Top Tweets for #OPSCC
Join us on Monday, June 1st for a KOL event to discuss updated data from the Phase 1/2 clinical study of CRB-701 featuring insights from leading #HNSCC experts: @AriRosenbergMD, @HeadNeckMD and @CesarAPerezMD
Register here: https://t.co/QNmWnMHynU
#ASCO26 #OPSCC $CRBP
Thank you @bradloncar of @BiotechTV for speaking with @CEOCorbus about our updated CRB-701 Ph. 1/2 clinical data being presented at #ASCO26 which demonstrated robust activity in 2L oropharyngeal & #cervicalcancers. Watch the interview: https://t.co/nSObkbhNcI $CRBP #HNSCC #OPSCC
๐๐จ๐ฆ๐ฉ๐๐ง๐ฒ ๐๐๐ฐ๐ฌ: Ahead of ASCO, @CorbusPharma is providing updated data today on its Nectin-4 ADC in cervical and head and neck cancer - @CEOCorbus describes how response rate appears to be directly related to HPV status. $CRBP
Full video: https://t.co/8JnpGk7JYC
#ESMOASIA25
Thanks to @myESMO Dr Oosting for supporting #HeadNeckCancer in the programme
Always fun to partner with Prof Brigette Ma to moderate #Deescalation of treatments in #HPV #OPSCC

๐ Role of Transoral Robotic Surgery in the Salvage Setting: Pitfalls and Challenges
โ๏ธ Madelyn N. Stevens & Alexandra E. Kejner
As #OPSCC incidence and survival increase, recurrence management is becoming critical.
๐ Read more:
https://t.co/jTVtYhrKe5
#TORS #HeadAndNeckCancer

Free download from @HeadNeckPathol โ @Pathologists updated #HPV testing recommendations! Just out! https://t.co/pcGh4MfKwR #ENTPath #OPSCC
๐ฃMust-read๐ฃfor any #pathologists who practice or have #ENTPath as part of their practice -- DOWNLOAD for FREE -- #CAPHPV testing guidelines #HeadNeckPath @HeadNeckPathol https://t.co/pcGh4MfKwR @MGBpathology @bfaquin #HPV #Oropharynx #Cancer

๐ข Phase III RCT in locally advanced #OPSCC: proton ๐ vs conventional #radiotherapy ๐
โ No diff. in 12-mo gastrostomy rate, QOL, or swallowing.
โ๏ธ Similar 2-yr local control & OS (~95%).
๐ High-quality IMRT remains standard; IMPT not required.
#ASTRO25 #RadOnc @ASTRO_org

๐ข New study on #OPSCC ๐ง introduces a probabilistic model to personalize elective nodal irradiation ๐ฏ
๐ Based on 833 patients + MCMC modeling
๐ง Hidden Markov model extended to bilateral lymphatic spread
๐ Factors: T-stage, midline extension, ipsilateral LN involvement
Key findings:
โ
Midline extension = strongest risk for contralateral spread
๐ Contralateral LNL III rarely involved if LNL II is negative
๐ LNL IV involvement nearly nonexistent without LNL III
๐ก Implication: For lateralized tumors not crossing midline, contralateral neck may be spared from irradiation โก๏ธ Less toxicity, same control ๐ฏ
https://t.co/nmoU1tOOMk

Recently published:
A proteomic signature for #HPV-associated oropharyngeal squamous cell carcinoma predicts patients at high risk of recurrence, by Christopher C. Jackson, @JiaJennyLiu, et al. https://t.co/qew3DYhUL7
@CMRI_AUS @kinghorncancer #OPSCC #proteomics #openaccess

Weโve issued new guidelines on the use of transoral robotic surgery in the treatment of oropharyngeal #SquamousCellCarcinoma: https://t.co/zGv1kh8vdS
Co-authored by @hnsurgeon, @patelMDDDS, @hstarmer, @DRNabilSaba, @vinpaleri #OPSCC #hncsm #oralcancer

HOOKIPA Pharma's Ground-breaking Phase 2/3 Trial Design for Combined HB-200 and Pembrolizumab Therapy: Unfolding Immunotherapeutic Revolution: $HOOK HOOKIPA Pharma Inc, a leader in the development of aโฆ https://t.co/aqadDXr3sb #opscc #HeadandNeckCancer #Hookipa #ClinicalStudy
HOOKIPA announces pivotal Phase 2/3 trial design for HB-200; potential for accelerated approval submission following Phase 2 primary analysis based on ORR; Investor call today; ASCO presentation with ~40 patients #headandneckcancer #OPSCC $HOOK https://t.co/BhifzoXFUU

A study from @YaleRadiology et al begins to explain the impact of 18F-FDG PET intensity normalization on radiomic markers of oropharyngeal squamous cell carcinoma #OPSCC and machine learningโgenerated radiomic biomarkers, potentially expediting the translation of exploratory radiomic tools into clinical applications.
https://t.co/BgF1CRsu0e
@SamPayabvash @Amit_Neurorad @MoritzGross5 @SmilowCancer @Yaleneuroradio1 @yalepathology @YaleMed @YNHH @JournalofNucMed
The Virtual Tumor Board, an AI-based tool to get the best treatment for #OPSCC patients, outperforms human MTB. @LabFuller rocking the stage #ICHNO2024 .
#vincentgregoire is not impressed ๐

Optimal PET Intensity Normalization Strategy for Radiomic Features of Oropharyngeal Squamous Cell Carcinomas #OPSCC for Machine LearningโGenerated Biomarkers @Amit_Neurorad @MariamAboian @BenjaminKannMD @YaleRadiology | https://t.co/ZbFbn0CcKs
New ๐ฐ from @MSKCancerCenter @MskMedPhys on the implementation & accuracy evaluation of the auto-segmentation algorithm, โMasked Image modeling using the vision Transformers (SMIT),โ for neck nodal metastases on MR images in #OPSCC #HNCSM pts.
๐https://t.co/WHXh6xrhC6

Medical oncologic approach to #OPSCC @khonkaenunivers Head & Neck Oncology 2024. Making @MGHCancerCenter @MassGeneralMDs @MGHMedicine proud! Thank you, Khon Kaen University!

HPV+ #OPSCC have increased at alarming rates in the US. Itโs an honor and privilege to be multi-PI of this exciting project working with @AnnaGiuliano19 and her @MoffittNews team! Thank you @NIDCR leadership for assembling this AHEAD initiative to support early detection research
Moffitt Cancer Center has received a $3.6 million grant to evaluate a screening test for oropharyngeal cancers. The research, led by Dr. Anna R. Giuliano (@AnnaGiuliano19) addresses key challenges posed by late-stage diagnoses.
Read more: https://t.co/Rb0cHUohcb
#CancerResearch

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