Dr. James Canton

Leading Futurist, keynotes advise startups CEO Institute for Global Futures, Partner Green Capital Ex Apple Top10 AI/Tech/Env Future Smart book

[Cointelegraph @Cointelegraph]

⚡️ INTERESTING: 1X Technologies has begun mass production of its NEO humanoid robot in California, targeting 10,000 units annually and aiming to surpass 100,000 annually by 2027.

[Night Sky Today @NightSkyToday]

🚨: Physicists have succeeded in creating an observable "Time Crystal."

[Podcast Alpha @PodcastAlphaX]

Launch cost was $10,000/kg ten years ago. It's $1,000/kg today. At $300/kg, space data centers beat terrestrial on price.

Planet Labs CEO Will Marshall (on @theallinpod) laid out the math. Space-based solar panels face the sun 24 hours a day - no batteries, no backup generation. 5x more energy per panel than ground-based solar. That power advantage, combined with $300/kg launch costs, makes space compute cheaper than building a terrestrial data center.

Planet has already launched NVIDIA GPUs into orbit. A Google TPU test is in planning.

The one variable: Starship. Watch SpaceX's stated launch cost per kilogram each quarter. That number is the only thing separating Marshall's thesis from a funded business plan.

The launch cost model and what it means for Planet's valuation ceiling: https://t.co/WkJeVNmDSq

Source: All-In Podcast - https://t.co/PBP9iJLcZF

[TheNewPhysics @CharlesMullins2]

🚨 WHAT IF A SINGULARITY COULD EXIST WITHOUT A BLACK HOLE?

Physicists have discovered new mathematical evidence that so-called "naked singularities" can form in higher-dimensional spacetime.

A singularity is a point where gravity becomes effectively infinite and the known laws of physics break down.

Normally, physicists expect these regions to be hidden behind an event horizon inside a black hole.

But new research suggests that under certain conditions, singularities may exist without that protective veil.

Why this matters:

• It challenges one of the most important ideas in gravity theory: the cosmic censorship conjecture

• It suggests there may be situations where the universe exposes its deepest breakdowns directly

• It reveals strange self-similar "ripples" in spacetime that can evolve into naked singularities and microscopic black holes

• It may help physicists understand where Einstein's theory of general relativity reaches its limits

The unsettling implication is this:

If naked singularities can exist, there may be regions of the universe where the laws of physics become visible rather than hidden.

For now, the result exists only in higher-dimensional mathematical models.

But it pushes scientists closer to understanding what truly happens at the edge of spacetime itself.

Follow for more frontier physics and reality-bending discoveries.

[Dr. James Canton @futureguru]

Future Readiness Rock Stars Best Companies for the Future https://t.co/jFd1EPfnyp

[Charly Wargnier @DataChaz]

🚨 Anthropic just dropped a FREE 23-page enterprise AI playbook, and it’s a must-read for anyone looking to scale their operations!

It’s essentially a free operating manual for turning Claude into your company's core infrastructure.

The main takeaway?

A generic model gives you generic output. To really win, you have to teach Claude exactly how your unique business works!

The results are incredible when you train AI on your company’s DNA:
→ L’Oréal hit 44,000 monthly users with 99.9% accuracy.
→ Lyft cut support resolution times by a massive 87%.
→ Rakuten sped up product releases from quarterly to bi-weekly!

The architecture making this possible is brilliant:
→ MCP connects Claude to your tools.
→ Plugins store reusable company knowledge.
→ Claude Cowork provides an intuitive interface.

Good AI adoption isn't buying disconnected tools. It’s making AI your actual operating system!

I pasted the link to the playbook in the 🧵↓

[Vaibhav Sisinty @VaibhavSisinty]

This is massiveeeee. 🤯

SpaceX just signed a deal where Google pays them $920 MILLION every single month. Not for rockets. Not for Starlink. For renting the computing power that runs AI.

Google is basically paying SpaceX to use 110,000 of their high-end chips to train and run AI models. From October 2026 through June 2029. Total value: roughly $30 billion.

And this is their SECOND deal. Last month they signed a $1.25 billion per month deal with Anthropic for the same thing.

Combined, SpaceX is now making ~$26 billion a year just from renting the machines that power AI.

A rocket company just became one of the biggest AI infrastructure providers on the planet. Right before what could be the largest IPO in history.

The AI race isn't just about who builds the best model anymore. It's about who owns the machines.
And right now, that's SpaceX.

[John-Paul Smiley @JohnPaulSmiley]

Injectable nanorobots may help heal spinal injuries

https://t.co/em87gGYJ6H

[Podcast Alpha @PodcastAlphaX]

Why does it matter whether AGI is conscious?

@demishassabis says build AGI first as an intelligent tool, define consciousness rigorously using those tools, then decide as a society whether to build systems that seem conscious.

His view: those are two separate problems. Conflating them now is a mistake.

Other labs, he implies, are not drawing the same line.

If consciousness becomes the regulatory flashpoint in AI policy - which it might - the labs with a principled early position will be better placed to shape the rules.

What Hassabis said and what it means for the policy landscape:

https://t.co/Ilv6V64Sak

Source: Stanford Graduate School of Business - https://t.co/SQTHAMxKKg

[Rand Group @randgroup]

70% of S&P 500 gains since ChatGPT launched come from AI stocks.

[Khairallah AL-Awady @eng_khairallah1]

Jensen Huang, CEO of Nvidia:

"Every engineer is going to have and manage hundreds of agents."

You can't manage hundreds of agents if you've never configured a single Claude Project.

No CS program teaches harness engineering.
No tutorial teaches agent memory architecture.
No degree prepares you to build a system that remembers everything about your work.

