Top Tweets for #PSCK9
Oral #PSCK9 inhibitors such as #enlicitide decanoate may offer a significant future avenue in lipid-lowering treatments for #ASCVD. Professor François Mach discusses the evidence and outlook for this new class of drug in his presentation to @PCSK9Forum >> https://t.co/e1C0o8y9A0

$SGMO Sangamo zinc finger #epigenetic
Chroma Medicine, co-founded by #Lombardo and Harvard researcher #David #Liu, to explore epigenetic editing in human trials
Unlike traditional DNA modification, #epigenetic editing offers the advantage of #reversibility...
#PSCK9
An alternative to genome editing can reduce the activity of a gene that affects cholesterol levels without changing the DNA sequence https://t.co/wANkyun4rD
#Lerodalcibep a small recombinant fusion protein aganist #psck9 showed similar effects with w/ evalocumab #EASCongress2023 @society_eas @society_eas @ProfKausikRay patients from Turkey And India

Join the #HyperLipidemia experts Peter H. Jones, MD, MNLA, & @ScottWrightMD for a Live MasterClass and Practicum on #PSCK9-targeting therapies at #AHA2022! 11/7 at 6:30 AM CST (also available online at 7:30 AM EDT) https://t.co/Om9Zm2hzZc @American_Heart #Cholesterol #MedEd

➡El Dr. Xavier Pintó del Servei de #MedicinaInterna de l'#hbellvitge ha participat en el Congrés de la Societat Europea d’Aterosclerosis i ens informa sobre les noves perspectives presentades en relació a la #PSCK9
🎥 https://t.co/XeW4JYHCZg
#HighlightsEAS2022
#hospitalenxarxa

Hoy, en #HighlightsEAS2022, el Dr. Xavier Pintó del @hbellvitge nos da su opinión sobre las novedades presentadas respecto a la #PSCK9.
¿Abrimos debate?
👉Accede al vídeo: https://t.co/uKR23hQhTp

3a Sesión Estatutaria-Actualización en todos los temas de Cardiología 🫀 @smexcardiologia #EstatutariaSMC @SIAC_cardio.

Heart patients need proper access to medication, but only 1 in 3 patients have access to #PSCK9 inhibitors under the affordable #PartD preferred brand-tier. We ask @CMSGov to ensure our patients have access to affordable innovative therapies. #MendedHearts https://t.co/vUrtZGwoJg
And the full version is available here! 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol #AHA2018 #guidelines #statins #PSCK9 https://t.co/CqQ9bnSnCO
O terapii inhibitorami PCSK9 - kosztowo-efektywnym rozwiązaniu dla systemu, które wciąż nie doczekało się refundacji.
#psck9 #inhibitorPCSK9 #nowoczesneleczenie #hipercholesterolemiarodzinna

O terapii inhibitorami PCSK9
https://t.co/0af2a6EZUC
@PiotrJankowski_
#psck9 #inhibitorPCSK9 #nowoczesneleczenie #hipercholesterolemiarodzinna
O terapii inhibitorami PCSK9 - kosztowo-efektywnym rozwiązaniu dla systemu, które wciąż nie doczekało się refundacji.
#psck9 #inhibitorPCSK9 #nowoczesneleczenie #hipercholesterolemiarodzinna

O terapii inhibitorami PCSK9 - kosztowo-efektywnym rozwiązaniu dla systemu, które wciąż nie doczekało się refundacji - w dzisiejszej @rzeczpospolita
https://t.co/1odqJsO1f6
#psck9 #inhibitorPCSK9 #nowoczesneleczenie #hipercholesterolemiarodzinna
#SaCas9を用いた #アデノ随伴ウイルスベクター によりマウスの肝臓のコレステロールを制御する遺伝子
#Psck9 を標的に #ゲノム編集 を行った例
Ran, F.A. et al. (2015) In vivo. genome editing using Staphylococcus aureus Cas9. : Nature.(2015) ;520(7546),186-191.
https://t.co/9jXNhs28EX https://t.co/eIymhTZg3N
#AMED #成育疾患克服等総合事業
山形崇倫先生ら
#難治性小児神経疾病である #AADC欠損症 患者2名に #アデノ随伴ウィルス( #AAV )ベクターを用いた遺伝子治療を実施。治療後、遺伝子治療の #副作用なし 治療後2か月で全身が強直する #ジストニア 発作が消え、運動機能が改善
https://t.co/Jtl04h3c8r https://t.co/dIpnEERKb2
"The system is really broken." ASPC President, Dr. Seth Baum, discusses how every #RX he wrote for a #PSCK9 inhibitor was denied. https://t.co/265PXEGqoQ via: @advcardiohealth @TheFHFoundation @drlipid @DrMarthaGulati @patientaccess #knowfh
Another way to look at it. Amgen & Regeneron/Sanofi called the wrong play by misreading the defense. They thought #PSCK9 drugs were a new category. Insurers and PBMs saw just really pricey cholesterol-lowerers.
Amgen & Regeneron/Sanofi are like the landlords who wouldn’t lower the rent on their vacant storefronts, stubbornly waiting for the market to wise up. If #PSCK9 drug prices were ⬇️ to start, companies would have made more 💰and avoided this mess. https://t.co/TGqtfAhpbv
Big news: $regn/$sny’s Praluent cut deaths in a big study. The companies are offering bigger discounts. Can patients finally get these drugs? https://t.co/cFwj548hWv
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