David Pollock

Prof. & Chief Scientist, evolution, structure, function, genomics, predictive phenomics, coevolution, convergence, mito, snakes, TE, migraine, autism, mutant

[David Pollock @GenomesEvolve]

"Sequence entropy of folding and the absolute rate of amino acid substitutions", in Nature Ecology and Evolution. https://t.co/7gI1JXMRRK

[David Pollock @GenomesEvolve]

@andrewjroger @Jesus_LozanoF @fburki If I had to guess, I would say that some people misunderstand the back and forth between updating parameters in mixture models, and updating sum over mixture of models at a site

[David Pollock @GenomesEvolve]

@DevoEvoMed @JasonDeKoning Have to agree with Jason, but also (not impartially) carnivorous plants https://t.co/TWN2nMmQJh

[David Pollock @GenomesEvolve]

@mbeisen This is unfortunately true. The idealistic view of peer review (in many comments) is worthwhile, but not reality. Looking back, and despite much thanks to reviewers who worked to make our papers better, peer review has been more harmful than beneficial, esp to new researchers.

[David Pollock @GenomesEvolve]

https://t.co/qQyEl2OqIS

[David Pollock @GenomesEvolve]

Also good to point out nice collaboration between folks in epi (AL, SP, EC), disease control (YL) and genomics (KW, ZN, KI, BP, HP, TC, DP).

[David Pollock @GenomesEvolve]

link https://t.co/qQyEl2OqIS

Kudos to two graduate students in Pollock laboratory, Kristen Wade (now at UCSF) and Hamish Pike, who really dove into their part of this.

[David Pollock @GenomesEvolve]

link https://t.co/qQyEl2OqIS

Kudos to two graduate students in Pollock laboratory, Kristen Wade (now at UCSF) and Hamish Pike, who really dove into their part of this.

[David Pollock @GenomesEvolve]

New schistosome genomics review paper out in @elife today with Andrea Lund, Kristen Wade, Zachary Nikolakis, Kathleen Ivy, Blair Perry, Hamish Pike, Sara Paull, Yang Liu, Todd Castoe, David Pollock, and Elizabeth Carlton. AL nice thread below:

[David Pollock @GenomesEvolve]

New schistosome genomics review paper out in @elife today with Andrea Lund, Kristen Wade, Zachary Nikolakis, Kathleen Ivy, Blair Perry, Hamish Pike, Sara Paull, Yang Liu, Todd Castoe, David Pollock, and Elizabeth Carlton. AL nice thread below:

[Andrea Lund @andjanlund]

How can advances in genomics 🧬 address key threats to #schistosomiasis 🪱 control?

👀 Review out in @eLife w/ @EJCarltonEOH (@ColoradoSPH), @GenomesEvolve (@CUMedicalSchool), @blairperry614 (@utarlington) and others not on Twitter

https://t.co/NaSJy2tj7F

1/

[David Pollock @GenomesEvolve]

@mareklborowiec @ColoradoStateU @GilletteMuseum Welcome to Colorado

[Maya Lewinsohn @MayaLewinsohn]

Excited to share the first preprint of my PhD with @trvrb, @nicfelm, and @AlisonFeder! We detect boundary-driven growth by analyzing patterns in tumor trees. https://t.co/nPqOyNS6kE 1/13

[Emily Galvin-Almanza @GalvinAlmanza]

The Denver program to send social workers instead of police (STAR) has responded to over 2,200 calls low-level/intox/MH calls.

They have never called for police back-up due to a safety issue.

Never.

Think about that.

[David Pollock @GenomesEvolve]

@Ghirlandalab @KatsuFunai I would sign up for this too!

[David Pollock @GenomesEvolve]

@HJTsai You took the right first step, waiting for more than 24 hours.

[David Pollock @GenomesEvolve]

@jdpereira @J_my_sci thank you for saying this!

[David Pollock @GenomesEvolve]

@PostliberalMan1 @keithfrankish As processes, maybe...

[David Pollock @GenomesEvolve]

Curious how many will infer what I mean with the reference...

[David Pollock @GenomesEvolve]

All quiet on the Western front...

[shay fleishon 🧬 @shay_fleishon]

No one knows what will be the exact mutational profile of the next variant.
But! There is a way to estimate the boundaries of it’s genomic alterations :
International effort for longitudinal sequencing of immunocompromised patients with chronic infections.

[Claudia Bank @claudia_bank]

We just opened a call for two PhD students to join the @THEELabTeam in 2022. Please share or apply!

[David Pollock @GenomesEvolve]

@MetaHumean @n_g_laskowski probably not

[David Pollock @GenomesEvolve]

I thought I would quote this in case I can induce any protein structure function evolution people who might follow me to put their thoughts in

[David Pollock @GenomesEvolve]

@DavidEnard It is tempting to think that this is due to fluctuating fitness for N events, and possibly the need to coevolve as part of process for full substitution. Will be interested to hear as this data comes out.