@davideyoungmd@DrPatrick Interleukin-2 and Interleukin-15
Shared receptor biology
Both signal through:
•CD122 (IL-2/15Rβ)
•CD132 (common γ chain)
But they differ in the alpha receptor:
•IL-2 → IL-2Rα (CD25)
•IL-15 → IL-15Rα
\mathrm{IL\text{-}2}\rightarrow
@DrMakaryFDA ALC is a significant number with lower levels being tied to poor outcomes and higher rates tied to better outcomes.
Ibrx has RMAT status
Let patients and Dr.’s chose
@DrMakaryFDA@DrOzCMS@DrPatrick
People are dying and you can do something about it. Start with the science and the Hippocratic oath.
If you’re not part of the solution you’re part of the problem. Stop being a part of the problem.