Top Tweets for #YCHR
Y-chromosome alteration and its impact on cancer progression and metastasis. #YChr #Cancer #Metastasis #CellularMolecularBiologyLetters
https://t.co/yytbpSBoDG

#YChr #HaplogroupF
The "F"ather of all" NON" Africans !!
Haplogroup F (Y-DNA), also known as F-M89, is a major paternal lineage defined by the M89 mutation. It is the direct ancestor of nearly all Y-chromosome haplogroups found outside of sub-Saharan Africa and is present in over 90–95% of men beyond that region.
#KeyFacts
Time of Origin: Estimated between 43,000 and 62,500 years ago
Place of Origin: Likely in West, South, or Southeast Asia
Defining Mutations: M89, P14, and M213
Main Descendants: F1, F2, F3, and the major clade GHIJK, which includes G, H, I, J, K — and further L, M, N, O, P, Q, R
#Distribution
Haplogroup F and its subclades dominate paternal lineages in Europe, Asia, Oceania, and the Americas. It is extremely rare in sub-Saharan Africa, reinforcing the idea that it arose after or during the early stages of human migration out of Africa. While most lineages have diverged into descendant groups, some unclassified F* types persist at low frequencies in regions such as South Asia, East Asia, and Oceania.
#EvolutionaryImportance
Haplogroup F stands as a foundational node in human paternal ancestry, giving rise to nearly all non-African Y-chromosome lineages. Its descendants spread across continents, shaping much of the modern genetic map.
Haplogroup F's legacy is its central role in the paternal ancestry of most of the world's population outside of Africa.

The Yemeni Coalition for HRs #YCHR, in partnership with @CIHRS_Alerts is organizing a sideline event of #HRC56 entitled #OpenTheRoad in #Yemen.
President of Musaala Org @mahdibalghaith, will be speaking about the suffering of Yemenis due to the continuous closure of main roads.

MONDAY at #HRC56: Join us alongside, @CIHRS_Alerts, @fidh_un and #YCHR for this event on the sidelines of #HRC56, entitled "#OpenTheRoad in #Yemen."
Speakers incl. @MusaalaOrg, @bahia_alsaqqaf of @PASSfoundationY, @ThurayaDammaj and @MayssaAchek.
More info ⬇️

(1) The #Ychr is much more variable among ape species than the #Xchr in terms of alignability, nucleotide substitutions, structural variants, repeats (#TEs and #satellites), and segmental duplications. This is likely due to the lack of inter-chromosomal recombination on #Ychr.
Read our new @Nature paper on 'Complete sequencing & comparative analysis of ape sex chromosomes'. Bonobo, chimpanzee, gorilla, orangutan, and siamang #Xchr & #Ychr are now telomere-to-telomere (#T2T)! A collaboration of the #T2T_Primates_Consortium. 🦧🦍https://t.co/TrgWDw8pfb
It is so great to see Monika Cechova (@biomonika), my former #PhD student, again! We had a fantastic time visiting Mendel Museum in Brno today. I have been hoping to visit this place since high school. Note the chairs with the #Ychr.

New paper "Assessing the Forensic Value of DNA Evidence from Y Chromosomes and Mitogenomes" with @djbalding #forensic #statistics #genetics #ychr #mtdna https://t.co/l88Eg6qljc

I know I have asked this before but I now have data so -
Anyone know of region(s) that are either consistently methylated on the Y chromosome, or consistently methylated in placenta?
#teamplacenta #epigenetics #ychr #dnamethylation #placenta
Read our @OfficialSMBE paper on evolution of great ape 🦧🦍👧 male #fertility ampliconic genes on the #Ychr. Their copy number evolves fast, but expression in testis - slowly. Collaboration with @rahul_vegesna, @MTdellarte, @frozenzoo, R. Campos Sanchez, @pashadag, M. DeGiorgio.
GBE latest: Ampliconic genes on the great ape Y chromosomes: Rapid evolution of copy number but conservation of expression levels https://t.co/O0MCduCIr2
Separated at birth, these two furry 🦧 were adopted by two #PhD students, @biomonika & @rahul_vegesna, who both recently defended and co-authored our recent preprint on the #evolution of the #Ychr in great #apes:
https://t.co/OnxQUYLsxn

“The activity of our NGO is aimed at protecting human rights, including the rights of national minorities. Yezidi Center for Human Rights is ready to cooperate both with individuals and organizations that have a similar goal, ” @sashasultanyan
#YCHR #yezidis #armenia
We held a seminar on how to deal with discrimination in the workplace learning the principles of local legislation and the International Labour Organization Convention.
#YCHR #humanrights #yezidis #armenia

K. Mckernan #SMRTLeiden: the #Ychr is yet to be sequenced for #Cannabis. We are looking forward to these results! @biomonika
Represenatatives of "Yezidi Center for Human Rights" Sashik Sultanyan and Isabel Broian discussed the issues of National Minorities in Armenia and the new Law on National Minorities at Human Rights House Yerevan #Yezidis #Yazidis #HumanRights #YCHR

The Fountain-of-Youth Hypothesis: Occasional sex reversal prevents #YChr degeneration.
@biomonika @md5sam @MTdellarte
https://t.co/BtHgCsbDp1
Two men rarely have the same copy number of ampliconic genes on the #Ychr. Such high #diversity for ampliconic genes contradicts low nucleotide diversity found on the #Ychr.
Our paper in collaboration with @A_A_Zaidi @MTdellarte @alljustatoms and Mike DeGiorgio. https://t.co/02ctv1hk2D
GBE latest: High levels of copy number variation of ampliconic genes across major human Y haplogroups https://t.co/YeljMAmJrw
#livereport @PenerbangRoket lg check sound sekarang! Ayo saksikan aksi mrk!
#ychr #ngeham #sahabatham #lenteraham

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