Mathilde Garcia

I am an associate professor at @Sorbone_univ_ and work at @LCQB_UMR7238 on N-terminal ends of protein nascent chains, and their impact on protein life cycle.

[Mathilde Garcia @gmathildegarcia]

Très émue et honorée que Salomé Nashed, ma première étudiante en thèse @LCQB_UMR7238 @Sorbonne_Univ_
ai été distinguée par le prix Prix Jeunes Talents France l'Oréal-Unesco! Un grand bravo à elle #4womeninscience

[Mathilde Garcia @gmathildegarcia]

@slecrom @Sorbonne_Univ_ @LCQB_UMR7238 @4womeninscience Bravo Salomé! Très émue et honorée de cette distinction attribuée à ma première étudiante en thèse.

[Stéphane Le Crom @slecrom]

Félicitations à Salomé Nashed, doctorante de @Sorbonne_Univ_, qui travaille au @LCQB_UMR7238 en bioinformatique sur l'adressage des protéines à la mitochondrie, pour l'obtention du prix Jeunes Talents France @4womeninscience #FWIS

[Mathilde Garcia @gmathildegarcia]

We identify and experimentally validate a conserved signature at position 2 of the MTS that is typical of N-terminal acetyltransferases C potential substrates.

[Mathilde Garcia @gmathildegarcia]

Main results of pour preprint @biorxiv_genomic
https://t.co/rJqBFvSdvO

[Mathilde Garcia @gmathildegarcia]

We find that the amino acid in position 2 segregates proteins located in different cellular compartments. The signal is strong and highly specific to that position.

[Mathilde Garcia @gmathildegarcia]

We identify and experimentally validate a conserved signature at position 2 of the MTS that is typical of N-terminal acetyltransferases C potential substrates.

[Mathilde Garcia @gmathildegarcia]

We find that the amino acid in position 2 segregates proteins located in different cellular compartments. The signal is strong and highly specific to that position.

[Elodie Laine @LaineElodie]

Discovery and validation of functionally relevant N-terminal signatures across the yeast proteome! Great collaboration with Mathilde Garcia. @LCQB_UMR7238 1/3

[Mathilde Garcia @gmathildegarcia]

How we discovered and experimentally validated the role of N-terminal residues for NatC recruitment and efficient import of mitochondrial precursors.
See our preprint on functional exploration of N-terminal signatures in the yeast proteome.
https://t.co/rJqBFvSdvO