Top Tweets for #zzFIRST
Final results from #ZZFIRST: A randomized phase 2 trial of enzalutamide and talazoparib in mHNPC. Presentation by @quimmateo @VHIO. #ASCO26 written coverage by @chavarriagaj @PSH_Urology > https://t.co/JH9oUp7K31 @ASCO

#ZZFIRST is a phase 2 for high volume mHSPC pts randomized 2:1 to ADT/enza with or without talazoparib.
On treatment biopsy collected prior to randomizing and non-HRR patients allowed. 12 mo PSA <0.2 was 73% with enza/tala, 64% with enza (p<0.001).
Two of 37 patients on talazoparib did develop AML, an important reminder about long term PARPi risk.
#ASCO26 #ProstateCancer @OncoDailyGU @OncoAlert @urotoday @GUOncologyNow

#ASCO26 | Noves dades de #TALAPRO3 (publicat a @NEJM) i #ZZFIRST reforcen la medicina de precisió en càncer de pròstata metastàtic.
Liderat per @quimmateo, el Grup de Càncer de Pròstata del #VHIO ha tingut un paper clau en tots dos estudis, incloent-hi el lideratge de l’assaig #ZZFIRST, promogut per @wearemedisr
➡️ https://t.co/WWnAs2Gkjf

#ASCO26 | Nuevos datos de #TALAPRO3 (publicado en @NEJM) y #ZZFIRST refuerzan el papel de la medicina de precisión en cáncer de próstata metastásico.
Liderado por @quimmateo, el papel Grupo de Cáncer de Próstata del #VHIO fue clave en ambos estudios, incluyendo el liderazgo del ensayo académico ZZFIRST, promovido por @wearemedisr
➡️ https://t.co/Co1XsSgM7b

#ASCO26 | New data from #TALAPRO3 (published in @NEJM) and #ZZFIRST strengthen precision medicine in metastatic prostate cancer.
Led by @quimmateo, the #VHIO Prostate Cancer Group played a key role in both studies, including leadership of the investigator-initiated ZZFIRST trial sponsored by @wearemedisr.
➡️ https://t.co/9pryvB1IyB

#MEDSIRatESMO presenting #ZZFirst!
The study assesses the antitumor activity of talazoparib combined with enzalutamide and ADT, measured by confirmed PSA complete response, in patients with metastatic hormone-naïve prostate cancer👨🔬 🧪
#CancerResearch #Innovation #prostatecancer

First results from #ZZFIRST: a randomized phase II trial of enzalutamide with or without talazoparib in metastatic hormone-naïve #ProstateCancer. Presented by @quimmateo @VHIO. #ESMO24 written coverage by @chavarriagaj > https://t.co/cubfAkARvL @myESMO

A randomized phase 2 trial to evaluate the antitumor activity of enzalutamide and talazoparib for the treatment of metastatic hormone-naïve #ProstateCancer: #ZZFIRST. Presentation by @quimmateo @VHIO. #GU22 written coverage by @WallisCJD > https://t.co/xdloPfCTS7 @ASCO

We excited to present the trial designs of #ZZFIRST for the management of patients with metastatic hormone-naïve prostate cancer (mHNPC) and #ORPHEUS, aiming to help patients with penile squamous cell carcinoma (PSqCC) at @ASCO #GU22 next week!
#prostatecancer #GUmalignancies

For #Movember we want to highlight our #ZZFirst phase II trial of enzalutamide + talazoparib for hormone sensitive #ProstateCancer. It explores the possibility of expanding the population of patients benefiting from PARP inhibition beyond those with only DDR genomic defects.

Os presentamos el estudio #ZZFIRST. El objetivo de este ensayo es evaluar la actividad antitumoral del tratamiento con Enzalutamida y Talazoparib en pacientes con cáncer de próstata metastásico sin terapia hormonal previa.
¿Quieres saber más? 👇
#ConviveConElCáncer #MEDSIR
On the last week of #MOVEMBER, we share the #ZZFIRST clinical trial.
A multicenter, open-label, randomized, two-arm, phase II study to evaluate the efficacy and safety of talazoparib in combination with enzalutamide in patients with metastatic hormone-naïve #prostatecancer.
En #MOVEMBER, queremos compartir nuestro trabajo en investigación de cáncer en pacientes con #cáncerdeprostata a través del ensayo clínico #ZZFIRST.
Para más información llama por teléfono al +34932711044 o visita el aparatado de ensayos clínicos en nuestra web.
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