Rike Gorki

PhD Student w/ Eicke Latz and Jan van den Bossche (Bonn / Amsterdam). 💜 innate immune signaling and metabolism 🧫👩🏼‍🔬

[Charité - Universitätsmedizin Berlin @ChariteBerlin]

Die #CharitéBerlin begrüßt Prof. Eicke Latz – ihren neuen Professor für Experimentelle Rheumatologie & Wissenschaftlicher Direktor des @DRFZ_Berlin! Ziel des Immunologen: Therapien & Prävention bei chronisch-entzündlichen Erkrankungen voranbringen. 📷 DRFZ https://t.co/hBE7zhOSm5

[Rike Gorki @GorkiRike]

Read this #preprint on @researchsquare: Sphingomyelin d18:1/14:0 activates TLR4 in metaflammation https://t.co/Evbr4hyBjy

Happy to share our preprint! Grateful for this joint effort, linking endogenous TLR4 activation with metaflammation 🔥

[Rike Gorki @GorkiRike]

@FabiAlexFischer @bsicongress Congrats Fabi! 🎉😊

[Wilhelm Lab @LabWilhelm]

Our latest study highlighting a link between infection-induced ketogenesis and T cell function @Nature Huge team effort @Fokaragiannis @PeukertKonrad @surace_laura @christianbode10 @PlacekKasia and many more https://t.co/x5BvNN3dTl

[Rike Gorki @GorkiRike]

Translational application of 2-DG! targeting metabolism to fight viral infection 🙌🏻

[Thea Gorki @GorkiThea]

Thanks to an amazing team and great collaborators our first paper at G.STAntivirals is on BioRxiv 🥳🥳
'Host-directed therapy with 2-Deoxy-D-glucose inhibits human rhinoviruses, endemic coronaviruses, and SARS-CoV-2'
https://t.co/f02h6m9GjS
We're happy about every RT and comment

[Rike Gorki @GorkiRike]

Happy to have been part of yet another nice story! Zooming into the immunometabolite 2HG in my most favorite cells (macrophages of course) 👩🏼‍🔬🧫

[Jan Van den Bossche Lab @immunometlab]

❗️New kind in town of immunomodulatory signaling metabolites in macrophages❗️

We describe D-2HG among the top-induced immunometabolites in inflammatory macrophages that serves as a negative feedback loop to resolve inflammation

➡️https://t.co/3ZaiwbheGZ

[Rike Gorki @GorkiRike]

It’s out! Our guide for everyone new to studying macrophage metabolism 🧫

@immunometlab @XanthevD @RafaJArguello & our two first authors 👏🏻

An integrated toolbox to profile macrophage immunometabolism https://t.co/1YzcFCLy4D

[Prof. Hao Wu @WuLabHarvard]

Alert! EMBO conference on inflammasomes during Oktoberfest in Munich! It is a hybrid if you cannot make the trip. Register and beer up! @v_hornung @inflammasomelab @dixitvishva @russellevance @jkagan1 @FitzgeraldKate @laoneill111 @broz_lab @Rebecca_Coll
https://t.co/sOcClTh168

[Rike Gorki @GorkiRike]

Pre-print that includes my Master Thesis Work is out...check it out if you are a fan of inflammasomes🔥 #pyrin #inflammasome #nlrp3

[bioRxiv @biorxivpreprint]

Clostridium difficile Toxin B activates the NLRP3 inflammasome in human macrophages, demonstrating a novel regulatory mechanism for the Pyrin inflammasome https://t.co/UDz3yEPTAH #bioRxiv

[Rike Gorki @GorkiRike]

Happy to contribute to this work investigating the metabolism of human DCs 🧫

[Jan Van den Bossche Lab @immunometlab]

α2-3 Sialic acid-binding and uptake by human monocyte-derived dendritic cells alters metabolism and cytokine release and initiates tolerizing T cell programming https://t.co/1woaEIELaK
Happy that we could help with the immunometabolic phenotyping of DCs @YvK13 @ScienceLab_MCBI

[Rike Gorki @GorkiRike]

Check out our Sneak Peak 🤓

[Jan Van den Bossche Lab @immunometlab]

Not sure which technique(s) to select to profile your favorite cell’s immunometabolism?
We set up an immunometabolic profiling toolbox and applied it to human and mouse LPS vs IL-4-stimulated “M1/M2” macrophages.
We = @RafaJArguello, @XanthevD, @GorkiRike & others not on Twitter

[Rike Gorki @GorkiRike]

An important and necessary step in the right direction 💊🦠

[BMFTR @bmftr_bund]

https://t.co/m0kFoLm006

[Wilhelm Lab @LabWilhelm]

Our view on how fasting shapes the immune response. 🍽💉 Enemy or ally? Fasting as an essential regulator of immune responses: Trends in Immunology https://t.co/laoUfbmeRT

[Nature Conferences @NatureConf]

Recent research in the field of metabolism and metabolic diseases has yielded insights into its role in cardiovascular disease, obesity, cancer and more. Join us at this virtual conference! @NatMetabolism @NatureCellBio @NatRevMCB

https://t.co/ZksDDhZONr

[Powell Lab @J_Powell_Lab]

Our recent paper evaluating #immunometabolism in #COVID19 is officially out @CellReports. Thanks to everyone at @JohnsHopkins and @HopkinsMedicine who helped make this paper a reality! https://t.co/2KeWSTUrl6
1/5

[Rike Gorki @GorkiRike]

Exciting news!

[Nature Cardiovascular Research @NatureCVR]

Launching in 2022 comes Nature Cardiovascular Research! This journal is dedicated to publishing original and important advances in cardiac, vascular and blood biology, covering fundamental, translational, clinical and public health research. Learn more at https://t.co/1ZBD3WAtrL

[Maxim Artyomov @maxim_artyomov]

THE ITACONATE PHENOTYPE!!
breakthrough from @MoniBambouskova et al

*LPS tolerizes WT macrophages to NLRP3 inflammasome BUT not Irg1-/- macs, they fully activate!
*Endogenous ITA acts downstream of ASC affecting caspase-1/GSDMD
*GSDMD-Cys77 is itaconated

https://t.co/MO6TIaut6T

[Rike Gorki @GorkiRike]

Very interesting paper worth the read!
https://t.co/03SVVwKE16

[bioRxiv @biorxivpreprint]

Murine ex vivo cultured alveolar macrophages provide a novel tool to study tissue-resident macrophage behavior and function https://t.co/IEN1av8yZY #bioRxiv

[Rike Gorki @GorkiRike]

Check out the latest work of @GorkiThea (i.e. my talented sister). For everyone interested in alveolar macrophages and tools for long-term culturing of primary macrophages ex vivo 🧫

[Thea Gorki @GorkiThea]

Check out our preprint about a novel tool to culture primary alveolar macrophages ex vivo over several month.
Best way to celebrate #WomenInScienceDay2021 as it is an all female team effort 😍
Happy about every share, RT and comment!

https://t.co/SeRywZ3vln