Top Tweets for #LIBRETTO431
📢 Our report of #Asian subgroup data of #LIBRETTO431: #selpercatinib vs. #ChemoIO #firstline treatment in #RET_FusionPositive #NSCLC 🫁 has been published in @IASLC #JTOCRR. 54% of this global trial were from #EastAsia 🌏.
Results consistent with #overallpopulation and further echos the importance of early identification through molecular profiling in #Asia.
Full paper can be found here: https://t.co/OysP8GNBCu
@EliLillyandCo @CUHKMedicine @apoddc @APCLC_2023 #drugdevelopment
#ESMO23 Lung II Highlights w/ @AlexSpiraMDPhD
- #PAPILLON
- #MARIPOSA
- #MARIPOSA2
- #LIBRETTO431
Full 📢:
- https://t.co/UoegMXkdPK
- https://t.co/IJYYXsTfq9
- Also on the “Oncology Brothers” podcast
GI to follow!
#MedTwitter #OncTwitter @myESMO #lcsm #LungCancer
Cause-specific HR for time to progression affecting CNS was 0.3 (95CI 0.1-0.7) on #LIBRETTO431
This HR in not applicable to the USA population without clarity on who had an initial MRI brain.
We can do better and need to hold @NEJM accountable for omitting this information.
Is there any data on the percentage of patients who received MRI brain at baseline on #ALINA & #LIBRETTO431?
This should be standard reporting on all trials, especially international trials where the target market for profits is the USA, where MRI brain is the standard of care.
#ESMO23 Presidential 1
THE LungCancer story ♥️
- PAPILLON ✅
- ALINA ✅
- LIBRETTO 431 ✅
- CheckMate77L ✅
What else?! 🔥
@DoctorJSpicer @HHorinouchi @myESMO @bensolomon1 @FordePatrick @MARIANOPROVENCI @BrendonStilesMD @DrewMoghanaki Hey! What happened to #LIBRETTO431? 😂😂😂 Congrats all for your leadership!
#ESMO23 Day2 ⚡️🔥 #CommunityOncology
1. DB04 ⬇️Her2 #bcsm
#NSCLC
2. #ALINA ALK+ @bensolomon1
3. #LIBRETTO431 RET+
4. #PAPILLON Exon20
5. #CM77T ✂️
6. #LITESPARK005 Belzutifan-RCC @DrChoueiri
7. #SPOTLIGHT Cldn18.2 #gism
#OncTwitter #MedTwitter @myESMO #lcsm
1/8
@herbloong presenting #LIBRETTO431 #Selpercatinib in frontline advanced non squamous NSCLC #ESMO2023 #practicechanging ! Check for #Drivermutations #PrecisionLung !
🔥🚨@OncoAlert Hot off the press.
Just published @NEJM in conjunction with presentation @myESMO #ESMO23.
“Results of #LIBRETTO431; Phase 3 trial of 1st line #Selpercatinib vs #Chemotherapy +/- #Pembrolizumab in #Patients with #RET positive #NSCLC.
👇🏼
https://t.co/1go7SEuB3e
#ESMO23… or more like #FOMO23 for this thoracic oncologist? @myESMO @OncoAlert 🤯 🫁
Resectable NSCLC
▫️#CM77T
▫️#KN671
▫️#ALINA
Advanced NSCLC
1L:
▫️#LIBRETTO431
▫️#PAPILLON
▫️#MARIPOSA
2L+:
▫️#MARIPOSA2
▫️#TROPIONLung01
< 3 weeks to #ESMO23, here is a📝 of 🔑abstracts for general onc that could change our SoC!
- #ALINA
- #LIBRETTO431
- #TROPIONLung01
- #MARIPOSA
- #Ev302
- #CM901
- #LITESPARK005
- #KN756
- #CABINET
- #CODEBREAK300
#BCSM #GISM #LCSM #MedTwitter #GUSM #OncTwitter @myESMO
< 3 weeks to #ESMO23, here is a📝 of 🔑abstracts for general onc that could change our SoC!
- #ALINA
- #LIBRETTO431
- #TROPIONLung01
- #MARIPOSA
- #Ev302
- #CM901
- #LITESPARK005
- #KN756
- #CABINET
- #CODEBREAK300
#BCSM #GISM #LCSM #MedTwitter #GUSM #OncTwitter @myESMO
LIBRETTO-431 shows first line selpercatinib provides longer PFS than chemo-immunotherapy in #RET fusion positive NSCLC. Await full data but no surprise. Selective RET inhibitors are among the more effective and better tolerated targeted agents in NSCLC.
https://t.co/GU4gbmsOKb
Great news for #RET+ #NSCLC patients! The phase III study #LIBRETTO431 hit its primary endpoint. Selpercatinib boasts statistically superior PFS vs PD-1 +CT for RET+ NSCLC. Advancing the power of #precisionmedicine .Comprehensive genomic testing is KEY in NSCLC.🎯@OncoAlert
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