Felix Yarovinsy

[Felix Yarovinsy @fyarovinsky]

A fascinating and unexpected discovery—who would have predicted that macrophages possess magnetic properties and can contribute to navigation through magnetoreception?https://t.co/mQ2jJbLIJj

[Felix Yarovinsy @fyarovinsky]

Such a cool story!
https://t.co/l23rZp25AL

[Miriam Merad, MD, PhD @MiriamMerad]

Thrilled to see a new paper led by the outstanding @Brown_lab1, now out in Nature Biotechnology.
We provide mechanistic insights into how mRNA vaccines work. challenging key assumptions and offering new ways to control vaccine activity. (1/3)
Read here: https://t.co/zNZAGHJ9kd

[Felix Yarovinsy @fyarovinsky]

@danielleobarber A very interesting story! I’m looking forward to diving into it this weekend and discussing it at journal club.

[The American Association of Immunologists (AAI) @ImmunologyAAI]

This #DayofImmunology, we celebrate the "Guardians of Immune Balance"—Regulatory T Cells! 🛡️ Did you know a cornerstone of the 2025 Nobel Prize-winning research on Tregs was published in The Journal of Immunology?

In 1995, Shimon Sakaguchi and colleagues identified CD25 as a marker for these essential suppressor cells, forever changing our understanding of immune tolerance.

📖 Read the classic in @J_Immunol: https://t.co/TzuWCFuuxb.

[Amy Fan @amycfanphd]

Excited to announce our study (w/ @RukmanThota & @MaxKrummel) published today @Nature:
Macrophages “hold our living identities” by taking tiny bites from living cells and presenting this information to CD8 T cells.

https://t.co/9XENtFrB4h

#immunology #cellbiology @immunox @ucsf

[Felix Yarovinsy @fyarovinsky]

@theNASciences Congratulations to all newly elected members of the NAS! It’s inspiring to see such an outstanding group of scientists recognized in the Class of 2026.
A very special congratulations to Alan Sher, a pioneer in understanding cytokine biology and host–pathogen interactions.

[Felix Yarovinsy @fyarovinsky]

@Lo_Zanzi @harvardmed @Harvard Congratulations Professor Zanoni!

[Maxim Artyomov @maxim_artyomov]

In 2021 we identified GZMK+ CD8 T cells as Taa - age-associated subset of cells in mice. How they developed remained unclear.

Today, our latest work on the mechanism of development of age-associated GZMK+ CD8 Taa cells in old mice is now out!

https://t.co/4D2FsdxeOL

"Inflammaging in aged tissues drives remodeling of the CD8+ T cell compartment" let by Irina Shchukina and co-supervised by Gwendalyn Randolph with a huge team that helped to make it happen.

We definitively show that:

1. GZMK+ Taa cell development is cell extrinsic and requires antigen exposure in aged tissues.

2. We introduce major new model that accelerates immune aging in CD8 T cells and show that low-grade inflammation accelerates CD8+ T cell aging and Taa cell accumulation.

3. Aged adipose tissue acts as a niche that supports progenitor Taa cells and overall development of these cells.

[Felix Yarovinsy @fyarovinsky]

@sachinbhag That’s a great question—we haven’t yet examined the draining lymph nodes

[Felix Yarovinsy @fyarovinsky]

Very proud to share our work on macrophage disappearance reaction (MDR):

https://t.co/1zJLhHtyvc

A long-standing observation—now with a new mechanistic interpretation.

[Felix Yarovinsy @fyarovinsky]

Excited about this story as a continuation of our work on IFN-γ–mediated loss of tissue-resident macrophages—highlighting a broader principle of how inflammation reshapes macrophage niches. https://t.co/Zct0WSFy0s

[Felix Yarovinsy @fyarovinsky]

Loss of CD115 leads to disappearance of resident macrophages and opens the niche for recruitment of CCR2⁺ monocytes.

[Jonathan Kagan @jkagan1]

Too much data, too little thinking.
A important essay from Ruslan Medzhitov on the importance of understanding data, not just generating it. A must read.
@RMedzhitov @YaleIBIO
https://t.co/d3Q2Slp0hx

[The Colonna Lab @TheColonnaLab]

Excited to share that our work by @PatFernRod & @TongWu99 is published: RORγt⁺ DCs are a distinct lymphoid-derived lineage whose development is controlled by REV-ERBα/β, PRDM16 and PU.1, enabling pTreg induction and protection from Th2-skewed responses.

https://t.co/CKN3hhV9rz

[Cell Host & Microbe @cellhostmicrobe]

Bacteria’s babysitter role: Indole-driven immune truce in the womb
Preview of @CellCellPress work showing maternal microbiota, specifically tryptophan derivatives produced by commensals, promote maternal tolerance of the fetus to improve pregnancy outcomes
https://t.co/GsqjcEysm7

[Science Immunology @SciImmunology]

New research involving human organoids and mice shows that crosstalk between commensal E. coli that express flagellin and intestinal epithelial cells coordinate intestinal #macrophage recruitment to support #GutBarrier homeostasis. https://t.co/mWTglDjLER

[The American Association of Immunologists (AAI) @ImmunologyAAI]

⚠️ Research interrupted by 2025 funding cuts? AAI is here to help. Applications are now open for the second round of the AAI RESTORE Grants Program. We’re helping meritorious projects stay on track after unexpected grant terminations.

🔹 Who: Early-career researchers & PIs (R, K, F series, DP2/DP5, and more).
🗓️ Deadline: February 5, 2026.
💻 Apply: Log in to your AAI member account at https://t.co/ROptzBirqM