Top Tweets for #PLA2R
The #PLA2R Paradox: Seropositive #Membranous #Nephropathy With Negative Staining
#KIRNephrologyRounds
https://t.co/tUfEttXXt0

#nephrotopo
💥Traitement de la #GEM basé sur le risque :
🟢Faible risque → surveillance seule
🟡Risque modéré → CNI ± rituximab
🟠Haut risque → IS d’emblée
🔴 Très haut risque (IRA, PLA2R+++…) → CYC recommandé
🎯 Adapter le traitement au profil évolutif !
#GEM #PLA2R

#nephrotopo
La rémission spontanée dans la #GEM n’est pas rare, même avec une protéinurie élevée
📉 >4 g/j → 45 %
📉 >8 g/j → 34 %
📉 Prot. petit PM élevée → 25-30 %
🧪 Anti-PLA2R ↑ → 17-20 %
📌 D’où l’approche individualisée #KDIGO 2021
#Néphrologie #PLA2R #Proteinurie

Hoy se presentó la cohorte de Nefropatía Membranosa APLA2R del @NefroINCMNSZ!
Gran equipo con @Ben_gar_glz y @quinonezmd
#IMIN2024 #GlomLover #PLA2R
@IMINmx @Meyaix

Phase 1b/2a Study Assessing the Safety and Efficacy of F#elzartamab in Anti–Phospholipase A2 Receptor #PLA2R Autoantibody-Positive Primary #MembranousNephropathy
#VisualAbstract by @drpriyajohn
https://t.co/ehrO5oONtF
@BradRovin

Unveiling the mystery 🕵️♂️🔍: Exploring unique clinicopathological features and treatment outcomes of PLA2R-related idiopathic membranous nephropathy in enigmatic case of seronegative PLA2R antibodies. #Nephrology #PLA2R #MedicalResearch
https://t.co/981TB7Plv5
#PLA2R antibody does not outperform conventional clinical markers in predicting outcomes in #Membranous Nephropathy
#VisualAbstract by @edgarvlermamd
https://t.co/JiOpzZtAAn

Interesting approach of Antibody-Guided Therapy in #PLA2R -Associated #Membranous Nephropathy using #cyclophosphamide. https://t.co/zEp3DP5Xzo #NephTwitter
R: #NefropatiaMembranosa EII
Enf. x Complejos inmunes depositadis en espacio subepitelial (SE). La NM se menciona como la enfermedad de los 3, por qué?
1⃣/3⃣ Remisión
1⃣/3⃣ Estables
1⃣/3⃣ Pérdida progresiva #Fr
El #Pla2r es ag en alrededor del 70% de las NM primaria.
1/3

The March issue of @Kidney_Int features studies and commentaries related to #membranous #nephropathy, reporting 17 new putative #antigens and the first #epitopes recognized by T-cells, thus opening exciting perspectives for targeted therapy.
#PLA2R
https://t.co/L0XPiZ7XTE

Case report of #PLAT2R Ab positive #MN 2/2 infection. Take home message —-> causes with anti #PLA2R abs can also have associated malignancy and #infection @GlomCon

Antibody guided therapy in #PLA2R-associated #membranous nephropathy
#VisualAbstract by @krishnadoctor1
https://t.co/lSjzyIpKva

Prueba serológica para #PLA2r 👇🏼
@IMINmx
@AvelRomanNeph
#IMIN2022 #MN #NM #membranousnephropaty #NefroptiaMembranosa
Clinicopathological Characteristics and Outcomes of PLA2R-Associated Membranous Nephropathy in Seropositive Patients Without PLA2R Staining on Kidney Biopsy
https://t.co/P8rg57GbqH
#PLA2r #kidneybiopsy

#EQA #samples for week 43 are on their way #CSFB2T #GAS #PLA2R #CRYO #TeamUKNEQAS #HealthcareScience
A sample from the pathology teaching slide set on Membranous Nephropathy, jointly prepared by Arkana Laboratories and @goKDIGO: https://t.co/NJrQWKYKw1
#PathTwitter #renalpath #PLA2R #NELL1

Sero+ #PLA2R MN without PLA2R staining on #kidney #biopsy -distinct clinical subtype with more severe dz, worse prognosis & poor response to Rx. Any similar experience? #NephTwitter @RajguptaEM @GlassockJ @ClarissaCassol @Tiff_Caza @arkanalabs https://t.co/2nfnUzdEhn
#KDIGO GN guidelines 2021. #kidney #biopsy not required to confirm diagnosis of #membranous #nephropathy in #nephrotic syndrome and + anti #PLA2R ab. Assuming normal renal fn and no DM, Would you go ahead & Rx or do a biopsy first & decide? Thoughts? #nephtwitter #askrenal

#Lectin complement pathway activation in anti #PLA2R membranous nephropathy
#complement as a disease mediator and treatment target in #MN

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