One builder mapped the entire thing out. Free. Step by step. No experience required.

This is the roadmap ↓

Bookmark this for the weekend.

[Science girl @sciencegirl]

Scientists Develop DNA Nanorobot That Targets Cancer Cells

A team of researchers at Karolinska Institutet has created a tiny DNA-based nanorobot designed to attack cancer cells while minimizing harm to healthy tissue.

One of the major difficulties in cancer treatment is that many therapies cannot distinguish perfectly between cancerous and healthy cells, often leading to unwanted side effects. The newly developed nanorobot aims to address this challenge by remaining inactive as it travels through the body.

Built using a technique similar to DNA origami, the microscopic structure stays folded shut under normal conditions. It is engineered to respond to the more acidic environment often found around certain tumors. When it detects these conditions, the nanorobot unfolds and releases molecules that activate Tumor Necrosis Factor (TNF) receptors sometimes referred to as “death receptors.”

These receptors can trigger apoptosis, the body’s natural process of programmed cell death. Although scientists have long explored using these receptors in cancer therapy, a major obstacle has been avoiding damage to healthy cells that also carry them. The nanorobot’s pH-sensitive design provides a potential way to deliver the treatment more selectively.

In experiments involving mice with breast cancer, researchers reported a reduction in tumor growth of approximately 70%.

The technology remains in the early stages of development and has not yet been tested in humans. Future research will focus on evaluating safety, testing the approach in more advanced cancer models, and exploring whether the nanorobots can be adapted to target additional types of cancer.

Source: IBSA Foundation – “Nanorobot to target cancer cells and spare healthy ones.”

[a16z @a16z]

Mira Murati says human-AI collaboration needs models that can listen while they think:

"The types of models that we work with today, they're very turn-based. You talk, they talk, then they go off and think."

"While they're thinking, it's almost like they're deaf and blind. They cannot perceive anything else about what's going on."

"By contrast, our interactions with each other are very rich. There is a lot of information in our interactions when we are silent, when we're thinking, when we're interrupting one another."

"Interaction models are able to capture all of this nuance. They're not turn-based. They're more like time-based interaction, where they're continuously taking in audio, text, video, and continuously providing output."

"This enables you to catch things like interruptions and simultaneous speech, and really create a rich, high bandwidth interaction between humans and machines."

@miramurati at Bloomberg Tech live with @emilychangtv

[Massimo @Rainmaker1973]

One of the greatest difficulties in cancer therapy is that most treatments harm both cancerous and healthy cells, leading to severe side effects.

Researchers at Sweden’s Karolinska Institutet have now created a tiny DNA-based nanorobot to overcome this challenge. The device functions like a smart biological capsule: it remains securely closed while circulating through the body and only activates in the acidic microenvironment that surrounds many tumors.

Once triggered, the nanorobot releases molecular signals that activate Tumor Necrosis Factor (TNF) “death receptors” on cancer cells. These receptors initiate apoptosis, the cell’s own programmed self-destruction process.

Although scientists have long recognized the potential of death receptors for fighting cancer, healthy cells also express them, making selective targeting difficult. The new nanorobot addresses this using DNA origami technology. Its therapeutic payload is folded inside a precisely engineered DNA structure that stays locked in normal tissue but unfolds in the lower pH environment typical of tumors, delivering its instructions only where needed.

In experiments with mice bearing breast cancer, the treatment shrank tumor growth by approximately 70%.

The team plans to evaluate the system in more advanced cancer models, thoroughly assess potential side effects, and eventually explore human trials. Future versions could be programmed to target additional cancer types.

While still in early preclinical stages and tested only in animals, this approach represents a promising step toward more precise and less toxic cancer therapies.

[Wang, Y., et al. (2024). A DNA robotic switch with regulated autonomous display of cytotoxic ligand nanopatterns. Nature Nanotechnology. DOI: 10.1038/s41565-024-01676-4]

[Night Sky Today @NightSkyToday]

Incredible Auroras over Finland from last night...😍😍😍

[Josh Cook | Microsoft MVP @FlowAltDelete]

Microsoft is killing it with the IQ layer.

Work IQ.
Fabric IQ.
Foundry IQ.
Web IQ.

This is how agents get real context:
people, business data, enterprise knowledge, apps, files, Dataverse, and the web.

The companies that understand context will win the agent era.

Microsoft gets it.

What IQ does your agents use ?

[SciTech Era @SciTechera]

Anti aging progress

"Researchers found that semaglutide, the GLP-1 drug used in Ozempic and Wegovy, slowed multiple DNA-based markers of biological aging in a randomized, placebo-controlled human clinical trial."

"The study analyzed 17 advanced epigenetic clocks and found that semaglutide reduced the pace of biological aging by about 9% compared with placebo over 32 weeks."

"Researchers also observed improvements in aging biomarkers linked to mortality risk, inflammation, brain health, heart health, liver function, kidney function and metabolism."

It is some of the strongest evidence yet that a widely used medicine may influence the underlying biology of aging itself.

The future of longevity may come not from a single anti-aging pill, but from therapies that slow the cellular processes driving aging across the entire body.

[Canton Network @CantonNetwork]

Architecture that meets institutional requirements attracts institutions.

Privacy-preserving settlement, atomic composability, compliance-ready infrastructure, and governance participation built into the design.

[McKinsey Global Institute @McKinsey_MGI]

Could global prosperity expand 8.5x by 2100?

A Century of Plenty: A Story of Progress for Generations to Come tests whether that scale of growth is feasible within physical limits, resource constraints, and historical precedent, not as a prediction, but as a possibility.

https://t.co/GaRE2wadWe

[hypebeast.eth @hypebeasteth]

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