Top Tweets for #PreSymptomatic
How dangerous epidemics spread:
either through people before they have symptoms #presymptomatic or in people who'll never develop symptoms #asymptomatic, simply because diseased people minimized contacts with non-infected people. #Ebola #HIV #Covid #virus
https://t.co/hEDOxRo4tJ
#Presymptomatic and #asymptomatic Covid transmission.
This is a very strong citation as cited by Klompas and Rhee.
59% of all transmission came pre/asymptomatic transmission,
35% presymptomatic individuals
24% asymptomatic.
Here:
https://t.co/wBpO0ebpiH
/1
PAPER ALERT‼️ Sara Costa-Pinto, from the team of
@SandraHVaz1 described the lack of supportive functions of #cortical #astrocytes in regulating #M1 #neuronal #transmission in a #presymptomatic #SOD1G93A #ALS mice
Check out the paper:
https://t.co/SQnQQq0Gj9
@IMMolecular
@FMUL
REACT-HD #huntingtonsdisease was born 'cause pp w #presymptomatic HD were put off attending support groups. Sitting in front of a person that reflects how you potentially will be in 20years can be so scary. People w #parkinsonsdisease also report avoiding groups for this reason
REACT-HD online group: supporting people living with pre-symptomatic #huntingtonsdisease https://t.co/naDZoTu1Xy
I am so pleased to see this work published developed @UHSFT @UHSFTresearch @ochiefbanana C Kipps. Work done during #Covid_19 #mayawarenessmonth #hdresearch #userdriven
Recent advances in #SMA therapy and the detection of #presymptomatic patients requires a multi-disciplinary approach for communicating results #geneticcounseling #psychologicalimpact https://t.co/mfT2j79gtw #GIMOpen.
Where: #IDS2023 Poster Session III
When: Tomorrow May 26 18:30-19:45 CEST Section
What: Dr. Jason Tsai presents improving early #diagnosis of #presymptomatic stage 2 #T1D with a sample-sparing assay
Follow more coverage: https://t.co/zEAqJisy16
#HOTposter
☣️ Study finds evidence of ‘considerable’ #presymptomatic spread of monkeypox
🔔 #Monkeypox
https://t.co/StnLbsJu6V
Exciting announcement from the NIVD Team! #NivdWorld #EarlyDiagnostics #PreSymptomatic #Nano #NanoTech #NanoSensors
#PCBCommunity | @NIVDWorld, a #deeptech startup focused in vitro #nanodiagnostics, opens in #PCB_UB ▶️ https://t.co/wUwcchNHB3
Welcome on board @TriguerosS & team! 👍🤗
@oxmartinschool @GeneticsUB @BiologiaUB @In2Ub #nanosensors #nanomedicine #earlydiagnostics #oncology
@Kelly_Quinlan I will provide @GTMBB a free @ViralSign station for 30 days. @GTJoshPastner need only to reach out. Tech needs the advanced screening science in Viral Sign to detect #infectiousdisease during #presymptomatic phase when viral shedding is most aggressive.
@KarinEklund7 Topplocket gick igår när jag fick veta hur många som var sjuka i covid på ett av mina barns skolor utan att vi ens fått veta något. Jag kontaktade rektorn ang åtgärder, då vi ej hört ngt och med tanke på hur viruset sprids. #COVIDisAirborne #presymptomatic Detta svar fick jag.
Super excited to be showcasing our #huntingtonsdisease online support group project #ReactHD with @ochiefbanana @UHSFT @HuntingtonSG #UNMASKINGHD. Come visit our booth at "Basic science & general topics" and discuss the unaddressed needs of people in the #presymptomatic stage
The 28th Annual Meeting has officially begun!
Don’t miss any of #HSG2021: #UNMASKINGHD!
Register Here:
https://t.co/tE9s6gORUF
Agenda & Sponsors List:
https://t.co/yQ89MR3LWK
@DFisman @AshTuite @PNASNews @Alison_Galvani Taught my #teachered students about #presymptomatic & #asymptomatic #COVID19 cases today & infectious windows from pre-Delta & #Delta data. As well as #R0 what it means & how #Delta different vs previous strains in reproductive rates
@patience_not @CDCMMWR Though keep in mind, infected shed greatest amount of #COVID19 virus—generally before symptoms—so what was she doing when #presymptomatic? Some never symptomatic. Also infected #vaccinated been found to have similar viral loads to #unvaxxed—& can transmit.
Delta’s rise is fuelled by rampant spread from people who feel fine. estimated #Delta has R0 of 6.4, which is much higher than the R0 of 2–4 estimated for the original version of #SARS-CoV-2 #covid #transmission #presymptomatic #lockdown https://t.co/LAkoX9c8p2
3) For 🧵 with more on the previously recognized role for #presymptomatic transmission (describing studies for wild type/ancestral #SARSCoV2):
https://t.co/km1DE2W7Q5
Transmission heterogeneities & importance of #presymptomatic spread once more emphasized in this @ScienceMagazine study:
~80% secondary cases here traced back to 15% of infections
~83% infections ±5 days from symptom onset (~50% presymptom.)
https://t.co/8KlvKml2KQ
Thread-->
2) In the new analysis the authors estimated the proportion of Delta cases infected due to #presymptomatic transmission:
7 days prior: 2.7%
4 d. prior: 22.5%
- 73.9% in total being before symptom onset
Peak viral load 2.1 days pre symptom onset
Based on 94 transmission pairs
Higher viral load starting @ ~4 #presymptomatic days with #DeltaVariant:
"Extension of contact tracing period to perhaps 4 days prior to symptom onset may be needed considering the high proportion of pre-symptomatic transmission and the high viral load before [symptom] onset"
![JCedernaes's tweet photo. Higher viral load starting @ ~4 #presymptomatic days with #DeltaVariant:
"Extension of contact tracing period to perhaps 4 days prior to symptom onset may be needed considering the high proportion of pre-symptomatic transmission and the high viral load before [symptom] onset" https://t.co/7Njg6CJeKi](https://pbs.twimg.com/media/E9KXDenWYAsjG3o.jpg)
![JCedernaes's tweet photo. Higher viral load starting @ ~4 #presymptomatic days with #DeltaVariant:
"Extension of contact tracing period to perhaps 4 days prior to symptom onset may be needed considering the high proportion of pre-symptomatic transmission and the high viral load before [symptom] onset" https://t.co/7Njg6CJeKi](https://pbs.twimg.com/media/E9KXDNBUUAk16p2.jpg)
Emphasizing Delta's high risk of pre-symptomatic transmission
https://t.co/q4Hqp667hf @Nature
https://t.co/g07TnjGmRF note graphs unvaccinated, vaccinated, prior to symptom onset and comparison w/ ancestral strain
Study conducts systematic review of the pre- and asymptomatic SARS-CoV-2 transmission https://t.co/zXAOQVVmoj @medrxivpreprint @UniofOxford @OxPrimaryCare #SARSCOV2 #COVID19 #covid #coronavirus #pandemic #transmission #asymptomatic #presymptomatic #review
4) As a side note, given the high proportion of #asymptomatic COVID-19 cases & high proportion of #presymptomatic transmission (≥ majority https://t.co/VzmnRjkj7O), viral load may be better for estimating the incubation period.
Proposed model:
https://t.co/YzYXlHtTl0
15) The review by @mugecevik et al. is now out in @CMIJournal: https://t.co/uzeNOi3avQ
Secondary attack rate:
• ~1% for asymptomatic
• ~7% for #presymptomatic
• ~6% for symptomatic #SARSCoV2 infections
(Based on abstract seemingly unchanged vs. preprint in tweet 11-12 above)
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