Top Tweets for #LocallyAdvanced
Randomised (non-conparative) study #LocallyAdvanced #PDAC at @myESMO #ESMOGI26
👉FOLFIRINOX
👉FOLFIRINOX + P-32 EUS-guided brachytherapy (100Gy)
Similar local disease control (1ry end-point) and resection rate
BUT, may improve PR, R0, PFS and OS (see comment)
#ESMOAmbassadors

🔥🚨 @OncoAlert Hot off the press.
As expected, @US_FDA approves #Osimertinib for #locallyadvanced #EGFR+ #NSCLC following concurrent or sequential #Chemoradiation.
Approval based on #Laura trial:
⬆️#mPFS 39.1 (Osi) vs 5.6 months (placebo). HR 0.16
👇🏼
https://t.co/J1bZQmQPlO

Incoming ✈️ #ESMO24 data from @tompowles1 on #PFS and #OS benefit with #EVplusPembro in #metastatic #locallyadvanced #urothelialcarcinoma across all #subgroups.
🧠 Learn more: https://t.co/IWDxj09gip

Novel approaches to #locallyadvanced landscape for #NSCLC including #CCRT #immunotherapy expertly discussed by the fabulous @ChristineBestv1 from @UCCancerCenter at the #IULungSymposium
#LCSM #EndLungCancerNow @IUCancerCenter @IUPUI @gdurm @BigTenCRC

#polltime
⁉️Do you employ neoadjuvant therapy for #locallyadvanced colon cancer? Share your approach
#neoadjuvanttherapy #cancertherapy #SoMe4Surgery #MedTwitter #SurgEd #Surgery @RCPSGTrainees @aecirujanos @SEIQuirurgica @iss_sic #MedicalTechniques @BJSAcademy @young_bjs @BJSOpen @des_winter @evanscolorectal @robhinchliffe1 @bplwijn @ksoreide @MalinASund @nfmkok @TejedorPat @paulo_sutt @PVaughanShaw @JJEarnshaw @juliomayol @asgbi @ESCP_tweets @YouESCP
Interesting review on #borderlineresectable and #locallyadvanced #PDAC
📑 considerable variation in international #guidelines
🕳️ lacking of randomised controlled trials for #preop approach
🩻need of integration of #biological and #imaging response
https://t.co/MyY7iBhgmO
Check out newly released @FoxtrotStudy mature results @ASCO @JCO_ASCO ✨
NAC safe and effective for #locallyadvanced #CRC @me4_so
Will this change practice in your unit? 💊
@JenSeligmann
Our FOxTROT-1 mature results have just been released! @JCO_ASCO
Preoperative chemotherapy is a safe and effective treatment option for locally advanced #coloncancer 💊
Huge thanks to @CRUKresearch @yorkshirecancer and all our international collaborators! 👏

🔴The crucial question for #pancreaticcancer #prognosis is still "Is it resectable? " but criteria are debated and frequently updated 🤔🤔
This interesting #retrospective experience tries to identify more complete criteria in the #LocallyAdvanced stage👇
In the modern era neoadjuvant with multi agent therapy, radiographic response can be achieved 20-30% of time. In this series locally advanced pts were able to undergo resection 16% of time. @AnnSurgOncol @McMastersKelly @DavendraSohal @kharofaJ @TsengJennifer @RSnyder_MD
The Next @YSAC_PK online #SurgicalOncology #JournalClub will be held on Saturday 13 August 2022 5pm PKT [08:00 New York, 13:00 London, 14:00 Brussels, 21:00 Tokyo] discussing Real world outcomes of #LocallyAdvanced #BreastCancer
@SOS_Pk @PkSurgeons
https://t.co/anW3ZFvEPE
Options for #locallyadvanced rectal cancer & LRRC which invades or abuts the sacrum #carefulplanning #teamwork #QOL #rehab @StMarksHospital

While the data from KN-799 is intriguing, it does not replace the current standard of care currently.
I remain intrigued at the possibility of using systemic dose chemotherapy with earlier integration of Immunotherapy in patients with #LocallyAdvanced #NSCLC #LCSM

The #IBC community faces this as well. We're usually thrown in with #locallyadvanced #breastcancer or just #metastaticdisease but IBC outcome may not be the same. Too few ppl to have meaningful data. #OpportunityLost Thanks for speaking up.
Patients with #Metastatic #lobular #breastcancer have long suspected this - we must FIX this to give patients access to trials and to study #ILC and learn differences. Thx @UCSFCancer @hoperugo and Rita Mukhtar for this research
@LobularBCA
@ASCO2021
@mbcalliance
@OncoAlert
Wonderful news for patients and field. Kudos to trial volunteers who paved the way for future generation. Lot more needs to be done to further improve #MBC outcomes, including accelerating development of effective therapies and rational mechanistic-based combinations.#oncoalert
Great new addition on #LocallyAdvanced #PancreasCancer in Europe. Hard to determine who is best suited for the aggressive regimens, but those who complete have improved #Survival @PanCAN_Oklahoma @UticaParkClinic
Locally advanced #PancreaticCancer prospective study in all-comers: 14 🇳🇱 centers, 422 pts; 77% chemo of whom 77% FOLFIRINOX. mOS entire cohort 10 months, FOLFIRINOX 14, gem-nab-paclitaxel 9. Resection after FFX: 13%, mOS 23 months. https://t.co/UShBwjFXJT #alvleesklierkanker

National neoadjuvant #PancreaticCancer MDT @grisurgery today. Fantastic to have the #hpb teams from across Scotland @EdinSurg, Dundee, Aberdeen, Inverness. great cases great discussions. @precisionpanc #locallyadvanced @ewenharrison @DamianJMole @AdairAnya @rravindran1

If tomorrow morning you fall off the bed at #EAHPBA2019 and fancy #freebreakfast together join us discussing #irreversibleelectroporation in #locallyadvanced #pancreaticcancer #IRE #LAPC #BRPC @PancreaticCanUK @JacksonLinds @V111NOS

Promising day spent in London finalising plans for an imminent feasibility #trial for #irreversibleelectroporation in #locallyadvanced #PancreaticCancer. A collaborative #UK study. Thanks to @PancreaticCanUK for its continue support @praveenpeddu @V111NOS #IRE #LAPC

Thanks @eileen_parkes.
Great to see Ian laying out synergy of #CancerMetabolism & targeted #TumourLethality
Critical mass of #Basic_Science & #Clinician_Scientist #PIs in #Oxford to now dig deep into #HighRisk & #LocallyAdvanced #ProstateCancer
#PCFLondonSummit19
@PCF_Science
Congrats co-chair Nelson Yee, @PennStHershey Cancer Inst. on @ASCOPost guidelines #LocallyAdvanced #PancreaticCancer https://t.co/EtvSjd1LqF
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