Top Tweets for #brilinta
Which are the key points of the recent article in the BMJ challenging the results of the landmark PLATO trial on ticagrelor in acute coronary syndromes? https://t.co/aijXngqRzG #Brilinta #Brilique #Ticagrelor @bmj_latest @AstraZeneca
1. Widespread Use and Cost - Ticagrelor is widely recommended for acute coronary syndrome but incurs significant public expenditure, accounting for two-thirds of US P2Y12 inhibitor costs in 2022, despite representing less than 10% of prescriptions.
2. Efficacy Doubts - While the PLATO trial showed ticagrelor’s superiority to clopidogrel with a 16% relative risk reduction in primary endpoints, subsequent studies have failed to replicate these results, often showing similar efficacy but higher rates of bleeding and dyspnea.
3. FDA Approval Controversy - The drug was approved despite strong objections from FDA scientific reviewers, who raised concerns about the reliability of the PLATO trial data, particularly regarding US-specific results that favored clopidogrel.
Ep5 of #KnowYourCompany series explore the world of #AstraZeneca. Discover AZ's innovative treatments in #oncology, #cardiovascular, #renal & #metabolism, & #respiratory diseases, including #Tagrisso, #Brilinta, & #Farxiga & many more in the video below #companyprofile
داروی #Brilinta آسترازنکا که کمیاب بود و داروخونه ۱۳ آبان و ارتش بجز دو مرتبه که موفق شدم ازشون بگیرم و اکثر مواقع نداشتن و قیمتش به ازای هر ۵۶ تا دونه ۲۱۰ تومن بود رو توی همون دوران از دلال می گرفتم ۳۰۰ تومن؛ دارویی که برچسب واردات خورده بود و باید تو داروخونه می بود._
THALES data published. Benefit shown for $AZN #Brilinta (#ticagrelor) + aspirin vs aspirin alone in acute ischemic stroke or transient ischemic attack. Supports sNDA for the reduction of subsequent stroke in this pop; granted priority review by FDA. https://t.co/P7zFli5Ppa
The @US_FDA approved #Brilinta @AstraZeneca to reduce the risk for a first MI or #stroke in high-risk patients with coronary artery disease. https://t.co/Slurphu2cq @DLBHATTMD @BrighamWomens #heartdisease #cardiology
The @US_FDA approved #Brilinta @AstraZeneca to reduce the risk for a first MI or #stroke in high-risk patients with coronary artery disease. https://t.co/Slurphu2cq @DLBHATTMD @BrighamWomens #heartdisease #cardiology
ICYMI: Yesterday, @AstraZenecaUS announced the FDA approved ticagrelor (#BRILINTA) DAPT to reduce the risk of first heart attack or stroke event in patients with coronary artery disease with no history of CVD or #stroke.
#Cardiotwitter
https://t.co/Qyok4fG3dj
This week's Fox content brought to you by: @newdayusa @amgen #otezla @carvana @comcast @xfinity @tmobile @astrazeneca @symbicort #brilinta @toyota #DropFox
Significant paper on the cost of misinformation. Basically, one standard deviation more viewership of Sean Hannity (denied seriousness of COVID) versus Tucker Carlson (took the pandemic seriously) is associated with in 20% more deaths at the county-level. https://t.co/7wDDXVOiu6
So excited for my first article published in @annalsthorsurg!
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Patient with #STEMI receives a loading dose of #Brilinta - cath shows multivessel CAD and patient becomes hemodynamically unstable. What’s next? Time is #myocardium!
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@UjjwalRastogiMD @GianlucaTorreg1
Results from the #TWILIGHT trial showed that #BRILINTA #monotherapy reduced the #risk of clinically relevant #bleeding. Dr. Roxana Mehran and Dr. Usman Baber weigh in: https://t.co/TurNbtttya
Results from the #TWILIGHT trial showed that #BRILINTA #monotherapy reduced the #risk of clinically relevant #bleeding. Dr. Roxana Mehran and Dr. Usman Baber weigh in: https://t.co/5U9uMnhZCW
Come December and there will be Ticagrelor war. This is a multimillion dollar molecule and all the Indian pharma companies are vying for supremacy. It is that bio similar with the best bioequivalence of that of original molecule will be the winner.#Brilliant #brilinta
Cutting aspirin from the #ticagrelor (#Brilinta)-based dual antiplatelet therapy (#DAPT) regimen after 3 months was safer for high-risk stent recipients, the #TWILIGHT trial showed. #TCT2019 https://t.co/s6qpRlfisC https://t.co/rehgClKb7b
@Ishback @wheeliedealer @marben100 @USabadini @talygarntom @dhovekamp42 @MedTechpreneur @A1Mhigh @DianaEPatterson @mattbird55 @Financial_Orbit @AstraZeneca @SandyMidd @contrariansmind @annabelbrodies @sunsuneti1 @categoryx @FiercePharma @AstraZenecaUS @FoolishFinances @woodfordfunds @Telegraph @DigitalLookNews @CarlyHFierce @ByMadeleineA @BionestPartners @biogerontology @bradloncar @MY21_Oracle @AIMInvestor1978 @Aendryr @Accendo_Mike @TheIdleInvestor @RegHoare @fwpharma @PharmaReview @CNBC @wef @MikeQuindazzi @Sharecastcom @PharmaScrip @Vantageanalysis @CNNBusiness @Accenture @pharmaphorum @blackrock #AZN+2% £75.20 Phase III #Brilinta reduced the risk of #cardiovascular events in patients w/ coronary artery disease & type-2 #diabetes✅
Phase III #Farxiga significantly reduced both the incidence of cardiovascular death & the worsening of heart failure✅
https://t.co/pRRm18hjeI
This is fascinating.... #Ticagrelor or #Brilinta in Conventional #Antiplatelet Dosages has Antibacterial affect Against Antibiotic-Resistant Gram-Positive Bacteria | #Cardiology | #JAMA #AHAFIT #ACCFIT #AHA
The antiplatelet drug ticagrelor has bactericidal activity against Gram-positive bacteria, including antibiotic resistant strains. https://t.co/naUeeOhhWV
An antidote to #ticagrelor (#Brilinta) provided quick and sustained reversal of the #antiplatelet effects in a small phase I trial, according to researchers .
Read more:
https://t.co/H2iIJkvxyx
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