Top Tweets for #LoiLab
๐ฉ๐ฉlatest from the #loilab
"Germline BRCA1 pathogenic variants and T cell dysfunction" https://t.co/7aGabWZvkm
Weโve traditionally viewed BRCA1 as a tumour suppressor acting within epithelial cells.
Our study suggests germline BRCA1 pathogenic variants may also impair host T cell function, providing a new perspective on hereditary breast cancer biology.
congrats ๐๐ Jasmine Kay @PeterMacRes @OncoAlert #bcsm
๐ฉ๐ฉlatest research from the #loilab
We studied in a prospective randomized trial if single vs multi fraction SABR+ Atezo was effective in patients with advanced #TNBC in an era prior to routine pembrolizumab.
๐๐Congratulations to @drspdavid @pssavas
thank you ๐to the patients and families, TROG, @PeterMacRadOnc @PeterMacCC @NatureComms @Roche @genentech
#bcsm @OncoAlert
https://t.co/aKdLqDA43c
โจโจhot off the press from the #loilab. We show here that pregnancy & breastfeeding is associated with increased T cells in the normal breast and protection against #tnbc #breastcancer moving the role of immunity from treatment to prevention.
๐๐Thanks to @FAndreMD @DrChoueiri @MyriamChalabi for the opportunity to present #ESMO25 @OncoAlert @myESMO
@PeterMacRes @PeterMacCC @UniMelb
thanks to our funders @BCRFcure @TheMarkFdn @NBCFAus
@Nature Article is here: https://t.co/pu3STvXvm1
Translational data shows that #breastfeeding helps personal immunity improving CD8+ T
This work can help to understand better the immune system and breastfeeding mechanisms @LoiSher @OncoAlert #ESMO25 @FernandoOnco
โก๏ธNew from #loilab
๐ฉ๐ฉOur new study shows higher baseline tumour burden predicts poorer outcomes on #immunotherapy in metastatic #breastcancer.
๐ฉWhy this matters: maybe surveillance post early #TNBC is now ready for prime time- if ultrasensitive ctDNA can detect relapse months before imaging, we can treat at low volume, when ICI may work better. #ctDNA #LiquidBiopsy #BreastCancerAwareness
๐๐๐congrats @J_DixonDouglas ๐คฉ
@PeterMacRes @PeterMacCC @oncoalert #bcsm
https://t.co/MpOklAgqDi
๐latest review from #loilab & our Spanish colleagues #vhio #bcsm @OncoAlert @TILsWorkGroup Biomarkers of response and resistance to immune checkpoint inhibitors in breast cancer https://t.co/uPyCsREPRp
Bidding farewell & good luck ๐ to @GeukensTatjana going back to @Onco_KULeuven who are v. lucky to have her! thanks for lending her to us #loilab @ChristineDesme2 @PeterMacRes #bcsm
๐ฉ๐๐ฉ new from #loilab @ranli01
1/3 Tucatinib promotes immune activation and synergizes with programmed cell deathโ1 and programmed cell deathโligand 1 inhibition in HER2+ #breastcancer #bcsm @oncoalert #HER2 @PeterMacCC @SeagenGlobal
https://t.co/S856nesWNZ
Hey ๐ #bcsm #ASCO2023 #ASCO23 Upcoming oral early #breastcancer session by #loilab @etop_ibcsg 2.45pm hall D1 โก๏ธ is PAM50 ROR prognostic In premenopausal HR+ BCโ
๐ฉ๐๐ฉ hi everyone, latest from the #loilab- happy weekend! @OncoAlert #bcsm @TILsWorkGroup @PeterMacRes @PeterMacCC
Shout out to @KarantzaValia & our longstanding TIL biomarker colloboration with @Merck -more to come hopefully ๐
https://t.co/krAzGoVLCL
๐ฉโก๏ธPleased to share our latest review on #breastcancer & #immunotherapy with #leishaemens
Free thanks to Cold Spring Harb Press ๐๐ @CSHLPress
#bcsm @OncoAlert @PeterMacCC @PeterMacRes @etop_ibcsg #loilab
https://t.co/tuGMu9dl0P
๐๐ฉบ
Super excited to be part of this amazing issue & on the cover! Thanks @Montse_Rojo_PhD @Cancer_Cell Art by @maja_divjak @PeterMacCC #loilab @PeterMacRes #bcsm thanks again to our collaborators @LMackayLab @GBG_Forschung @CharlesSwanton &funders @nhmrc @NBCFAus
We are very proud to present our 2023 Special Issue dedicate to a holistic view of cancer! With 10 Reviews, a Perspective, and our Editorial, we lay out what we see as the future for impactful cancer research. You can read it now: https://t.co/ssfPwLsJDh
Thank you @NatureCancer for supporting our work #loilab @amy_winship @HuttLab #IWD2023 #WomenInScience #WomenInSTEM @PeterMacRes
Happy International Women's Day #IWD2023 !
@NatureCancer supports #WomenInScience - please join us to celebrate some of the wonderful female scientists & clinicians who recently published their work with us โ we hope you are inspired by them! ๐ฉโ๐ฌ
๐โก๏ธ excited for our latest from the #loilab #TIL #bcsm @OncoAlert @PeterMacRes @PeterMacCC @UniMelb
1. Here we are investigating #breastcancer #TCELL subsets. We have previously identified a T cell resident memory phenotype (TRM) in human #TNBC which stay in the local TME
Online Now: Intratumoral CD8+ Tย cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer https://t.co/Usl0t8Cy2T
4) We also thank ๐๐๐ @SusanGKomen @NBCFAus @BCRFcure @nhmrc @etop_ibcsg & funders of the #SOFT study #loilab @PeterMacRes @PeterMacCC
#Loilab Christmas party- thanks to a great team for a great yearโฆ lots more exciting things to come for #breastcancer research next year ๐ to all our funders @NBCFAus @BCRFcure @nhmrc @PeterMacRes @PeterMacCC @UniMelb #bcsm
Check my PhD studentโ poster P5-02-16 on SPEN mutations as a biomarker of CDK4i resistance- as well as a scholar in training award! ๐๐๐#bcsm @OncoAlert @PeterMacRes #SABCS22 #loilab
Hanging out with my lab #loilab @ResAustralia award night- ๐๐๐๐congrats to all the winners #ResAusAwards thanks to @NBCFAus @PeterMacRes @PeterMacCC for the nomination!
Fantastic to meet @NatHutchins and many+++ ๐๐๐พ๐ฅ amazing women at #honorher #Vicforwomen @WomenVictoria many thanks to @PeterMacCC @PeterMacRes @maxVmor @ShelleyDolan2 @McArthurGrant #loilab @NBCFAus
So proud!! #VicForWomen #HonourHer @LoiSher Inducted to the Vic Honour Roll for Women 2022. Congratulations on your achievements ๐ ๐ฅ
Luis Lara @DrLuisLaraG is a postdoc in #LoiLab at @PeterMacRes, where he analyses (immuno)genomic data from clinical trials to identify tumour profiles with high risk of therapeutic failure to develop therapeutic strategies into future studies in #breastcancerresearch
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