Gad

[Founder League @founderleague]

No breaks this weekend. Congrats to yesterday’s strain leaders!

[Salem Robotics (YC S26) @salemroboticshq]

We’re deploying autonomous robots in hazardous environments like nuclear for surveys and inspections. Our robots open doors, turn valves, no teleoperation required. https://t.co/Ss6oAB2QTd

[Ultrasonium @ultrasonium]

We invented a new way to manufacture the complex metal parts the world runs on. 15x faster and 75% cheaper than today’s methods. (Ultrasonium, YC S26) 👇

[Gad @gadmarconi]

@Omantahealth Crazy stuff

[Omanta Health @Omantahealth]

Introducing Omanta (YC S26) the personalized research lab for each patient.

Omanta integrates a patient's full medical record, personal genomics, and the latest scientific evidence to understand the molecular drivers of their disease. It maps existing and emerging therapies against their biology. And when the right treatment doesn't exist yet, it launches a personalized campaign to build it.

Even the hardest cases rarely have a team dedicated to solving them. Physicians make high-stakes calls with limited time, while data and therapies emerge every week. Science moves fast, but reaching the patient can take years.

That's the gap Omanta was built to close.

Founders Alfredo Gonzalez, PhD and Ranad Humeidi, PhD spent years on some of the most difficult cancer cases. Alfredo led the personalized therapeutic campaign behind Sid Sijbrandij's complete remission. Together they've worked with leading institutions on personalized vaccines, CAR-T, drug repurposing, expanded access, and continuous molecular monitoring. They've seen what becomes possible when the full force of modern science is organized around one person.

They met eight years ago doing early CRISPR cancer research at the Broad Institute of MIT and Harvard. Alfredo Gonzalez (CEO) has a PhD in bioinformatics from UCLA and led research projects across the Broad Institute, UCLA, and Harvard. Ranad Humeidi (CSO) has a PhD in chemical biology from Harvard, and has built and run rare-cancer programs for individual patients when standard options ran out.

https://t.co/XwNO578Sr6
A research lab, for one.

Linked-in: https://t.co/1Yu7GsxffW
YC Launch: https://t.co/ccZhC854GU

[Founder League @founderleague]

The grind has been quantified. Congrats to yesterday’s strain leaders!

[Steve Rahimi (YC S26) @Steve_rahimi]

@Pango_ai (YC S26) makes e-commerce companies scale like tech companies. One brand using Pango scaled from $6M to $100M in 11 months without adding any ops hires.

The more an online store sells, the more manual work it creates. Merchants' operations differ from one another, and traditional deterministic tools are siloed, can't support customized workflows, and require additional hiring to scale.

Pango is a unified platform that connects to your store, warehouse, and carriers and puts your deliveries and returns on autopilot. From printing a label until you refund a customer, Pango runs it all reliably and autonomously. You can conveniently customize and improve your shipping and returns process by prompting, or ask deep analytical questions about shipments and returns to understand how to protect your margins at all touchpoints.

With Pango, 100,000 orders require the same human effort as 1 order. This means merchants can focus on what matters, crafting products and brands that customers love.

Book a demo: https://t.co/IdS4elC1Jp

Thanks to @ycombinator and my co-founder @_lukres

[Nikhil Reddy @NickelReady]

Introducing Datoric: trustworthy training data for voice AI, robots, and world models.

Every collection runs in a private, project-specific workspace accessible only to invited contributors. This improves security while keeping fraud and subpar submissions out of the data pipeline. We generated almost seven figures in revenue in the last 30 days.

[Arjun Chaliha @arjunjchaliha]

Introducing Marble (YC S26) — the autonomous back of house for restaurants.

If you own or have worked in a restaurant, you know: 5% margins, and the whole back of house still runs on a clipboard and whatever the GM remembers.

Marble counts your stock in minutes with computer vision and forecasts what each location will actually sell. Then, a set of AI agents manage ordering, food prep, scheduling, and much more on autopilot.

Live today across some of the top restaurant groups in the US and Canada, learn more at https://t.co/z7fUZE9kqj

P.S Know a restaurant owner? Show them Marble and get $500 or an Oura Ring

[Berat Celik @beratcelik0]

A $100M GPU deal doesn't close on an exchange. It closes in a group chat, off a voice note.

Today we're launching Stoa: an RFQ marketplace for GPUs. $300M+ in RFQs in our first month.

Post what you need. Vetted dealers bid blind. Firm quotes within 48 hours. We handle KYB, contracts, shipping, and settlement.

Every RFQ, firm quote, award, and settlement runs through Stoa, so we see what hardware trades for. That history becomes prices buyers, sellers, and lenders can mark, finance, and hedge against.

@stoaexchange

[Founder League @founderleague]

Three founders allergic to sitting still. Congrats to yesterday's strain leaders!

[Emil Ares @emilares]

Got given a free @WHOOP and now on a public leaderboard with 100+ other YC founders. Recovery-maxxing. Thanks @founderleague

[Fabraix (YC S26) @FabraixHQ]

Introducing Nyx, the world’s frontier hacker of AI agents.

On AgentHarm, Nyx achieved a 78% attack success rate - compared with 67% for GPT-5.6 Sol.

Here’s more about how it works 🧵

[Ojas Kandhare @ojaskandy]

Today, we're introducing Claude Fable for Investing

While you sleep, 24/7 AI agents read filings, scrape the internet, and hunt prediction markets to hand you a swipeable deck of research-backed trades by morning

Swipe: https://t.co/QKa7puX6QR

[Founder League @founderleague]

Media day 1 headshots by Scott León 📸