Top Tweets for #PolygenicScore
Our large cohort study provides robust population-based evidence that #neonatal vitamin D status, as measured by #25(OH)D, #DBP, and their #polygenicpredictors, is not associated with #asthma risk.
See here 🔗 https://t.co/um3VCxmtgd
.
#asthmarisk #cohortstudy #polygenicscore #populationbased #registers #vitamin D #PAI_journal #originalarticle #openaccess
I'm very excited to present our recent work, led by Xiaohe (Lucy) Tian @xiaohetian89, at the upcoming online symposium on #PolygenicScore.
"PRISM: systematic #ancestry- and #tissue-specific #integration of genomic #annotations enhances the #transferability of polygenic scores"
I am excited to present our recent and ongoing efforts on #PolygenicScore modeling at @UCLA’s #Frontiers in #Bioinformatics seminar today at noon!
Don't miss William Li's presentation 1050W this afternoon at the @GeneticsSociety, American Society of Human Genetics.
Learn more about our presentations:
https://t.co/WbQDZuytFO
#polygenicscore #biobanks #alzheimers #subtypes #heterogeneity #ASHG #ASHG25
I'm very excited to present at #ASHG #ASHG25 in Boston!
I had the luxury of working with fantastic students and am proud to see their upcoming presentations.
The Tanigawa Lab at @UCLA @BioEngUCLA is also recruiting (more in 🧵)
Why is this important? There's a trend to label between-family effects as "spurious" or "biased." We argue they are a valid part of prediction for the whole population and shouldn't be dismissed. It's not bias, it's just... reality. #genetics #education #cognitive #polygenicscore
Long awaited peer review finally completed!! Our paper comparing quantitative metabolomics disease risk prediction with PGS is accepted in Nature Comms!! 🥳🥳
https://t.co/vUI28vodSX
@NgaleHealth #riskprediction #metabolomics #nmr #genomics #polygenicscore
Excited to share our #GenoBoost paper out in @NatureComms today, a flexible #PolygenicScore #PGS modelling framework for additive and #NonAdditive dominance effects, incorporating non-zero dominance effects in 40%-67% of variants across multiple traits, including #psoriasis, #RheumatoidArthritis, #gout, #IBD, #Alzheimers and more, with @YK_Tani #YosukeTanigawa at @MIT_CSAIL, and #RikifumiOhta and #ShinichiMorishita at @utokyo_gsfs_en.
Paper: https://t.co/MiIXtoNkYH
News: https://t.co/o0iQ1Mnn2g
Don't miss #YosukeTanigawa @yk_tani poster PB_4327 at #ASHG23 #ASHG on The Power of #Inclusion in #PolygenicScore calculations #PGS or #PolygenicRiskScore #PRS, in the #StatisticalGenetics and #GeneticEpidemiology section.
Key result: Diverse ancestry inclusion improves prediction accuracy for all genetic backgrounds, especially AfricanAncestry up to 60% improvement on average with iPGS and iPGS+Refit methods.
Building on Yosuke @yk_tani's paper just published in @AJHGNews last week! Poster session is now!
Abstract: https://t.co/9u9IUyxIw2
Excited to share our Inclusive Polygenic Score (iPGS) work and iPGS+refit, out at #AJHG today by @yk_tani.
We improve #polygenic prediction of #DiseaseRisk and other traits across individuals from #diverse populations/ancestries, that have been traditionally excluded from #genetic studies, using individual-level data for individuals across the #continuum of genetic ancestry.
Improvements of 60% on average for African-ancestry and 18% for admixed-background individuals, and discovery of population-specific genetic effects.
Paper: https://t.co/a0DvevIoZQ
MIT news: https://t.co/ZTEYDfDDbX
Tweetorial: https://t.co/6DI6vZazbX
AJHG tweet: https://t.co/6DsQWCQD52
CSAIL tweet: https://t.co/0O14Zbh80l
Browser: https://t.co/3ovXKnRAkd
#AortaGene����
#AORTAScore (clinical covariates)+aortic #PolygenicScore
Explaining 35%~42% variance in #AscendingAorticDiameter
Identify👤ɸ≥4cm in 4 cohorts
UK Biobank
MGB
FHS
All of Us
#AortaEd
@jpirruccello @MarkELindsay @patrick_ellinor bioRxiv 2023
https://t.co/qZBusrDiqF
A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease | Nature Medicine
https://t.co/k8QhiO69pn
#PolygenicScore
BioDecoded Daily Digest | May 19, 2023
https://t.co/nM5lp3vtKJ
#PolygenicScore #DeepLearning #MachineLearning
Polygenic scoring accuracy varies across the genetic ancestry continuum | Nature
https://t.co/357XYLMmeG
#PolygenicScore
🧠Association of #PolygenicScore and the involvement of Cholinergic and #GlutamatergicPathways with #LithiumTreatment Response in Patients with #BipolarDisorder, Feb 14, Amare A et al.
@UniofAdelaide @WWU_Muenster @DrFColom @IMIM_research @CIBER_SAM ...
https://t.co/zUSMBPdZrQ
Genetic nurture versus genetic transmission of risk for ADHD traits in the Norwegian Mother, Father and Child Cohort Study. By Jean-Baptiste Pingault et al. @ucl @KingsCollegeLon #ADHD #hyperactivity #attentiondeficit #polygenicscore #OpenAccess https://t.co/1ZKKmbas3N
Genetic Architecture+Ethnic diversity😎of #AscendingAortaDiameter
#UKBiobank
#MillionVeteransProgram
#FinnGen
#PennMedicineBiobank
#PolyGenicScore HR=1.42 -> #ThoracicAorticAneurysm
Dr. James Priest lab @NatureGenet 2022 @ines_catherine @JamesRPriestMD
https://t.co/f9Kp57LgfP
An electronic health record biobank study investigating the interaction of #obesity #polygenicscore with #lifestyle risk factors
Read it here:
https://t.co/qOGbAP0brl
(3/8) Before the age of 2, the #ADHD #polygenicscore was robustly associated with hyperactivity & inattention, with increasing strength up to 8 years, & with language difficulties at age 5 & 8.
@jarevez @NatureComms @WrayNaomi @John_J_McGrath Also released is our second #PolygenicScore for Non-alcoholic fatty liver disease (#NAFLD) from @CristianaBianco & @lucavalenti75 in @JHepatology. See it here 👉 https://t.co/1g5CMIxR8w
Browse the full list of traits with PGS/PRS in the @PGSCatalog 👉https://t.co/m7Fh1EcdK4
NEW DATA! Thanks @jarevez for submitting the #VitaminD SBayesR #PolygenicScore from @NatureComms w/ @WrayNaomi @John_J_McGrath! See it here 👉 https://t.co/ZFwAkPBFtS
If you want to share your data in the Catalog see https://t.co/pIDGyikNU7 (pre-publication embargoes accepted!)
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