Top Tweets for #PhIPseq
Our #MouseScan™ #PhIPSeq is designed to analyze preclinical murine samples for autoantibodies against the full GRCm38.p5 mouse proteome in a single-well assay with quantitative sequencing readouts. It provides simultaneous epitope-level autoantibody profiling across the entire murine proteome using Phage ImmunoPrecipitation Sequencing (PhIP-Seq). With content exceeding 50,000 proteins and isoforms, and covering over 480,000 unique peptide sequences, MouseScan delivers precise, quantitative insights. Available to both academic and industry scientists, this cutting-edge technique offers high-resolution data for a diverse range of research.
Learn more here,
https://t.co/hvvr2tIhtA
#proteomics #proteome #phipseq #sequencing #antibodies #autoantibodies #seromics #biotech #lifesciences
PRESS RELEASE: We are thrilled to announce our exclusive Technology Access Program, designed to empower your research with epitope-level antibody discovery and profiling using a customized #PhIPSeq library. With this program, you can tailor the library to align with your research focus, whether it be a specific disease, autoimmune disorder, allergy panel, or any other application. Furthermore, you can seamlessly integrate new content into any of our existing PhIP-Seq panel products. Our innovative spike-in approach allows for expanded panel content, providing a cost-effective and customized solution tailored to your unique research requirements.
Learn more here,
https://t.co/9ADjUUVyty
Read press release here,
https://t.co/XMgYHu1a7F
#autoimmune #proteomics #seromics #antibodies #autoantibodies #biotech #lifesciences
ARTICLE: In a featured article published in Rheumatology, Po-Ku Chen and his team at China Medical University Hospital leveraged CDI Labs' multiplexed #PhIPSeq platform to discover peptide biomarkers that predict positive therapeutic response to tofacitinib in rheumatoid arthritis (RA) patients. Their research identified two key peptide antibodies, anti-SNRK and anti-HUWE1, as effective pretreatment predictors of favorable outcomes with tofacitinib therapy in RA patients.
View article here:
https://t.co/euHZBauNjh
#arthritis #biomarkers #tofacitnib #antibodies #proteomics #biotech
Researchers from UCSF and @czbiohub have discovered a harbinger in the blood that can predict #multiplesclerosis (MS) five years before symptoms appear. The breakthrough could lead to earlier diagnosis and more effective treatment. https://t.co/IvVK50Zjv4
.@drannalieb @larmanlab @BenLangmead develop Dolphyn for compressing large proteomic spaces and discover human antibodies targeting gut bacteria-infecting phages. #Dolphyn #PhIPSeq #BiotechNatureComms
https://t.co/MdL1fhNM9e
And here is the thread by @BourgonjeArno on our second @ImmunityCP paper https://t.co/DA1qKlxe8l on #PhIPSeq in #IBD findings:
Very happy to announce that today two papers on #PhIPSeq in (1) the general population (🧵 by @sea_andreu) and (2) in patients with inflammatory bowel diseases (#IBD), got published today in @ImmunityCP https://t.co/N1VhJNijEJ
https://t.co/8wCMV3YeEp 🧵 on IBD findings:
Very happy to announce that today two papers on #PhIPSeq in (1) the general population (🧵 by @sea_andreu) and (2) in patients with inflammatory bowel diseases (#IBD), got published today in @ImmunityCP https://t.co/N1VhJNijEJ
https://t.co/8wCMV3YeEp 🧵 on IBD findings:
Patients with IBD showed particular IgG-coating of #Streptococcus, #Lactococcus and #Lactobacillus , but also overlap in responses with controls. Further study into the exact antigenic nature of these antibody reactivities is needed (e.g. using #PhIPSeq: https://t.co/VSqeyLnGLL)
More #PhIPSeq at @researchumcg.
#IBD patients show a distinctive antibody pattern where CD patients are characterized by the widespread presence of antibodies against bacterial flagellins.
Now out in @biorxivpreprint
And another preprint online! In this study we characterized the antibody epitope repertoire in patients with inflammatory bowel diseases (IBD) leveraging #PhIPSeq technology which enabled to study antibody responses against >300,000 peptides
https://t.co/kBtDr5P3vV
And another preprint online! In this study we characterized the antibody epitope repertoire in patients with inflammatory bowel diseases (IBD) leveraging #PhIPSeq technology which enabled to study antibody responses against >300,000 peptides
https://t.co/kBtDr5P3vV
Happy to give our work a plug once again.
In our latest preprint we use #PhiPSeq to characterize the antibody repertoire of ~1,400 Dutch @LifelinesNL participants against 300,000 peptides belonging to microbial and environmental antigens.
https://t.co/IOYH9dkdUm
Amazing talk today at NIH Clinical Neuroscience Grand Rounds by Dr. Michael Wilson of @UCSFMedicine and the Center of Next-Gen Precision Diagnostics! #Metagenomics #PhIPSeq #Neuroinflammation #NeuroinfectiousDisease
Timothy O’Donnell @timodonnell uses #PhIPseq to identify responses against autoantigen after checkpoint blockade #immunotherapy. #Priism2018
Wow, this year brings Nobel Prizes for checkpoint blockade therapy (Physiology or Medicine) AND bacteriophage display (Chemistry)! Now if only there was a way to use phage display to study responses to checkpoint therapy... 🙄 #PhIPSeq! https://t.co/dRWH58B0Kd
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