In our latest preprint, @OPIGlets DPhil student @GuyDurant2 et al. benchmark machine learning-based scoring functions and release a new toolkit (ToolBoxSF) to robustly interrogate performance & determine the effect of dataset biases on predictions
https://t.co/qIlBbyySFT
Dan Nissley contributed molecular dynamics simulations & analysis to a new biotechnology that measures "antibody reach" (i.e. the distance spanned in bivalent binding), a property with strong links to neutralisation activity. @biorxiv: https://t.co/AFZwOi0qNi
Thrilled to be leading this international, multidisciplinary team of TCR Matchmakers that made the #Grandchallenge shortlist. We look forward to combining immunology, engineering, and AI to address pairing TCRs with antigens, a key problem in our field. @CancerGrand
A high-affinity human TCR-like antibody detects celiac disease gluten peptide–MHC complexes and inhibits T cell activation | Science Immunology https://t.co/dPhzPe7NIF
We developed a new multivalent mRNA vaccine against all known influenza virus subtypes. Our study describing the vaccine was just published in @ScienceMagazine. 1/n
https://t.co/HxTKm47EC3
Excited to share our most recent piece of work at @OPIGlets : ImmuneBuilder, a set of deep learning based tools to predict the structure of antibodies, nanobodies and TCRs. (https://t.co/WMDRNBqysB)
Our new tool, KA-Search, allows exhaustive yet efficient antibody mining through billions of natural sequences (from OAS and/or your private data), enabling new avenues in function & immunogenicity prediction. Work led by @HegelundOlsen and @brennanaba.
https://t.co/xSt8si8lpW
Very pleased share our new study :A systems approach evaluating the impact of SARS-CoV-2 variant of concern mutations on CD8+ T cell responses https://t.co/GZYLVqB6oq
BIOS — Top 100 TechBio VC Funds 🧬
As TechBio reaches critical mass, we thought it time to centralize the world of TechBio VC into one sheet
We hope this database becomes a useful resource & serves as a go to for founders raising VC Funding…
https://t.co/MA7xN3rmpc
Let's talk about MONEY.
Some Ph.D. students never worry about it, some Ph.D. students are worried about it all the time.
I am sharing what my monthly looks like as a CS Ph.D. student at Stanford and how I think about my financial future.
https://t.co/nbUDlOz4e1
Among billions of potential microbiome epitopes hide few immunodominant 'keystone' epitopes recognized by T cells. Out today in @ImmunityCP, we discover keystone epitopes and show T cell responses to reflect intestinal immune health. https://t.co/YE9zHrd3y9
5 years ago, I proposed using #DeepLearning to predict response to immunotherapy in TCR-Seq.
🧬🧬🧬🧬
Last year, we published #DeepTCR. Today, I am proud to share its application in cancer immunology, now out in @ScienceAdvances#ScienceResearch
🔶🔷🔶🔷
https://t.co/VRxPqwZP5F