Grace Birch (PhD)

Postdoc in the Romee lab at DFCI, Boston working on CAR-NK cells and CIML NK cell therapy. Keen runner, coffee drinker and food eater!

[Wenxin (Vincent) Xu @VincentWenxinXu]

1/8 Our study on natural killer (NK) cell dysfunction in kidney cancer is now out @ESMO_open! Led by co-first authors @graceandscience and @aliameliki, and mentored by @romeerizwan, @drchoueiri, @BraunMDPhD. Link here 👇 https://t.co/Sv0ryRWPrf

[Grace Birch (PhD) @graceandscience]

Last day working in the lab for a while, it’s been fun navigating the lab space with this bump! 👩‍🔬🤰#38weeks

[Waggoner Lab @LabWaggoner]

Bulk and single-cell transcriptomics identify gene signatures of stem cell-derived NK cell donors with superior cytolytic activity @MolTherapy
https://t.co/vwIWFR04nP

[Grace Birch (PhD) @graceandscience]

Really cool work!

[Mohammad Rashidian @m_rashidian1]

1. Excited to share our paper in @ScienceAdvances. We developed an antigen-based CAR-PET imaging approach that enables in vivo detection of CAR T-cells with high sensitivity and specificity, without requiring genetic alterations. Here’s a brief thread:https://t.co/EDDjhUQpVy

[Rizwan Romee @romeerizwan]

It was awesome to host ⁦@rftbsr9⁩ and ⁦@sunilacharya13⁩ from ⁦@lab_rezvani⁩ ⁦@MDAndersonNews⁩ for a talk ⁦@DanaFarber⁩ today. Hats off to Dr Rezvani’s group for innovating the NK cell therapies. #NK #NKCar #Immunotherapy #Romeelab

[Trends in Microbiology @TrendsMicrobiol]

Phages to the rescue: in situ editing of the gut microbiota https://t.co/PbAMQTpd48

[Waggoner Lab @LabWaggoner]

An integrated single-cell reference atlas of the human endometrium @NatureGenet @magda_mareckova @LuzGarAl @KrinaZondervan
https://t.co/SSmQtEhZ5t

[Chen Weng @chenweng1991]

A recent commentary in bioRxiv discussed data analysis for our mtDNA-based lineage tracing technology ReDeeM. We welcome the points raised and are happy to address these concerns. We believe this will foster constructive dialogue (1/n) https://t.co/6aWbTRfijx

[Vijay Sankaran @bloodgenes]

There has been confusion over mitochondrial mutation detection, consensus variant calling, and lineage tracing in single cells. Here, we detail how ReDeeM addresses these challenges, improving detection of mtDNA mutations by 10-fold and lineage tracing. Led by @chenweng1991 and @JswLab, we now constructively address concerns raised: https://t.co/jtZIhXuHZn

Stay tuned for 🧵 from Chen.
#genomics #mitochondria #singlecell

[Mohammad Rashidian @m_rashidian1]

Excited to share our paper in @NatureBiotech. We've developed a CAR-Enhancer (CAR-E) that enhances the activity and persistence of CAR T-cells. These memory CAR T-cells can re-expand months later. Here's a brief summary: https://t.co/KpOwsAQ8qR

[Waggoner Lab @LabWaggoner]

Deletion of SYK resulted in more robust cytotoxic activity and cytokine production of CAR-NK due to negative regulation of ITAM-mediated signaling
#Millan #Lanier
https://t.co/04URDxgbCG

[Grace Birch (PhD) @graceandscience]

Super excited to share this work led by Mubin showing activity of CAR memory like NK cells against ovarian cancer

[Rizwan Romee @romeerizwan]

Excited to share this paper from my lab led by outstanding scientist Dr Mubin Tarannum #romeelab ⁦⁩ CAR memory–like NK cells targeting the membrane proximal domain of mesothelin demonstrate promising activity in ovarian cancer | Science Advances https://t.co/B5V7V44wBs

[Tanentzapf Lab @TanentzapfLab]

Science is a career full of rejection & self doubt. Most scientists don't go around collecting awards & kudos but sit there wondering if anyone reads our papers. Telling a scientist whose work you like that you value & appreciate what they do is a small & very meaningful gesture.

[Rizwan Romee @romeerizwan]

Promising mem-like NK cell study led by @Roma_Shap in MRD+ and or TP53mut AML undergoing RIC HCT..addressing a major unmet need. https://t.co/iO4nEnQWGJ

[Rizwan Romee @romeerizwan]

Excited to lead these efforts... Lot more to come. #Romeelab #NK #immunotherapy

[Rizwan Romee @romeerizwan]

Had a wonderful time at our summer lab picnic today #romeelab ⁦@MichalSheffer⁩ ⁦@RemyDulery⁩ ⁦@graceandscience⁩ ⁦@DanaFarber⁩

[Grace Birch (PhD) @graceandscience]

@romeerizwan @andreia77012 We always have fun at work! We had just finished a long stint in the hood.

[Grace Birch (PhD) @graceandscience]

Late shift gang, including visitors who used to be in the lab! #romeelab @romeerizwan @andreia77012

[Grace Birch (PhD) @graceandscience]

These are so cool! I need!

[Waggoner Lab @LabWaggoner]

Resetting the public’s understanding of how science works will be a big job, but a good place to start is with students who get science degrees by teaching the philosophy of science @ScienceMagazine
https://t.co/jMql4X9ZLK