Top Tweets for #Alk5
Fibrous optics improving in CD as Agomab mulls phase IIb https://t.co/ogrPRkXdG2 #biopharma #alk5 #Crohns
A 83-01 is a potent inhibitor of #TGFβ type I receptor #ALK5 kinase, type I nodal receptor #ALK4 and type I nodal receptor #ALK7, with IC50s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5, ALK4 and ALK7, respectively. #drugdiscovery. https://t.co/doSmMcGo46
@Mangan150 @SatchinPanda @geochurch @PNASNews @npure3 @rhg_1 @drareimers @Drlipid @davidasinclair Think they used an «#Alk5 inhibitor» that Conboy et al also recently showed could reverse multiple symptoms of aging (together with #oxytocin): https://t.co/SK7DeFdX5x…
(Alk5 inhibitor reducing TGFβ/ALK5/pSmad 2,3 & Oxytocin inducing MAPK/pERK signaling.) #Antiaging
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