Giuseppe Dario Testa

Geriatrician & PhDc @UNI_FIRENZE◾Former Fellow @mcgillu - PeriOp Program (POP)◾Former Chair @EuGMSSociety SIG on Meta-analysis ◾#Periopmed #Prehab & #GeriOnc◾

[NIHR Southampton BRC @SouthamptonBRC]

🚴 Can prehabilitation improve recovery after heart valve surgery?

Our BRC is delivering CardioFit – a pioneering trial testing supervised exercise before cardiac surgery to improve patient outcomes. Turning evidence into NHS impact 💙

👉 https://t.co/V12eKPUrDO

[Yüksel Ürün @DrYukselUrun]

Lung cancer screening works.
🔘Low Dose CT caught 97% of cancers—most in early stages.
🔘77% had surgery. 1-year false-positive rate? Just 4.8%.
This isn’t just data—it’s time saved. Lives extended.
#LungCancer #Oncology #EarlyDetection #PublicHealth @TheLancetOncol @OncoAlert @IASLC
https://t.co/5AEPjrZ2O2

[Ben Kirk, PhD @DrBenKirk]

How good is serum Creatinine/Cystatin C at identifying low MRI- Muscle Volume and low grip strength in 9,731 - 149,707 Older Adults?

Open access in @geronsociety . Happy reading:

https://t.co/hXhIg2yDyZ

#Muscle #Biomarkers #Sarcopenia

[Riccardo Campi @Ric_Campi]

We look forward to welcoming you all in beautiful Florence!

@AOUCareggi @dmsc_unifi @UNI_FIRENZE @EAUYAU_RenalCa

[Carla Prado, PhD, RD, FCAHS @DrCarlaPrado]

Consequences of muscle as a locomotor vs metabolic organ (sarcopenia vs. low muscle mass)
https://t.co/nb2YjDY6aK
Expanding the discussion on https://t.co/KL1GoY1sxr
and
https://t.co/B6PfT4P5Z2

@Kryz5559 @mackinprof

[Florence Multidisciplinary Expert Meeting on RCC @Flo_exp_RCC_25]

📆 On 17-18 January 2025 we will host the first edition of the Florence Multidisciplinary Expert Meeting on Renal Cell Carcinoma.

Scientific Program 👉https://t.co/0QVD859WPs

🎬The meeting has been designed by the @AOUCareggi Urologic Multidisciplinary Tumor Board to allow a group of international, renowned #experts from multiple disciplines to meet in a friendly atmosphere and discuss the latest #advances and #controversies in the diagnosis and management of #renalcellcarcinoma.

🎯State-of-the-art lectures, semi-live surgeries, and case-based debates will provide a unique framework to share knowledge and experience, leveraging the power of #multidisciplinary approach to advance the field from clinical, educational, and scientific perspectives.

🔎 The meeting will also represent an opportunity to develop new #research networks as platforms for future collaborative projects and clinical trials.

You can follow the meeting for free (online only 🖥️): click here to register
👉Day 1 (January 17th, 2025): https://t.co/WjHzDBEzqC
👉Day 2 (January 18th, 2025): https://t.co/VU59amsAAp

For any questions please contact our team:
📩 [email protected]
📩 [email protected]

We truly look forward to sharing this event with you all!

Merry Christmas and Happy New Year! 🎄

The Presidents and Scientific Committee

[JAMA Neurology @JAMANeuro]

Study found frailty accelerates up to 9 years before dementia onset and is a key early marker. Frailty was linked to higher dementia risk even when measured years before dementia onset and may represent a target for prevention efforts.

https://t.co/cN6TI5jqvW

[Tash Masud @TashMasud]

A nice article . Yes controlling. Hypertension is important in all ages but in frail older people we should show some caution in not overdoing it

[Giulia Rivasi @RivasiGiulia]

A geriatric point of view on the 2024 ESC Hypertension Guidelines ⁦@rprestamd⁩ ⁦@EnricoBr1MD⁩ #ESC https://t.co/CEAlHzKlcR

[Dr. Myohead @DrMyohead]

