Top Tweets for #Importins
🚨📝New review alert! @MolNeuro
Great collaborative effort between @Rossolllab and @ShorterLab! #Importins #RBPs #PhaseTransition #ALS #FTD
'Nuclear-import receptors as gatekeepers of pathological phase transitions in #ALS/#FTD'
@DrBilalKhalil @M_Linsenmeier @neuro_smith @ShorterLab @RossollLab @MayoClinicNeuro @PennMedicine #TDP43
https://t.co/fC2KEfgYG2

Nuclear transport is a key biological process regulated by post translational medications of cargoes. In this work we elucidated the atomistic details of how cargo phosphorylation can negatively impact nuclear import #research #importins #FEBS #Unipd #DMM https://t.co/JFvjAE2PWL
Latest curated articles👇🏽
📰Negativity begets longevity in #Tcells(📷)
📰Co-translational binding of #importins to nascent proteins
🧠Clonal hematopoiesis is associated with protection from #Alzheimers disease.
🔗https://t.co/5DBxmWdJbi
🙏🏽Thx @Bims_BiomedNews

Work by Max Seidel, @NatalieRomanov, @aobarska and others showing that #Importins bind to nascent nuclear proteins at the exit tunnel of the #ribosome now online @NatureComms. Great collaboration with V Benes @embl. #proteostasis #RNA #nuclearimport @mpibp
https://t.co/q8WOlzcaQ8

Thrilled to share my work on the role of import receptors in reversing TDP-43 proteinopathy. Thanks to all the authors who helped get this beautiful story out! @MolNeuro @RossollLab #Importins #TDP43 #PhaseTransition #ALS #FTD
'Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 #proteinopathy'
#ALS #FrontotemporalDementia
@RossollLab @_BilalKhalil_ @Dkchhangani @NeuroWren @neuro_smith @jannafur @MayoClinicNeuro
https://t.co/yg9wSaCPyH

(2/6) Selective ribosome profiling (SeRP) of all yeast #importins identified many novel cargos (e.g. #chromatinremodelers, ribosome biogenesis factors and nucleic acid binders). SeRP curves reveal the onset of importin binding during protein biogenesis.

(1/6) Did you know that #importins bind to nascent chains of their cargos at the #ribosome? Work by Max Seidel @NatalieRomanov and others from @Beck_Laboratory @MPIbp and @embl Genomics Core Facility now online. #proteostasis #RNA #nuclearimport
https://t.co/yRK2NWqaVY
Another study confirming the importance of #importins in the #CNS! This time KPNA3 (aka human Importin α4). Hope to be able to re-launch some studies (in the near future?) on these mice that I screened few years ago!! https://t.co/NnrvS9pzKJ
**The #importins of pain https://t.co/1FsVvt6JZ9
#pain => #chronicpain #neuropathicpain #transcription #nucleocytoplasmictransport #cFos #AP1 #transcriptionfactor #analgesia #drugtarget #Importinα3 #Syngap1
FULL Report: https://t.co/5aWCnqeUfw @ScienceMagazine

Now published @ScienceMagazine https://t.co/39W6hHk5JX I would like to say congrats and thanks to my friend and office mate @LetiziaMarvaldi, @MFainzilber and *all the authors* in this adventure. It has been a pleasure to fight for this! #Importins are Important..also in #Pain
Nuclear import mechanistic clues that might help in the future fight viruses from great structural biology presented by @KatMarLouSmi #AsCAnz #crystal32 #AsCA2018 #nuclearimport #importins #crystallography #virus #nepah #wprotein #hendra https://t.co/DAPvupGVhS

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