Heather K. Le Bleu, PhD

Dream Big.

[Heather K. Le Bleu, PhD @HeatherBleu]

New publication‼️
Unique voltage-gated calcium channels and exceptional zebrafish fin regeneration.

Welcome to connect with me. ☺️

https://t.co/4KkYjEQxZh

[Heather K. Le Bleu, PhD @HeatherBleu]

@Dev_journal

[Heather K. Le Bleu, PhD @HeatherBleu]

New publication‼���
Unique voltage-gated calcium channels and exceptional zebrafish fin regeneration.

Welcome to connect with me. ☺️

https://t.co/4KkYjEQxZh

[Heather K. Le Bleu, PhD @HeatherBleu]

@GurparneetSohi @georgiosster @vineeth1126 @SabaAlvand @TheNRMP Congrats! 🎉 Yay to you and your exciting new journey! 😃

[Heather K. Le Bleu, PhD @HeatherBleu]

My preprint is now posted with some minor updates! Glad to share this work and grateful to everyone who contributed. Check it out here: https://t.co/mKj7USA9jt

[biorxiv_devbio @biorxiv_devbio]

Voltage-gated calcium channels generate blastema Ca2+ fluxes restraining zebrafish fin regenerative outgrowth https://t.co/enj4WgohH0 #biorxiv_devbio

[Zebrafish Rock! @ZebrafishRock]

Preprints:

Behavior

@SarahStednitz @LabEthan (social interaction/ multisensory bases)
https://t.co/qqBPWgrEFc

@RoyHarpaz @EngertLab (social behavior/ virtual-reality experiments)
https://t.co/LPyGYbpqpt

Disease Models

@gaattagca @KizilLab (Fetal Alcohol Spectrum Disorders/ gene expression changes)
https://t.co/H8lT9D1oFs

@MathuruLab (Alcohol use disorders, neurogenetics, chrna3)
https://t.co/OY4opQdIOJ

@Gianteaterofant (iPSC/ FOXG1 Syndrome/ mitochondrial translation)
https://t.co/hmpVjCjWXV

@LabBerman (Li-Fraumeni syndrome/ p53/ R217H and R242H)
https://t.co/OH3JUl9j9F

Nervous System

@CharlieDowell4 (motoneuron/ kinematically distinct saccades/ hunting)
https://t.co/WRZ68llqNw

@slewzeus (notochord/ endochondral bone lengthening)
https://t.co/pCu6svuQJA

@Fish4Brains (neural activity, whole-brain activity mapping, histology, microscopy, cfos)
https://t.co/CFIXDNwJGm

@summerbthyme (Neuroscience, microexon splicing, brain development)
https://t.co/7v01k3vxJZ

Embryogenesis/Organogenesis

@schierlab (embryogenesis, whole embryo imaging, weMERFISH)
https://t.co/EZ6l2wEVwx

@schierlab (transcription factors, chromatin accessibility, vertebrate embryogenesis)
https://t.co/NRVafGJkvE

@MTLeeLab (embryonic genome activation, maternal-to-zygotic transition)
https://t.co/cbDr8bzydE

@LarsAllanLarsen @t_soren (development, heart, tgf-beta, signaling)
https://t.co/JPZRyHzAkh

@GioeleLaManno (embryogenesis, metabolic programs. Whole-organism metabolomic atlases)
https://t.co/ZP9EviRiHa

Aging

@LeibnizFLI (killifish/ epigenetics/ lifespan)
https://t.co/b4jDGZBHQP

Cell Biology

@StratmanLab (intron splicing/ ciliogenesis/ axis patterning)
https://t.co/lHV6Bq1gM4

@CaraMoravec & Francisco Pelegri @UWMadison (gpRNPs, cellular division, embryo, Survivin)
https://t.co/maj2gM2ARd

@McmenaminLab (Fin shape/ embryonic fin fold)
https://t.co/4ODs1mFPgg

Infection and Inflammation

@TFordRobertson (live imaging/ leukocytes/ tissue-specific migration)
https://t.co/8WF4RL2mmm

Regeneration

@StankLab (regeneration, K+ channels, Ca2+, cacna1g, fins)
https://t.co/yI0swkj2LX

Technology and Tools

@stefarber (forward genetic screening, chemical mutagenesis, WheresWalker)
https://t.co/a9RxiRvWu7

Reviews & Perspectives:

@ZfishHayes @SheckyFeinblatt (glioblastoma modeling/ microglia)
https://t.co/n3RTc3RG9F

@Alex_Brombin @EdinUni_IGC (melanocytes/ neural crest/ MITF)
https://t.co/7NcQmNjkv8

