Graham MacLeod, PhD

Functional genomics, drug discovery, cancer research and regenerative medicine. @angerslab, Donnelly Centre at the University of Toronto

[Donnelly Centre @DonnellyCentre]

The Donnelly Centre is hiring a Research and Communications Officer! This role covers the external and internal communications of our community: from news stories and social media, to web page management and event support.

https://t.co/wNqLa4KuHZ

[Science Signaling @scisignal]

Don’t miss the new issue of #ScienceSignaling!

New insights into Wnt signaling could inform the design of rational ligands for therapy, a Review discusses the latest discoveries about the origins of brain metastases and potential targets, and more. https://t.co/mkSml1tENg

[Donnelly Centre @DonnellyCentre]

Congratulations to Stephane Angers and all the hard-working teams funded by Genome Canada's Genomic Application Partnership Program!

Angers will be the academic leader alongside Tracy Stone, Director of ProteinQure, in this GAPP-funded project: https://t.co/VjRHrxWI96

[Donnelly Centre @DonnellyCentre]

The Donnelly Centre is looking for a new team member!

We're hiring a Financial Assistant to help process a variety of activities and prepare information for budget planning and reporting.

See below for more information: https://t.co/YtvNdFmKXU

[vijay ramaswamy @vijayvijay1979]

https://t.co/9M132CIhWe

[Ben Perrin @profbenperrin]

Science editorial: Poilievre "echoes rhetoric used by U.S. President Donald Trump’s administration to justify canceling research grants and shutting down government programs—has alarmed many researchers."

https://t.co/tlGxbY4Nc4

[Stephane Angers @StephAngers]

Register for the upcoming Wnt Signaling GRC taking place June 22 – June 27, 2025, at Bates College in Lewiston, Maine, USA.
The conference program, developed by conference chairs, Madelon Maurice and Ken Cadigan, highlights the cutting-edge work being conducted in the field. 1/2

[Rony Chidiac @chidiacrony]

🎉 Excited to share our latest work in @stemcellreports! This marks the final chapter of my postdoc in the @angerslab. https://t.co/XVM4X17CLZ
🧬✨ We show how individual Frizzled receptors regulate Wnt-β-catenin signaling kinetics in hPSCs, influencing mesoderm commitment🧵1/n

[Graham MacLeod, PhD @ggmacleo]

@BrainSurgn1989 @lincolndstein @MarioniLab @BenSimons_Lab @SpringerNature @Nature Congrats Peter and team!! Amazing work!

[Gary Bader @garybader1]

New postdoc opportunity in multiscale mapping of human model tissue systems https://t.co/q7hPxk6mSD @acceleration_c @DonnellyCentre

[Graham MacLeod, PhD @ggmacleo]

@LindseyLabGroup @UM_RadyFHS @um_HACS_GSA @umanitoba @manitobaneuro @CAN_ACN @StemCellNetwork Congratulations on your new facility!

[Lindsey Lab @LindseyLabGroup]

Thanks Global News for celebrating the Grand Opening of the new Rady Biomedical Fish Facility with us this week! @UM_RadyFHS @um_HACS_GSA @umanitoba @manitobaneuro @CAN_ACN @StemCellNetwork

https://t.co/L6fa8FNZ5T

[John Morris @johnomix]

For no reason in particular, I would like to remind everyone that we have a Functional Genomics faculty position opening at the @DonnellyCentre at the University of Toronto (in Canada 🇨🇦) 👀 #ASHG24 https://t.co/bHtZBpFeMT

[Graham MacLeod, PhD @ggmacleo]

This is a continuation to our ongoing collaboration with @BrainSurgn1989 and also includes contributions from @DanielSchramek 's lab.

[Graham MacLeod, PhD @ggmacleo]

New research from our GBM team in the @angerslab, co-led with @MolaeiFatemeh We leveraged our genome-wide CRISPR screen results and designed a focused library to dig deep into subtype-specific vulnerabilities in Glioblastoma stem cells. https://t.co/K66oXcBge7

[Graham MacLeod, PhD @ggmacleo]

We show consistent functional differences between the "Developmental" and "Injury Response" patient-derived GSC cell lines that point to therapeutic vulnerabilities in each state.

[Donnelly Centre @DonnellyCentre]

A team led by @UofT researchers has uncovered new targets that could be key to effectively treating #glioblastoma, a lethal type of brain #cancer.

Glioblastoma is challenging to treat due to the resistance of its stem cells to therapy.

Learn more 👉 https://t.co/Ld55RJCChH

[Lucie Wolf @_LuWo]

Very cool to be featured in 'Humans of RHSE'! @RHSE_UofT @DonnellyCentre @StephAngers Read more about my postdoctoral work and beyond here: https://t.co/erLSwkeebt

[John Morris @johnomix]

It's faculty job application season so why not apply to the University of Toronto and be my colleague at the
@DonnellyCentre! We have a tenure-track opening to do functional genomics research at our world-class institute. Check it out and apply by Jan. 16! https://t.co/bHtZBpFeMT