Michael Kharas MSK

Michael Kharas PhD is a Member in Molecular Pharmacology at the Sloan Kettering Institute. Tweets are my views alone not MSKCC.

[Vijay Sankaran @bloodgenes]

🚨 Excited to share a new paper in Cell! Human genetics led us to HOTSCRAMBL, a HOXA-locus lncRNA that regulates 🩸#stemcell self-renewal and HOXA9 splicing, with implications for AML.

Amazing work by @lvchosen1 with @silvirouskin, @Armstrong_dfci, and many more!

https://t.co/Kralk3tmzg

[Abdel-Wahab Lab @AbdelWahablab]

Excited to announce a new paper out now in @CD_AACR on a unique CAR T cell platform that eliminates AML and B-ALL without harming vital endogenous immune cells or other normal human tissues:
https://t.co/IVb5KIYqMs

[Michael Kharas MSK @KharasLab]

@leonard_zon Congrats to George! It’s the dynamic duo! Always great to see you together! Cheers!

[Michael Kharas MSK @KharasLab]

@WSJ Amazing news! Congrats to Ross and Team!

[The Wall Street Journal @WSJ]

Eli Lilly continued its recent buying spree, agreeing to pay up to $2.3 billion for Ajax Therapeutics in a deal that bolsters the drugmaker’s blood-cancer portfolio. https://t.co/0G3YkcilV8

[Michael Kharas MSK @KharasLab]

@Gritsman_lab @SteidlUli Congrats!!!!!

[Michael Kharas MSK @KharasLab]

@landau_lab @CD_AACR Congrats!

[Michael Kharas MSK @KharasLab]

@chartnote @leonard_zon Congrats!

[Michael Kharas MSK @KharasLab]

@AbdelWahablab @natgenet @KellyLBolton @WashU @IrenaeusChan @PuZhang09980432 Congrats!!!

[Michael Kharas MSK @KharasLab]

@iannisaifantis1 @landau_lab @nyugrossman Congrats! Always impressed with your leadership! Cheers!

[Michael Kharas MSK @KharasLab]

@Dan_A_Heller Congrats!

[Daniel Heller @Dan_A_Heller]

On the cover of this month's issue of Nature Nanotechnology! Our nanosensor + AI-based liquid biopsy (blood test) for brain tumors that also enables the discovery of new biomarkers. https://t.co/AnhR4rXzNV

[Michael Kharas MSK @KharasLab]

Hello everyone! We're participating in @Cycle4Survival to raise money for rare cancer research at @MSKCancerCenter, and your support would mean so much to us. Make a 100% tax-deductible donation using the link. Thank you! https://t.co/zXL2FSuCCh

[Kentsis Research Group @KentsisResearch]

Researchers @MSKCancerCenter @WeillCornell Discover PGBD5 Guides Normal Brain Development in Addition to Causing Cancers https://t.co/T5cR3P9jTF

[Michael Kharas MSK @KharasLab]

@ScienceAdvances @KentsisResearch Congrats Alex!! Amazing to see this story out!! Love the cover!!!

[Science Advances @ScienceAdvances]

Researchers identify PGBD5, a transposase-derived gene, as an essential regulator of normal brain development in mice and humans.

Learn more in this week’s issue of Science Advances: https://t.co/LmcIk3JCKX

[Michael Kharas MSK @KharasLab]

@dstarczynowski @bloodgenes @GauravA_UK @ScienceMagazine @broadinstitute @hhmi_science @BostonChildrens @DanaFarberNews @DanaFarber Thanks!!

[Eric Topol @EricTopol]

People with TP53 mutations have blood stem cell clones (CHIP) which promote chronic inflammation, aging, and risk of blood cancers. This can be blocked by multiple means (as shown below) to potentially prevent cancer, but CHIP is not assayed in the clinic.
https://t.co/5W7JeQjia7 @jclinicalinvest

[Memorial Sloan Kettering Cancer Center @MSKCancerCenter]

Scientists have known for decades that there are gene mutations that increase your risk of developing cancer. But there is also a genetic variant that could reduce the risk of developing certain #bloodcancers, according to new research co-led by scientists from MSK.

“We’ve discovered the mechanism by which a change within the MUSASHI2 (MSI2) gene region appears to protect people from blood cancers related to clonal hematopoiesis,” says cancer biologist @KharasLab, a member of the Molecular Pharmacology Program in the Sloan Kettering Institute and co-corresponding author of the paper. 

Learn more: https://t.co/PCrJeKIoGY

[Michael Kharas MSK @KharasLab]

@LeeGrimesLab @GauravA_UK @bloodgenes @_ruslansoldatov @AbdelWahablab @AlexBickMDPhD Thanks so much Lee!!!

[Michael Kharas MSK @KharasLab]

Check out our latest story https://t.co/7wLiJlYDyy! Huge thanks to @GauravA_UK and the @bloodgenes lab for driving this work forward together with us. This was a great team effort with outstanding collaborators @_ruslansoldatov, @AbdelWahablab, and @AlexBickMDPhD.