#ChREBP - Twitter Hashtag

9 months ago

#Throwback. Earlier this year we showed how #glucose and #fructose rich diets activate #ChREBP excessively to induce hepatic “mixed” insulin resistance, providing the gateway for development of #MASLD and type 2 #diabetes. See https://t.co/c9VBIZ7Zo0

pjthornalley's tweet photo. #Throwback. Earlier this year we showed how #glucose and #fructose rich diets activate #ChREBP excessively to induce hepatic “mixed” insulin resistance, providing the gateway for development of #MASLD and type 2 #diabetes. See https://t.co/c9VBIZ7Zo0 https://t.co/r0JbICOcpm

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Nature Metabolism

@NatMetabolism

10 months ago

RESEARCH | @CharlesMBrenner et al (@cityofhope) In a mouse model of #CitrinDeficiency, accumulation of glycerol-3-phosphate leads to ChREBP activation and #FGF21 induction, identifying glycerol-3-phosphate as a #ChREBP-activating ligand https://t.co/fLdM93ZJvP

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Paul J Thornalley @pjthornalley

over 1 year ago

@NutrioSci As the liver receives ca. 50% dietary simple #sugar, glycolytic overload likely involved - also stimulating lipogenesis through increased #ChREBP activity. Early-stage treatment by @Glo1inducer supplement diverting excess G6P into PPP etc? See https://t.co/TPjEzI8AjM #MASLD

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Molecular Oncology @MolOncology

over 2 years ago

😴Did you miss it? ➡️New Commentary by Matías Avila & @MaiteGF_B Sweet dreams could be made of this: carbohydrate-responsive element-binding protein (ChREBP) as a target for hepatocellular carcinoma therapy 🔓https://t.co/PPHS0D58pz #LiverCancer #ChREBP #CancerMetabolism

MolOncology's tweet photo. 😴Did you miss it?

➡️New Commentary by Matías Avila & @MaiteGF_B

Sweet dreams could be made of this: carbohydrate-responsive element-binding protein (ChREBP) as a target for hepatocellular carcinoma therapy

🔓https://t.co/PPHS0D58pz

#LiverCancer #ChREBP #CancerMetabolism https://t.co/r2qzBFmFf9

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Nature Reviews Endocrinology @NatureRevEndo

over 2 years ago

This Review from Catherine Postic and colleagues discusses mechanisms that regulate #ChREBP activity, the role of ChREBP in #NAFLD and emerging NAFLD drug targets (£) https://t.co/YhOvvGg35R

NatureRevEndo's tweet photo. This Review from Catherine Postic and colleagues discusses mechanisms that regulate #ChREBP activity, the role of ChREBP in #NAFLD and emerging NAFLD drug targets (£) https://t.co/YhOvvGg35R https://t.co/zsjtXdTUmj

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Liora Katz @LioraKatz1

over 2 years ago

Exciting findings from our recent preprint on #ChREBP and #Type2Diabetes! Small molecule treatments targeting ChREBPα/14-3-3 interaction, offering hope for novel therapeutic avenues. 🧬 #MetabolicHealth #Research. Full text is now available: https://t.co/hkyBpmoQeq

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Dentin renaud @DentinRenaud

over 2 years ago

Excited to share our latest work on the contribution of the transcription factor ChREBP to HCC initiation and development in Nature Communications (@NatureComms). https://t.co/PbwAQjtcGA. #CancerTreatment, #ChREBP, #metabolism. 1/3

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Fawaz Alzaid, PhD, HDR

@DrFAlzaid

almost 3 years ago

Latest curated papers👇🏽 📷#JOINTLY: interpretable joint clustering of #singlecell transcriptomes 📰#ChREBP is activated by reductive stress and mediates GCKR-associated #metabolic traits. 🎲#Neutrophils only die twice 🔗https://t.co/oRmhc0vbz4 🙏🏽Thx @Bims_BiomedNews

DrFAlzaid's tweet photo. Latest curated papers👇🏽
📷#JOINTLY: interpretable joint clustering of #singlecell transcriptomes
📰#ChREBP is activated by reductive stress and mediates GCKR-associated #metabolic traits.
🎲#Neutrophils only die twice
🔗https://t.co/oRmhc0vbz4
🙏🏽Thx @Bims_BiomedNews https://t.co/i6fE3wMvOi

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Nature Reviews Endocrinology @NatureRevEndo

over 3 years ago

In our June issue: Catherine Postic and colleagues discuss the mechanisms that regulate #ChREBP activity, the role of ChREBP in #NAFLD and emerging NAFLD drug targets (£) https://t.co/YhOvvGfvgj

NatureRevEndo's tweet photo. In our June issue: Catherine Postic and colleagues discuss the mechanisms that regulate #ChREBP activity, the role of ChREBP in #NAFLD and emerging NAFLD drug targets (£) https://t.co/YhOvvGfvgj https://t.co/5tOO4ozfVX

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Nature Reviews Endocrinology @NatureRevEndo

over 3 years ago

The June issue of @NatureRevEndo is now live! It includes articles on #glucagon, #ChREBP, models of #diabetes and treatment of #T1DM https://t.co/Atja3RzWdE

NatureRevEndo's tweet photo. The June issue of @NatureRevEndo is now live! It includes articles on #glucagon, #ChREBP, models of #diabetes and treatment of #T1DM https://t.co/Atja3RzWdE https://t.co/ZUDnFjUDPk

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まさぼ@糖尿病&抗加齢医学専門医 @masabo_DM

over 3 years ago

果糖の過剰摂取は ChREBPの発現充進を介して肝臓での脂肪合成システムを充進させることもわかりました。 #ChREBP #脂肪合成 #肝臓 #果糖

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まさぼ@糖尿病&抗加齢医学専門医 @masabo_DM

over 3 years ago

果糖摂取による脂肪合成の充進は ✔️ChREBPと呼ばれる転写因子の発現充進と ✔️肝臓へのアセチルCoAの供給の 2つのメカニズムが合わさることで引き起こされることが明らかになりました。 #脂肪合成 #肝臓 #アセチルCoA #ChREBP

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P-D Denechaud @DamienDenechaud

over 4 years ago

ChREBP-Bat-KO: #ChREBP-regulated #lipogenesis is not required for the #thermogenesis of brown adipose tissue https://t.co/hsbsTMFWaE

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AJP-Endocrinology and Metabolism @AJPEndoMetab

almost 6 years ago

In Press: #NewResearch suggests that #ChREBP prevents the uptake of glucogenic amino acids upon consumption of a high-carbohydrate diet: https://t.co/4nFkhYBT0P #SNAT2 #aminoacidtransport #highcarbohydratediet #SMRT