Mac caught it—and that I was paying enough attention to deny every access request. No, I am not supposed to write an instruction in AGENTS.md to prevent this behavior.

[Fan Zheng @fan_compbio]

I dislike the GPT-5.6 update. I started agentic coding earlier this year, when GPT-5.4 was out—late adopter, I know. I chose Codex over Claude Code because of my concerned about Claude’s faster token consumption. I genuinely enjoyed the product, especially its VS Code plugin.

[Fan Zheng @fan_compbio]

The other day, Codex tried to control my home directory for a simple question about DepMap. I was only testing, fully aware of its limitation without direct access to the data. Embarrassed, Codex decided it wanted to scan my entire home directory in search of a non-existing table

[Fan Zheng @fan_compbio]

AI models cannot be truly useful without access to the internet though. But if internet searches are their only external communications, the risk is significantly lower.

[Fan Zheng @fan_compbio]

Anthropic’s growing presence in the pharmaceutical and biotech industries raises major concerns about conflicts of interest. Organizations must now strike a delicate balance between protecting proprietary data and realizing the productivity gains of AI adoption

[Anthropic @AnthropicAI]

We're offering grants of up to $50,000 in Claude usage credits to researchers accelerating cures for rare diseases.

This is our first focused call within AI for Science, our program supporting scientists using Claude to speed up discovery. https://t.co/rZEmwh07cd

[Fan Zheng @fan_compbio]

Two commonly discussed paths:
1. Use established data platforms with strong security track records, ensuring that AI operates within well-defined governance boundaries.
2. Host open-source models on private infrastructure, keeping AI-related data and traffic entirely in-house.

[GAMA Miguel Angel 🐦‍⬛🔑 @miangoar]

Here is my biggest contribution to #science so far. A short series of memes inspired by #AlphaFold3 from @GoogleDeepMind

1/9🧵

[Fan Zheng @fan_compbio]

Today's best #recomb2024

[Fan Zheng @fan_compbio]

Can't ask for too much from a guest Wifi, but the one in MIT is still surprisingly bad

[Fan Zheng @fan_compbio]

We tend to think the path we didn't take would be harder. My friend got a faculty position, and I asked if they ever considered industry. They said yes but it seemed too difficult. Well, I thought getting a faculty position would be darn harder!

[Fan Zheng @fan_compbio]

These company names are like joke. Just want to say Neomorph is a really good name. #FierceMadness: The Best Biotech Name Tournament—Round of 32 RESULTS https://t.co/guj9VbvGYf

[Fan Zheng @fan_compbio]

I didn't accomplish more earlier my career largely because of not being a sudoer

[Fan Zheng @fan_compbio]

In my academic years ISMB seemed to be a more interesting conference than RECOMB; now it feels the other way.

[Fan Zheng @fan_compbio]

Neomorph Announces Multi-Target Collaboration with Novo Nordisk to Discover Novel Molecular Glue Degraders for Car... https://t.co/BC7R8dlX7e

[Elizabeth McKenna @ElizSMcKenna]

Now online in @CD_AACR: Cancer Mutations Converge on a Collection of Protein Assemblies to Predict Resistance to Replication Stress - by @Xiaoyu_SysBio @aksinghal90 @TreyIdeker and colleagues https://t.co/gAw1xSwDri @UCSanDiego @UCSDCancer #MachineLearning