Check out our latest work! Congratulations to Yuanming, Hanzhi @Hzhzhzwrwrwr , Franco, @landau_lab, and everyone for their hard work! m6A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment: Cell Reports https://t.co/NGaDW8QP14
Mutations in a gene called FOXA1 are responsible for a distinct class of prostate cancer tumors, MSK researchers have found. @nature @CharlesSawyers https://t.co/mUH3MREQpn
RT and help congratulate the @pewtrusts 2019 scholars & fellows!
We’re proud to announce that our own John Maciejowski and Piro Lito are part of this distinguished program dedicated to advancing human health through cutting-edge research.
Hey folks - I got news that might seem not surprising to many of you. But @toddgolub1@gaddyg & @meyersonlab just established it beyond reasonable doubt.
Your MCF7 looks genetically nothing like & behaves totally differently in HTS studies from my MCF7.
https://t.co/jvHNbWQAae
Large scale genetic interactions in human with double CRISPRi (472×472 genes x2 cell lines). Besides basic biology findings this has useful applications for design of drug targets in cancer (second hit for LoF) https://t.co/r6fLeNcHx3
Researchers, including HHMI Investigator Arul Chinnaiyan, have identified a gene that could be a key target for future prostate cancer therapies. https://t.co/Dgr2hHFf94
New Review from Kester and van Oudenaarden "Single-Cell Transcriptomics Meets Lineage Tracing" covers lineage trajectory prediction algorithms, single-cell genetic lineage tracing, and the combination of these techniques in #stemcell and cancer research. https://t.co/r9rKaWRmie
Our latest results from @IcrLordLab - a series of CRISPR screens to investigate PARP inhibitor resistance. We used some tricks to enrich for in-frame mutations - more interesting than knockouts! Suprisingly, some BRCA1 mutant lines can tolerate PARP1 loss. https://t.co/jEZqHYMnA6
Epic paper from Halazonetis lab in @Nature: Intragenic origins due to short G1 phases underlie oncogene-induced DNA replication stress https://t.co/Lg0z4NzclG
From @eLife and authored by HHMI Investigator Charles Sawyers and colleagues, an important message about the validation of therapeutic targets in cancer. https://t.co/iWH0cVAx35
The "Reproducibility Tools & Resources" handout and our Caltech workshop slides are now up. https://t.co/w6qSFPeW2d (workshop co-organized by @CodeOceanHQ@Addgene@ProtocolsIO)
NICHE-seq combines combines photoactivatable fluorescent proteins and single-cell RNA-seq to molecularly characterize cell types identified by microscopy in various tissues. https://t.co/GqAtOq7iVk #NBThighlight