Top Tweets for #ASGCT25
#TeamTenaya recently attended #ASGCT25, where the global cell and gene therapy community came together to share progress and possibilities. At Tenaya, we’re focused on advancing genetic medicines for the heart and moving bold science toward real-world impact. #HeartHealth
The @UCLIoN GTAC AAV team had a wonderful time at #ASGCT25! Thank you everyone for the inspiring work and enlightening discussions!
@DrJo_Ng @RebecaGilG @HesterChu Camila Vallve @kzhelcheska 🧬
@ASGCTherapy
That’s a wrap on #ASGCT25! We had a great time sharing our latest scientific progress and initiatives—from the launch of three new capsids for CNS, eye, and neuromuscular targeting, to the announcement of the Dyno Frontiers Program and our upcoming GATC conference this fall.
Learn more at https://t.co/Qw1SEcTjpp, and stay tuned for more exciting updates in the year ahead!
With the exception of KJ’s n-of-1 ABE (which alone was wonderful, beautiful, & inspiring enough to make it a memorable year), #ASGCT25 was rather bland, perhaps fittingly so given C&GTx’s challenges
Despite that, wanted to highlight random tidbits that caught my eye $XBI (1/10)
Here’s a recap of the data we presented at #ASGCT25 this afternoon on our newest neuromuscular capsid: Dyno-3hv!
As shared by Dr Megan Cramer in her talk, Dyno-3hv is the first capsid of its kind optimized for highly efficient delivery to the multiple tissues affected by neuromuscular disorders, including heart, skeletal muscle and CNS.
You can learn more about this capsid at https://t.co/QHsd1ElwX6 and about partnering with Dyno at https://t.co/guwEjYA5v7.
Tune into this episode of @BiotechTVHQ at #ASGCT25, where @BradLoncar and Eric Kelsic talk more in depth about the science behind the CNS, eye, and neuromuscular capsids we launched this week, as well as the Dyno Frontiers Program and upcoming GATC conference, and how they’re designed to help end users access better therapies by tackling delivery challenges at scale.
𝐀𝐒𝐆𝐂𝐓 𝟐𝟎𝟐𝟓: @Dyno_Tx's CEO Eric Kelsic discusses the latest in capsids for CNS, ophthalmology, and neuromuscular conditions. #ASGCT2025
Full video: https://t.co/KJm1rHm09q
$DTIL discloses additional safety data today at #ASGCT25 for in-vivo gene editing trial targeting Hepatitis B.
Appears that they are ~4 weeks past the first patient dosed in cohort 2 (0.4 mg/kg). Safety remains in-tact for this patient and the three cohort 1 patients (0.2 mg/kg).
$DTIL has stated that they plan to share initial efficacy data ~a month after all three doses are concluded in each cohort. Should see this initial view into efficacy in July by my math...
👉 https://t.co/hg9nBiXaIe
Amazing work Ko-Wei Liu and the collaborative team to engineer CAR T cells where persistence is controlled by leveraging @CueBiopharma recombinant ImmunoSTATs to specifically deliver TCR+cytokine signals to our engineered cells. #asgct25 #asgct2025 @DanaFarberNews
Congrats @EJBrea on awesome work and an awesome presentation showing how CAR T cell therapy can overcome ADC resistance in solid tumors and engineering rational biparatopic CARs. #asgct2025 #asgct25 @DanaFarberNews
Congrats @LizCarstensMD on your outstanding presentation on engineering novel CARs to enhance the therapeutic window of CAR T cells for GI malignancies. #asgct2025 #asgct25 @DanaFarberNews
@TheCryptoMaze @SangamoTx @ASGCTherapy All $SGMO posters and presentations from #ASGCT2025 #ASGCT25 are online:
https://t.co/tqAhNH3bRw
@ASGCTherapy @SangamoTx
Today at the #ASGCT25 Dyno Symposium we announced the launch of three exceptional new capsids for gene delivery to the CNS, eye, and muscle: Dyno-ahq, Dyno-4z2 and Dyno-3hv.
You can learn more about these capsids and partnering with Dyno at https://t.co/guwEjYA5v7, and as summarized here: https://t.co/7teAAIwdZH
We are back exhibiting at this years annual American Society of Gene & Cell Therapy meeting, @ASGCTherapy! You can find us at booth # 1751 with samples of our newest DNA and RNA transfection reagents. We are in New Orleans until this Friday!
#ASGCT25 #FuGENE
Join us tomorrow at #ASGCT25 for a presentation on the data behind Dyno’s newest CNS vector: an AI-designed AAV capsid optimized for widespread IV delivery to the brain, with exceptional liver detargeting and a highly conserved mechanism for blood-brain barrier crossing.
►Presenter: Mugdha Deshpande, Ph.D.
►Date and time: Wednesday, May 14, 2025, 1:30 PM – 1:45 PM CT
►Location: New Orleans Theater C
►Abstract number: #88
TOMORROW: Join us at this year’s #ASGCT25 Dyno Symposium! Dyno CEO & Cofounder Eric Kelsic will share data on leading-edge AAV capsids, the frontier AI models behind their design, and how Dyno supports partners rapidly advancing next-generation gene therapies into the clinic.
Pick up our special bumper May issue @GENbio devoted to cell+gene therapy —as well as @CRISPRjournal @HGTJournal @LiebertPub @Sage_Publishing !
Booth 1350 #asgct25 #asgct2025
If you're attending #ASGCT25 don’t miss our presentations on capsid engineering, gene editing, and manufacturing. Our researchers are laying the groundwork for future precision heart medicines. Full press release: https://t.co/lfemx7FOKW
#GeneTherapy #HeartHealth
@Franca_ole @SangamoTx Q1 won't shine—#Capsid x $LLY closed in first hours of Q2. Without fresh news, the call may lean negative. Still, updates could drop as early as Monday. Either way, #ASGCT25 should deliver exciting science in particular oral Presentation on #Prion on Wednesday. $SGMO
ASGCT: CRISPR-Cas12 Editing Shows Early Clinical Benefit in Duchenne Muscular Dystrophy
@HuidaGene is also working on a CRISPR-based RNA editing treatment for neovascular age-related macular degeneration.
.
@AlvinLuk_Health @ASGCTherapy #CRISPR #ASGCT25
https://t.co/9pHwV7TdEF
We’ll have SIX posters at #ASGCT 2025! From #HDR efficiency to #CRISPR library design solutions, IDT scientists will cover a wide range of valuable topics you won’t want to miss. More details: https://t.co/LAeDJfwIMW
#ASGCT2025 #ASGCT25
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