Repeated passive heat treatment increases muscle tissue capillarization, but does not affect postprandial muscle protein synthesis rates in healthy older adults

Nice work from @Cas_Fuchs @MilanWBetz @Hendriks_FK et al

https://t.co/cRZOsO5qe7

[Paul Wischmeyer MD @Paul_Wischmeyer]

🙋‍♂️NEW Online! Muscle: A Critical Organ For Survival & Recovery in Critical Illness

🙏 Honored to work with @mackinprof & @drcarlaprado

🔗https://t.co/oLRDpPEj2R

📧Feel free to email me for full PDF at [email protected]
#icurehab #foamcc #muscle

[Giuseppe Dario Testa @giuse_testa]

https://t.co/755Dl79xta

[Jugdeep Dhesi @JKDhesi]

Yup, we are seeing between 1 in 4 & 1 in 7 older patients choosing a non operative route when BRAN approach used in #CGA based #POPS perioperative services across the UK @GeriSoc @CPOC_News (article about this approach/ impact on SDM/outcomes just accepted -will share soon!)

[Giuseppe Dario Testa @giuse_testa]

Thanks again to all of you for the amazing experience! @EuGMSSociety

[Jackson Fyfe, PhD @jacksonfyfe]

Resistance training can be complicated.

But the truth is, many approaches “work”:

“All combinations of load, sets, and weekly frequency improved strength, muscle mass, and physical function compared to the non-exercising control group”.

The best program is the one you can stick to.

https://t.co/NzE3RaWfvA

[CA: A Cancer Journal for Clinicians @CACancerJournal]

💡Why is geriatric assessment (GA) important in cancer care? GA offers a comprehensive evaluation of an older adult's health, helping to tailor interventions that improve treatment completion, QOL, and advance care planning.

https://t.co/Bl6QXM5Qoy

@OncoAlert #GeriOnc #ESMO24

[Scott Lear, PhD @DrScottLear]

After 30 yrs, muscle mass ⬇️due in part to lack of activity & insufficient protein.

"older people’s muscles can’t use dietary protein as effectively as younger people"

@james_mckendry explains why protein matters & what type is beneficial.
@mackinprof
https://t.co/nvrhyhO7Yn

[Carla Prado, PhD, RD, FCAHS @DrCarlaPrado]

Hot off the press:
Muscle Matters: the Impact of Medically Induced Weight Loss on Skeletal Muscle.

https://t.co/7NPXV1JKBD
@TheLancetEndo

Pérdida de masa muscular con medicamentos para la pérdida de peso.

Perda da massa muscular com medicamentos para perda de peso.

“Regulatory agencies should provide more comprehensive guidelines for monitoring and evaluating body composition changes, mandate well-designed body composition studies, and enhance post-market surveillance."

"GLP-1 receptor agonists have revolutionized obesity treatment and demonstrated substantial benefits... However, the potential impact of muscle mass loss as now observed remains a concern. These highly effective medications should be used strategically, in a multimodal approach to improve the quality of weight loss by optimizing body composition."

Thanks to my dear colleagues/friends: @mackinprof @Kryz5559 and Steven Heymsfield for their partnership!

@UofAALES @AlbertaDiabetes @UofAResearch
Figure: Dual role of muscle as both a structural and metabolic organ.

[Jackson Fyfe, PhD @jacksonfyfe]

How much exercise is needed to increase life expectancy?

Turns out a little goes a long way.

This new study in over 71,000 people (aged 60+) found:

➡️Higher volumes and intensities of exercise = greater benefits (up to 3.5 to 4.6 extra years for women and men, respectively).

➡️BUT - just a 10 min brisk walk daily was enough to add 0.9-1.4 years to modeled life expectancy.

https://t.co/BtgLU9ruoI

[Stuart Phillips (he/him) @mackinprof]

Nothing recent about high protein 'causing' kidney problems. It's >50yr old hypothesis...

We and others have shown this thesis is incorrect using RCT data and not observational data, which is what this study is.

Still, on message with the fact the original thesis was incorrect. That's not intellectual dishonesty but simply how science works. Maybe you'll be wrong someday? Having the courage to admit it, or not, is where the dishonesty comes in!