@LeaLescouzeres @KessenPatten (Amyotrophic lateral sclerosis/ chemical genetics/ drug discovery)
https://t.co/gdKBJHDzNP

@Tanaxolotl @Ken_Pos_Lab (regeneration)
https://t.co/Drd9fYm6eT

@ivosena @emiliapsantos (Cichlids, development diversity, field work)
https://t.co/blRgjlcsOY

@BGI_Research (spatiotemporal omics)
https://t.co/Mk846HPLcb

Protocols, Methods & Tools:

@psych_genes (drug discovery, neuroscience)
https://t.co/Elb4jK9Fq8

4 of 5

[Heather K. Le Bleu, PhD @HeatherBleu]

I am pleased to share this new preprint with all of you!

https://t.co/ISQZGgKubL

[Heather K. Le Bleu, PhD @HeatherBleu]

In Kansas City, MO for the Stowers Research Conference on Stem and Regenerative Biology. I look forward to engaging with people and will be giving a short talk on Friday! @Stowers_SRC

[Heather K. Le Bleu, PhD @HeatherBleu]

Back on the East Coast for the GRS/ GRC Developmental Biology conference. I look forward to speaking one-on-one with people at my poster. I will be giving a short talk on Tuesday, as well!

[Heather K. Le Bleu, PhD @HeatherBleu]

What a great a summer it has been conducting research together! Thank you @uoUROP

[UO Undergraduate Research @uoUROP]

This week we are highlighting the 2022 O’Day Fellowship recipients.

Meet Rea Kioussi and Heather Le Bleu (@HeatherBleu), who are working together in the Stankunas Lab (@StankLab).

[ArtSci Oregon @ArtsciOregon]

#SciArtTuesday from @HeatherBleu: "Chimera zebrafish that is composed of two genetically distinct types of cells. Dashed red line outlines overgrown fin tissue that consists of donor cells. This research investigates how organ size and shape is controlled." #ResearchAsArt #SciArt

[UOIMB Publications @uoimb_pubs]

longfin causes cis-ectopic expression of the kcnh2a ether-a-go-go K+ channel to autonomously prolong fin outgrowth https://t.co/uBSnSjDqI3

[Nathan Lawson @LawsonZFLab]

Update on our #zebrafish #transcriptome. Fixed GTF for more recent @10xGenomics cellranger versions. Apparently sort order matters. Updated GTF at https://t.co/o4DgTBQEjm. Thanks to @HeatherBleu et al. in @StankLab, @biyonur here @UmassMedical Biocore for troubleshooting.

[KamalLab Fadia Kamal @KamalLab5]

Time to expand the lab! Looking for a technician and a postdoc interested in osteoarthritis and cartilage research 🦵

[NIAMS @NIH_NIAMS]

“Paroxetine-mediated GRK2 inhibition is a disease-modifying treatment for osteoarthritis” https://t.co/m6ATfkGAfg Abstract only. Full access requires subscription or payment. #NIAMSResearch @PennState @ScienceTM Other funding: @NIDDKgov @ncats_nih_gov @CureArthritis

[recovery&renewal @recover2renew]

Common #antidepressant may be first-ever treatment for osteoarthritis 😳😳👇 #Paroxetine ⚠️⚠️

https://t.co/C3QjrmCgu2 via @medical_xpress

[Heather K. Le Bleu, PhD @HeatherBleu]

👏🏻👏🏻👏🏻

[Science Magazine @ScienceMagazine]

The FDA-approved antidepressant #paroxetine can halt the progression of #osteoarthritis and regenerate damaged cartilage in the joints of mice, according to a new study from @ScienceTM. ($) https://t.co/oy6ImvxiTi

[Science Magazine @ScienceMagazine]

The FDA-approved antidepressant #paroxetine can halt the progression of #osteoarthritis and regenerate damaged cartilage in the joints of mice, according to a new study from @ScienceTM. ($) https://t.co/oy6ImvxiTi

[Biotech @BiotechRetweets]

Antidepressant Could Represent First Disease-Modifying Treatment for Osteoarthritis💊🦴🦵🏽

@PennStHershey scientists have found that the antidepressant paroxetine can stop the progression of osteoarthritis, and regenerate damaged cartilage in the joints of mice.

[Penn State Health @PennStHershey]

New #research from @penn_state College of Medicine researchers in @ScienceTM shows that a commonly used anti-depressant may also be able to prevent cartilage from breaking down and instead regenerate in #osteoarthritis. https://t.co/8LOJhziVOs