Modern GWAS can identify 1000s of significant hits but it can be hard to turn this into biological insight.
I'm excited to share our new work combining genetic associations and Perturb-seq to build interpretable causal graphs, out today in @Nature:
Hold on to your hats! The winners of the 2024 #NikonSmallWorldInMotion competition have finally been revealed, and they're sure to blow you away. View the full video gallery here: https://t.co/sQ5ahDQMC8
🚀New update to #AlphaFold Database: Foldseek now integrated!
Peer deeper into evolution with new structure-based search feature to find similar proteins with remote homology. The search includes experimentally-determined protein structures from @PDBe.
https://t.co/9L0RGX0CPx
Distruggere le piante di riso modificato geneticamente, frutto del lavoro e dell’ingegno dei ricercatori, è come bruciare i libri in piazza. Anche se non ha la stessa potenza simbolica, ha lo stesso significato. Solo che a farlo non sono dei neonazisti ma degli ecoterroristi.
🪱"All genes are created equal, but some are more equal than others" Happy to share our recent work dissecting a parent-of-origin effect in worms, which could have important implications for our understanding of the evolution of imprinting @IMBA_Vienna
https://t.co/CIbrG1MLbf
1/13 🚨🚨 I am so excited to present our new paper, six years in the making. Here, we provide the first strong evidence that there is a molecular mechanism behind the origins of living fossil lineages! #biology#science#paleontology https://t.co/8wW3DVXD1P
Proudly presenting our new findings on how #RNA binding proteins (RBPs) may increase the tolerance of genomes to transposable element (TE) insertions. If you want to know more read this thread or our story @Nature
https://t.co/VNW7SgGBua
1/13
I’m thrilled to announce our comparison of the C. elegans and C. briggsae embryonic lineages by scRNA-seq, led by a talented postdoc, Chris Large, with @RupaKhanal11, Bob Waterston, @JunhyongKim and LaDeana Hillier
Last January, I noticed something peculiar in my 2yo’s bedroom that - after a year of obsessive reporting - led me to a profound cosmic revelation about what’s even possible in our universe. A 🧵.
New publication: The histone chaperone SPT2 regulates chromatin structure and function in Metazoa https://t.co/Jj26aEuGKE @NatureSMB @GiuliaSaredi #DNADamage#DNARepair
NEW: we don’t reflect enough on how severe the housing crisis is, and how it has completely broken the promise society made to young adults.
The situation is especially severe in the UK, where the last time house prices were this unaffordable was in ... 1876.