Top Tweets for #ProxiMeta
New site-specific methylase enzyme & discovery tool (Proxi-RIMS-Seq2) developed in collaboration w/ @NEBiolabs using #ProxiMeta & #RIMSseq2 uncovers methylation patterns characterized directly in #microbiome samples. #VoM2024 More here: https://t.co/vco7CyHmIY

Stoked that this preprint on the @ZymoResearch fecal reference with @PacBio #longread #HiFi #metagenomics and @PhaseGenomics #ProxiMeta is now out! A lot of work has gone into this over the past ~3 years. Thanks to the entire team, but especially @DPortik.
Our new pre-print is live! 🧬🦠🎉
We performed a deep-sequencing experiment using @PacBio HiFi reads (Revio & Sequel IIe) on a pooled human gut reference from @ZymoResearch, with a primary focus on #metagenome assembly.
1/6
https://t.co/ZMGgwDaAWf
Uncovering a bacteriophage’s secret to prolific presence in the human gut w/ #ProxiMeta! New research reveals a special #phage-plasmid lifestyle, broad host range, and more. Congrats @DanicaSchmidtk1 @Angela_Hickey98 @ivanliachko @gsherloc & Bhatt. https://t.co/KmaGTgfv1Z

New @NatureComms publication uncovered phage-host interactions in soil using #ProxiMeta to study the impact of #phages on #bacterial population dynamics. Congrats @RuonanWu01 @KHofmockel @PNNLSoilsSFA @PNNLab @RyanS_McClure @BioDataGanache & team!
https://t.co/69NsJpkxqx
metaBAT2-LR!
@jgi created a new version of metaBAT2 that uses Hi-C data for #metagenomic contig binning. This is super cool!
I've found @PhaseGenomics #ProxiMeta binning (also Hi-C) increases accuracy and total MAGs for @PacBio HiFi assemblies.
https://t.co/YWFVfSLcDi
This study uses #ProxiMeta to link #AMR genes to their genomic, plasmid, or viral host in #microbiome samples. Data is used to track horizontal gene transfer of antimicrobial resistance to Salmonella in chickens. @USDA_ARS @CSUmicrobiome https://t.co/Yz5KOqjx3A
(/4)
Published in @NatureBiotech, breakthrough research, featuring #ProxiMeta Hi-C data, assembled over 400 high-quality MAGs and hundreds of host-viral/plasmid associations from a single fecal sample. @BickhartDerek, @marnixmedema @tplsmith @USDA_ARS https://t.co/lCMR1oBbrx (/2)
Breaking #genome research for #catsoftwitter! Scientists at @UCDavis published a study using our #ProxiMeta Hi-C platform to obtain high-quality MAGs from the fecal #microbiomes of cats. Congrats @ConnieLaBiologa @hollyhganz @jennifergardy @phylogenomics
https://t.co/y7fTKVTNdS

Congrats to Irmarie Cotto (@irmarie_25) for completing their dissertation (supervised by Dr. Ameet Pinto @watermicrobe) on Comammox Bacteria, using #ProxiMeta to deconvolve novel microbial species & strains from wastewater #metagenomes. Check it out here: https://t.co/fwPjhjw2Le
🧀 Say cheese! Researchers used a combination of #ProxiMeta Hi-C & @PacBio to enable genome- & mobilome-resolved #metagenomics in a study on cheese rinds. Congrats @christinacsaak @emilycpierce @racheljdutton @TheRealCong @DPortik @AshbyMere
https://t.co/4AI5wkC2A6

Great example of a "complete" metagenomics study! Isolate sequencing, @PacBio HiFi for metagenome assembly, short reads for mapping, #ProxiMeta from @PhaseGenomics to link MGEs with hosts, and even pangenome analysis. An outstanding roadmap that raises the bar - big congrats!
Recent study uses #ProxiMeta to link #AMR genes to their genomic, plasmid, or viral host in #microbiome samples. Data is used to track horizontal gene transfer of antimicrobial resistance to Salmonella in chickens. Read more here:
https://t.co/g2EJEASJgk @USDA_ARS @CSUmicrobiome

New publication from a research team at @ISUVetMed tracks antimicrobial resistance genes in the gut #microbiome of calves using the #ProxiMeta Hi-C Microbiome Kit. #genomics #resistome #metagenome https://t.co/EYjbffotHk

New paper from @zhangt1968 lab looks at the immense viral diversity in wastewater treatment plants & demonstrates the power of #ProxiMeta Hi-C to identify #phage & affiliate them with their hosts in complex communities, outperforming CRISPR-based methods https://t.co/gOS7bkwRiY
Add a new dimension to your #AMR analysis! The #ProxiMeta platform allows you to track changes in microbial communities and mobile element dynamics over time. https://t.co/pCyUvv95Ui
Did you know that our #ProxiMeta platform for metagenomic analysis is FREE with most kit and service purchases? View some example datasets here: https://t.co/Vh9uglpct6
New publication by Adelumola Oladeinde, Casey Ritz, & team demonstrates the impact of horizontal gene transfer on antimicrobial resistance in infected Broiler Chicks. #ProxiMeta #AMR #microbiome
https://t.co/3hBW2EDOah
The ProxiMeta™ platform outperforms traditional binning methods in a #TBT publication from Maximilian Press et al. (2017) using #ProxiMeta to deconvolve a human fecal #metagenome. #humangenome #biotech
https://t.co/uLUNDzDaUZ

The ProxiMeta™ platform can also be used to understand mobile element dynamics in complex microbial communities over time. One study tracked these dynamics in fecal samples following antibiotic treatment. #microbiome #AMR #ProxiMeta
Read more: https://t.co/ggDvIjOg4f
Want to see how proximity-guided metagenomics works? Here’s a brief animation explaining the process! #ProxiMeta #biotech #scienceanimation #proximityligation #microbiome
https://t.co/PAoj1olT9j
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