Top Tweets for #Sphingolipid
Peters, Wickström et al. show that #sphingolipid #metabolism orchestrates establishment of the hair follicle #StemCell compartment. https://t.co/cvKKpffl0r
📕 From The Year In Cell Biology: https://t.co/XzD74UljkQ
#CellBio2025
A new Science #Immunology study uncovers how protein #palmitoylation and #sphingolipid metabolism control regulated exocytosis in human lymphocytes by targeting cytotoxic granules to lipid rafts in the immune synapse. https://t.co/ZFT5s9F51E
Excited to share our latest study in Metabolism @els_endo, exploring how dysregulated #sphingolipid #metabolism contributes to #liver #fibrosis using #spatial #lipidomics!
Check it out here:
https://t.co/RcZlu0gk4M
Modulating sphingolipid metabolism through genetic manipulation or pharmacological intervention might offer new strategies for managing metabolic diseases and other conditions linked to sphingolipid dysregulation
🔗https://t.co/CQrTVvzdpq
@society_eas @ELS_Cardiology @SL_Biology
Check out new work by @MdSaifurRKhan1 of @RazaniLab @PittVMI & colleagues in @ScienceAdvances showing protective role of #sphingolipid #ceramide (via Ceramide Synthase, CERS2) in #insulin secretion, #T2D #diabetes. Nice combo of clinical & animal studies!
https://t.co/8v9jC3smcP
#Ceramides are key lipids in #skin, crucial for #sphingolipid synthesis and #cell signaling.
Their structure shapes their function in regulating #membrane properties.
Learn more: https://t.co/xMN5PvEcn3
#LipidMetabolism #SkinHealth #LipidClass
Registrations are OPEN!
Join us at 13th iCC & 3rd FEBS Special Meeting on #Sphingolipid Biology – May 25-30, 2025 in Varna 🇧🇬.
Submit your abstracts for a chance to present!
📢Students & postdocs: don't forget to apply for FEBS YTF support!
https://t.co/OK1LsBFCZS
#SLBiol2025
Zahlreiche Krankheiten werden durch einen gestörten #Sphingolipid-Stoffwechsel im #Gehirn verursacht. Ein Forschungsteam der @Uni_WUE hat neue Moleküle zur Visualisierung des Sphingomyelin-Stoffwechsels vorgestellt, was neue Therapiemöglichkeiten eröffnet. https://t.co/PfqqcT9apt
Excited to be attending the XV #Sphingolipid Club Meeting in Erlangen, 🇩🇪
I’ll be presenting our recent findings on #brain #lipidomics & #Alzheimer
Reach out if you’re around!
Is your Monday being *extra* Monday-ish?
Would some free #PlantScience help?
Then we've got good news for you!
Find out how α1-COP modulates #plasmodesmata function in this new #JIPB paper by Iswanto et al.
🔓⬇️
https://t.co/oVXoXsYRxQ @wileyplantsci #Arabidopsis #sphingolipid #desmotubule
Acetylcholine is widely used to test #endothelial function in 🏥 & 🔬🧫, as it can increase nitric oxide production. In our latest @atvbahajournals research letter, we used human arterioles to explore if there is a link between Ach and #sphingolipid signaling.
🌟Key takeaway: ceramide and S1P formation are necessary for Ach-induced nitric oxide production and subsequent arteriolar dilation!
🌟In fact, Ach can directly activate the ceramide forming enzyme NSmase!
Link to article: https://t.co/qd1rQgnqwp
🧐Why is this important!?
This work & our prior study linking ceramide formation with normal flow response in healthy and CAD arterioles (https://t.co/gXUg4af7et) emphasize the importance of ceramide formation in maintaining healthy microvascular function! So we need to be cautious with therapies that aim to lower ceramides as a preventive measure (I.e. analogous to a statin for this pathway).
🤓For more 📖 on how ceramides can be so important but also promote disease in some conditions: https://t.co/06y9X6DAIr
@LabFreed @RachelHLimpert @CVCatMCW @MCW_Research @AHAScience @AHA_Research
Scientists found that the #sphingolipid biosynthesis pathway was commonly ⚡ activated in Th1, Th2, Th17, and iTreg cells and that inhibition of this pathway led to the 👇 suppression of Th17 and #iTreg cell differentiation.
@CommsBio | https://t.co/jz6c4ucecU
🔴 Bernacchioni, @matteoprisi & al. @UNI_FIRENZE characterise the role of #SphingoLipid signalling fostering invasive behaviour of endometrial cells in #Endometriosis:
🔴https://t.co/D1uckRgkKx
📢🧬 In this study, the authors have specifically blocked a key step of #sphingolipid biosynthesis in #𝘊𝘢𝘯𝘥𝘪𝘥𝘢 #𝘨𝘭𝘢𝘣�#𝘨𝘭𝘢𝘣𝘳𝘢𝘵𝘢 by disrupting the orthologs of #ScIpt1 and #ScSkn1.
🔬👉 Discover the results here: https://t.co/4OwWN5TE81
💥Original Article💥
💢Simultaneous structural replacement of the sphingoid long-chain base & sterol in budding yeast💢
✏️By Motohiro Tani & colleagues at @KyushuUniv_EN
➡️https://t.co/KfdJZpaevB
#Saccharomycescerevisiae #sphingolipid #sterol #stresstolerance #structuralbiology
Rubinelli & colleagues found that #endothelial #sphingolipid de novo biosynthesis is necessary to preserve #cerebrovascular homeostasis. Learn more at https://t.co/ASexjk9G4o
@ar_dilorenzo @Anna79037733 @LindaSasset
#Cholesterol-dependent homeostatic regulation of very long chain #sphingolipid synthesis. A new study from Yeongho Kim, Grace Mavodza, Can E. Senkal @Senkal_Lab, and Christopher Burd @YaleCellBio: https://t.co/ySBV8qnlqg
#Metabolism #Biochemistry #membrane #lipid
Latest curated articles👇🏽
📰How the #cGAS–#STING system links #inflammation and cognitive decline(📷)
📰An intestinal #sphingolipid confers intergenerational neuroprotection
🔦Tagging #neurons with light
🔗https://t.co/ghHrjUwVpJ
🙏🏽Thx @Bims_BiomedNews
Up for a road trip?🚗
Sphingolipids act as signaling molecules in many cellular processes. Join us on this adventure to learn more about the #sphingolipid #biosynthetic pathway!🛣️
https://t.co/FHBVK5Mv0t @wileyplantsci #PlantScience #JIPB #Arabidopsis #signaling #PlasmaMembrane
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