Top Tweets for #LiquidLiquidPhaseSeparation
Hierarchical Porous Microsphere as Endothelial cell + Mesenchymal stem cell carrier to treat🐭#LimbIschemia
Pig small intestine decellularized matrix + GelMA
+PEO #LiquidLiquidPhaseSeparation➡️Primary pore 40 μm
+Ice templating➡️Secondary pore
+Fibronectin functionalization
Microsphere 200 μm diameter
>90% porosity
@BioactiveMat 2026
https://t.co/O6N7yif1uj
#LiquidLiquidPhaseSeparation #Heterochromatin
CK2-dependent N-term Ser11-Ser14 phosphorylation & basic segment b4 (K68-K72) of HP1α is critical for its LLPS & heterochromatin assembly
Yoshifumi Nishimura lab @NAR_Open 2025
https://t.co/GCwkUT5Ddd
Deactylation by SIRT1 enables #LiquidLiquidPhaseSeparation of IRF3/IRF7 in innate antiviral immunity
"Site-specific acetylation of IRF3/IRF7 DNA-binding domain abrogates LLPS"
"Reinforcing SIRT1 activity rescues innate #Immunosenescence" (HSV-1, SeV, VSV)
@NatImmunol 2023
https://t.co/gnUXcAnYzA
My continued biological education
#LiquidLiquidPhaseSeparation
Phase separation as a new form of regulation in #InnateImmunity
Sensor-Adaptor-Transcription factor-Effector
DNA sensing cGAS-STING-IRF3
RNA sensing PKR
Inflammasome NLRP6
Ubiquitination (TRIM5α, NEMO)/SUMOylation (MAVS) confers liquid properties
Cyclic Nucleotide-based antiphage signaling system
Lei Wang, Wen Zhou @MolecularCell 2024
https://t.co/D20dmx2gkz
Our most recent paper on a new application of biomolecular condensates: a label-free, easy
to implement and fast method to detect E. coli (and potentially other bacteria). #coacervates. #LiquidLiquidPhaseSeparation
#LLPS
@BioCondensates
https://t.co/Jr3gzLDmup
#BiomolecularCondensates/#LiquidLiquidPhaseSeparation/#phaseSeparationCoupledToPercolation - what are the challenges, excitement, and opportunities? I'm grateful for the feedback of these experts! Check out what they wrote in our latest Viewpoint at NCB
https://t.co/XtfCh6MtZA
☕️New Viewpoint Article:
We asked experts to comment on what excites them most regarding biomolecular condensation, as well as on current challenges, priorities and needs for the functional study of condensates.
PDF: https://t.co/acPDn6xf6k
https://t.co/XEoAVdLMTh
@KamounLab @INRAE_Tlse @TULIP_GS_LabEx Sophien, to follow up on the #LiquidLiquidPhaseSeparation, it seems that nucleation (of the nascent resistosome) itself could generate a phase separation within the cell. Could it exclude other helper NLRs to get involved in the newly formed resistosome ?…
Now my #dynamic #friend @jrkumita who is starting w a #scientific #tour of her unconventional #careerpath from #amyloid to #liquidliquidphaseseparation #LLPS #biomolecular #condensates in #autophagy #stressresponse #membranelessorganelles #aggregates #droplet #structure #CTPR
α-#Synuclein #PhaseSeparation and #amyloid aggregation are modulated by C-terminal truncations
➡https://t.co/Jvr39DSQK6
#neurodegeneration #LiquidLiquidPhaseSeparation #synucleinopathies #neurodegenerativediseases
A new study led by Yoshimura: Cell cycle-regulated phosphorylation of Ki-67 and NPM1 modulate alternating charge blocks in these proteins, which defines their propensity for #LiquidLiquidPhaseSeparation at chromatin.
PDF: https://t.co/xx9Cp9k1h3
https://t.co/H8ZkkzTIcM
How are m6A-modified bases in mRNAs regulated? @KosikLab shows that cells can use #LiquidLiquidPhaseSeparation to regulate dynamic assembly of the mRNA m6A methyltransferase complex; stoichiometry depends on substrate-specific partitioning #PLOSBiology https://t.co/Un7rG8hrbj
How are m6A-modified bases in mRNAs regulated? @KosikLab shows that cells can use #LiquidLiquidPhaseSeparation to regulate dynamic assembly of the mRNA m6A methyltransferase complex; stoichiometry depends on substrate-specific partitioning #PLOSBiology https://t.co/Un7rG7ZQjL
How are m6A-modified bases in mRNAs regulated? @KosikLab shows that cells can use #LiquidLiquidPhaseSeparation to regulate dynamic assembly of the mRNA m6A methyltransferase complex; stoichiometry depends on substrate-specific partitioning #PLOSBiology https://t.co/Un7rG7ZQjL
Thanks Collepardo lab @rcollepardo for an amazng night of joint talks @pantonarms1! And thanks @StanStrawbridge and @MaikeSteindel for some lovely talks from our end! Can't wait to do it again some time. Lots to think about...#liquidliquidphaseseparation #chromatin
Rainy day at @Cambridge_Uni ? Why not have pub talks with @srinjan_basu and @rcollepardo labs @pantonarms1? #liquidLiquidPhaseSeparation #chromatin
[Account/Review]
Liquid-liquid phase separation | Biomolecular condensates | Intrinsically disordered region
Review by Prof. Motomu Kanai @kanailab (The Univ. of Tokyo) is available as Open Access
#LiquidLiquidPhaseSeparation #LLPS #BiomolecularCondensates
https://t.co/bEtTQksSYS
![CSJjournals_jp's tweet photo. [Account/Review]
Liquid-liquid phase separation | Biomolecular condensates | Intrinsically disordered region
Review by Prof. Motomu Kanai @kanailab (The Univ. of Tokyo) is available as Open Access
#LiquidLiquidPhaseSeparation #LLPS #BiomolecularCondensates
https://t.co/bEtTQksSYS https://t.co/yXZtrIzwxU](https://pbs.twimg.com/media/FDFLrv-UcAYLtaU.jpg)
Cells recognize osmotic stress through macromolecular crowding-driven and poly(ADP-ribose)-conditioned #LiquidLiquidPhaseSeparation
https://t.co/JrO0toVcwo
Cells recognize osmotic stress through macromolecular crowding-driven and poly(ADP-ribose)-conditioned #LiquidLiquidPhaseSeparation
https://t.co/JrO0toVcwo
To further explore the universe of #biomolecularcondensates see this Collection of #Reviews, journal clubs and selected research articles @NaturePortfolio highlighting recent progress in mechanisms and roles of #LiquidLiquidPhaseSeparation in biology
https://t.co/xog6aCtEpR
@NatRevMCB FOCUS on #LiquidLiquidPhaseSeparation
Roadmap by Mike Rosen and co: A framework for understanding the functions of #biomolecularcondensates across scales
@a_s_lyon @UTSWNews
https://t.co/tFxhDPvfiB
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