Top Tweets for #PanCancer
Researchers developed PROGPATH - a unified, weakly supervised #DeepLearning model for #Pancancer outcome prediction, significantly improving prognostic accuracy and risk stratification across diverse #Cancer types.
#STTT #OpenAccess: https://t.co/WYG2kBg6vj
@CFerroneMD of @MassGeneral leads Alliance A021806 studying whether chemotherapy before and after surgery is better than just after surgery for pancreas cancer. Learn more: https://t.co/juUQ8BcFu8 #NCI #NCTN #pcam #PanCancer #PancSM #PancreaticCancerAwarenessMonth
"...the convergence of high-resolution #multiomics with sophisticated #AI is poised to redefine #premalignant lesion research, enabling #pancancer exceedingly-#early risk stratification and pharmacological #prevention."
For example, #multiomics analysis of #colorectal #polyps from #patients w/ #familialadenomatouspolyposis/#FAP found that the #arachidonicacid pathway was up-regulated early in hyperplasia, which was targeted by #aspirin, giving a potential explanation of the preventative #treatment mechanism. @EdEsplin et al. https://t.co/hAEJsMOr4A @NatureCancer
#genetics #genomics #RNASeq #proteomics #metabolomics #lipidomics #CRC #colorectalcancer #precisionmedicine #precisiontherapy #clinicaltrials #precisionprevention @CGAIGC
https://t.co/hxjR7vX83T #FeiranZhang et al. #Research @ScienceMagazine
Proud to introduce TIME_ACT: an unsupervised, #pancancer signature, which accurately identifies hot tumors and predicts response to #ICB across #Cancer from tumor transcriptomics and histopathology. 🧵 (1/6)
📄 https://t.co/Vrn3NimCSy
"Implementation of #pancancer #universal #germlinetesting in an ethnically diverse and rural #community #oncology practice." (NCT05416710)
Prospective #patient cohort, 30% AA, 27% w/ annual income < $25,000, w/ #breast, #colorectal, #lung, #headneck, #prostatecancer, among others, received insurance-billed, #universal #genetictesting, nearly 1:10 #patients w/ PGV, >50% would be missed by @NCCN
Making
https://t.co/wa8YmWUWs3 @JCO_ASCO @VivekSubbiah @Dr_R_Kurzrock
&
https://t.co/tFSemI4b2i @JCOPO_ASCO
a reality in the community...
https://t.co/V2aoUgUnWJ #ASCO25 @ASCO
#access #reducedisparities #precisionmedicine #precisiontherapy #clinicaltrials #precisionprevention
📢Check out this Research Article by Jens Kleesiek, Martin Schuler, Frederick Klauschen and colleagues @NatureCancer
'Decoding #pancancer treatment outcomes using #multimodal real-world data and explainable #artificialintelligence'
🔗https://t.co/bwtoRiwrXV
New #pancancer study reveals #age-associated genetic alterations in protein domains. Uncovering age-stratified #hotspots & their role in cancer #pathways could revolutionize precision diagnostics & treatments. #CancerResearch #Genomics #PrecisionMedicine
https://t.co/6cieUsKd94
(5/5)
📄 Read the full paper: https://t.co/Cj48Ij48T6
🖥️ Explore our Shiny app to analyze protein expression across cancers!
https://t.co/SdoM0p8iqq
#CancerResearch #Proteomics #PanCancer #FFPE #Bioinformatics
We extend these findings to the #PanCancer level using the large-scale #TCGA and MET500 cohorts, demonstrating higher similarity in metastases to their target tissues when compared to primary samples, which remain more akin to their origin tissues. 🧵6/10
Are metastatic #cancers more like their normal origin or target tissues? Our work in @ScienceAdvances systematically compares the #transcriptomics of primary and metastatic #tumors to healthy tissues in a #PanCancer, genome-wide manner! #metastasis 🧵1/10 https://t.co/DWdkyMOXsv
Recently published:
SpliceMutr enables pan-cancer analysis of splicing-derived #neoantigen burden in tumors, by Theron Palmer et al.
https://t.co/oLC1lnV42W
@NeehaZaidi @ValsamoA @KarchinRachel @FertigLab @JHUBME @hopkinskimmel @ConvergenceInst @UMGCCC #pancancer #openaccess
This week, we talked about how #Pancancer #Proteogenomics with @theNCI #CPTAC informs #PrecisionMedicine @BCMCancerCenter symposium. Results of these studies are freely available at https://t.co/OraxEzWjkR. Together we will advance #PrecisionMedicine!
New bulk rnaseq #pediatric pan #cancer data set available in https://t.co/ZrQJ6Hh2gE
R2 open online data science platform for biologists and biomedical researchers.
2680 citations in PubMed
#paediatric #pancancer
#Pancancer✅#Proteogenomics✅#Precsiononcology✅Our public resource for protein and peptide cancer targets is out! It's crazy to think I could barely code and understand statistics when I started this job. All authors in this study have been my mentors.
https://t.co/ScEUEsZAjX
Great meeting! #PanCancer & robust discussion. Tackles issues other meetings don't! Sorry to be missing it this year, but #WhereisHoskin will be there! Enjoy the #bladdercancer session - it's going to be feisty! 👇🏽👀
Great discussion about the need for rigorous clinical validation for new AI tools - @DrMiaLevy
@FoundationATCG
@VivekSubbiah @anantm @AACR
https://t.co/xOpxQxRXus
#oncodaily #oncology #cancer #AACR24 #AIinOncology #clinicalvalidation #AI #pancancer #cancerresearch
Pan-cancer comparative and integrative analyses of driver alterations using Japanese and international genomic databases
High #TP53 mutation rate in Asian patients across cancer types #pancancer #precisiononcology https://t.co/qywZcpbbjz
New resource report in the January 15th issue—
Integration of #PanCancer #SingleCell and Spatial Transcriptomics Reveals Stromal Cell Features and Therapeutic Targets in Tumor Microenvironment, by Yanhua Du et al.
https://t.co/7zpor7oLk7
Last week at ZAODX’s World Conference on Early Detection of Cancer, Prof. Moshe Szyf presented on #DNAmethylation's role in #cancerprediction, #prevention & intervention. He also discussed HKG's groundbreaking epigenetic tests for #cervicalcancer, #livercancer & #pancancer.
We extend these findings using the #TCGA and MET500 large-scale #PanCancer cohorts, demonstrating higher similarity in metastases to their target tissues when compared to primary samples, which remain more akin to their origin tissues. (5/9)
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