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@BradStanfieldMD @CharlesMBrenner @johnhemming4mp Has anybody said this trial result is grounds for changing current guidelines?

This is bizarre

It’s like one side of the conversation (you) is saying stop unethically telling me to prescribe NR to my PAD patients

The other side is just saying this trial result isn’t nothing

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@BradStanfieldMD Dr Stanfield I’ve seen you be pretty even handed in the past.

But downplaying a 2% gain vs a 3% loss (that’s a total delta 5%) walk distance in just 6 months, doesn’t seem like something to totally disregard.

Also seems like you’re overstating the hype here (what hype?).

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@CharlesMBrenner Who gives NADH the electron?

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@bryan_johnson I think you once said you can run successful N=1 trials, to me this supports that and is pretty neat. You had reasons why you tried HGH, and now you’re course correcting based on evidence. To me this says that you’re just willing to risk trying stuff for the benefit of others.

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,,,,,chameleon
you,go
you,go
#misheardlyrics #tonightshow

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@CharlesMBrenner @RaisingNad Can you say if you’re talking about the US? Or just Korea?

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@CaltransDist3 @nevadadot @TownofTruckee @CHP_Truckee @NevadaCountyCA Been stopped near Blue Canyon for almost 2.5hrs. The vast majority were driving a sensible speed, although some were following like it was dry pavement. Then a very small minority were passing and going way too fast. So much that I was not surprised at all when this happened.

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@bryan_johnson But probability of succeeding in your main 4 areas isn’t linearly related to motivation. Often times a little nudge can push you into the success zone. I take issue with the term “magic pills” but could supplements be a nudge factor that could make the difference for many people?

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@elonmusk Everyone relax, this is just a neat trick to count how many bots the WEF controls.

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@CharlesMBrenner @JoeCannonMS @kevinnbass Could you provide any more color on the emerging DNA repair story that you mentioned a few months ago?

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@mkaeberlein To recap: you think all the good data on NR isn’t enough to justify taking it. But you also think it is enough to justify very long and large scale (aka very expensive) trials? Did people start taking 1g of vitamin C per day before multi-year trials published at that dose?

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@mkaeberlein @CharlesMBrenner Aren’t you misrepresenting the state and rate of NR research when you use first marketing date as your point of reference? 82% of articles on PubMed for the last 10yrs, published in the last 5yrs. Seems you’re trying to paint it like all should be known by now but it’s early days

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@elonmusk This tweet is Igor approved

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@DrKeithRoach I’m sincere when I say I mean this respectfully. But “nope” is so reductive that I’m unsure if it’s worth replying. I don’t know if you are thinking deeply about this. Are you aware that there are major issues with the way that paper is being portrayed? https://t.co/yHm5pKrGBM

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@DrKeithRoach wondering if you would reconsider your safety opinion on NR https://t.co/SiHTsHWnTh given that the brand Tru Niagen is GRAS? Also are you aware of this study? https://t.co/AhUpamPugK

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@Valuable @Mike_Walls_ @hubermanlab @BradStanfieldMD @CharlesMBrenner Was a p value given? Did they say this was statistically significant?

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@CharlesMBrenner @TowerCancer @cityofhope Is this part of the dna repair cancer story you mentioned on a podcast recently?

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@NaturalShrimp Don’t be afraid to be bold and coin a new term. Beyond Meat did this. NaturalShrimp - USA Eco Grown/Farmed. NS - Radically Grown. Ultimate Eco NS. NS - Tank to Table. NS - Evolved Choice. NS - Eco Choice. Choice has a nice double meaning when paired with the right word.

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@NaturalShrimp Is NS + 2 words the limit? If so, every single word needs to inspire ppl to ask what is unique about this product? IMO harvest inspires nothing and select merely tries to reinforce quality. Don’t you want people to understand they are saving the oceans by buying Natural Shrimp?

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@CharlesMBrenner It’s often better to ask people questions you already know the answers to, than ones you don’t. Use this trick to find an honest mechanic. But best case scenario is when you get an answer that’s better than the one you thought you already had: you upgrade your view of the word.

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@rwsobol @Cancers_MDPI This seems really interesting. Care to do an explanation thread for us laypeople?