Top Tweets for #PathHarrySpotter
Merckel cell #pathharryspotter
85y/o F with 4cm fast growing mass on the left thigh... #Pathology #pathtwitter #dermpath #bstpath #pathboards @EinsteinPath @EinsteinMed @yokoda_md @JMGardnerMD @anjuthevirgo @RFecherMD

- Malakoplakia (von Hansemann cells) in an older woman presenting as a bladder mass
- Eosinophilic cytoplasm and round nuclei
- Distinct, targetoid intracytoplasmic inclusions (Michaelis-Guttman bodies) are prominent in this case
- Von Kossa stain confirms that #GUpath

Autoimmune lymphoproliferative syndrome (ALPS)
▶Follicular hyperplasia ± PTGC ± regressed follicles
▶Prominent paracortical hyperplasia by polyclonal αβ T-cells: CD3+CD4-CD8-CD45RA+CD45RO- with high proliferation and CD57+, TIA+, perforin+
▶Polyclonal plasmacytosis

A perfect Lymphoepithelioma-like hepatocellular carcinoma (LEL-HCC).
Rare variant
Overall lower recurrence, overall favorable survival rate
Not associated with EBV
High level of PD-L1 and PD1 in intratumoral inflammatory cells
https://t.co/iYr1hfFYOa
#liverpath #pathtwitter

Solid pseudopapillary epithelial neoplasm (SPEN) of pancreas...
#pathharryspotter
https://t.co/DScMQ1k2JA
Young F with abdominal pain.
CT showed a mass in pancreatic tail.
What’s your diagnosis?

Here's a traditional didactic video on IgG4 related sialadenitis. I've never been able to tolerate an hour long lecture! I'd love to see a CME that would twitter size their lectures! #ENTpath

Pulmonary Corpora Amylacea , a rare entity, characterized with homogenous laminated structures, BAL, Cytopathology #179 #CytoPro @PathPro @barkanga @IvanaKholova @mtsiddi @eva_wojcik @mdlozanoe @PVielh @MauroSaieg @britishcytology @twmarkc @aakasharmand

METAPLASTIC BREAST CARCINOMA
Invasive breast carcinoma with mesenchymal differentiation
IH: AE1/AE3, SMA and p63
#path #surgpath #pathclues #breast #breastcancer #breastpathology

Leiomyoma #pathharryspotter
Polyp removed from the TC. H&E histology attached
WHAT IS THE DIAGNOSIS?
a) serrated polyp
b) adenomatous polyp
c) leiomyoma
d) NET
e) small CRC
As usual, I'll upload an explanation onto https://t.co/7fdeMHpKRq in the middle of the afternoon.

Sessile serrated adenoma/ Polyp #pathharryspotter
Sessile serrated adenoma/polyp. Ascending colon, ESD. HE stain.

Polyp from mucosal prolapse #pathharryspotter
This lesion was found in the rectum of a patient undergoing colonoscopy because of constipation
WHAT IS THE LIKELY DIAGNOSIS?
a) polyp from mucosal prolapse
b) serrated polyp
c) adenomatous polyp
d) malignant polyp
As usual an explanation on https://t.co/n0x9Fe6F0z this afternoon

Sessile serrated lesion within IBD #pathharryspotter
SPIROCHETOSIS
#pathharryspotter
Cute intestinal spirochetosis.

Collagenous spherulosis
#pathharryspotter
Collagenous spherulosis of the breast - often incidental finding
Spherules stain light pink to pale blue, most have darker PAS-positive peripheral rim
Composed of collagen type IV & laminin
Surrounded by benign myoepithelial cells - SMA, S100 & CD10 +ve
#BreastPath
1/3

Myrmecia
#pathharryspotter
Young female with foot lesion
~Plantar wart (Myrmecia)🔬
~Prominent intracytoplasmic pink/purple inclusions & granules of varying sizes & shapes
~Caused by HPV1
DDx: Mollscum Contagiosum
~Myrmecia= 🐜 (clinically resemble anthill)
#dermpath #Pathology #pathresidents #dermatology

Pinguecula
#pathharryspotter
Dermatitis Herpetiformis
#pathharryspotter
Dermatitis herpetiformis: itchy bumps; microabcesses in dermal papillae + gran IgA deposits on DIF #dermpath #pathology #dermatology

Micropapillary urothelial carcinoma
#pathharryspotter

Chordoid meningioma
#pathharryspotter
50yr F with a 2cm clival tumor: chordoid meningioma, #WHO grade II. #brain #pathtwitter #neuropath @EinsteinPath @RFecherMD @RawVeganDoctor @DrGeeONE @VHNguyenMD @NYPathSociety @yokoda_md @anjuthevirgo @CraigHorbinski @slusagar

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