Immorta Bio

REVERSE AGING. ELIMINATE CANCER. REJUVENATE ORGANS.

[Immorta Bio @ImmortaBio]

Paper published in prestigious Journal of Translational Medicine...using antiaging vaccine to stop #cancer

Successful treatment of #glioma #breastcancer #lungcancer and #pancreaticcancer with #senolytic #immunotherapy by #immortabio

#longevity

https://t.co/4OT8fqf6lo

[Aleksandr Litvinenko @AleksandrL14676]

I reviewed the medications' performance across all dimensions:
SenoVax™: Informational Plan- 98.5%
Material Plan - 100%
Energy Plan - 99.5%
StemCellRevivify: Informational - 99.5%
Material Plan - 100%
Energy Plan - 99%
Conclusion: @immortabio's medications are living and work consistently across all dimensions. You need to urgently accelerate their further human trials and launch them into production.

[P. E. Sottas @pesottas]

@exosome @ImmortaBio Agreed. That organism-level logic is exactly why we built BlueBird the way we did.

[Andrew Caravello, DO @andrewcaravello]

🧠 Braelyn is 18 years old and fighting #glioblastoma. #NWBO #DCVax #EmoryProton #UCLA #GBM #ProtonTherapy #BraelynStrong

Her family has built a science-driven treatment plan and they are executing it in real time against real setbacks.

📄 I published a detailed scientific analysis tracing why proton radiation and dendritic cell vaccination are not two separate treatments but a single integrated architecture:

https://t.co/8Px0yEOYS0

"The Dual Dividend" assembles 74 peer-reviewed sources across Nature, Immunity, The Lancet, JAMA Oncology, and the Journal of Clinical Investigation. Here is what it shows:

⚡ THE DUAL DIVIDEND

Proton radiation delivers two simultaneous benefits. It preserves the immune substrate the vaccine needs: monocytes, CD4+ T cells, NK cells, TCR diversity, lymph node architecture. And it conditions the tumor for immune recognition: calreticulin exposure, MHC-I upregulation, 30 consecutive days of cGAS-STING activation, blood-brain barrier opening, and chemokine reprogramming.

Photon radiation generates the same tumor signals then destroys the immune cells that would respond. The signal without the receiver is noise.

📊 KEY EVIDENCE

Frank Phase III (Lancet 2026): first randomized survival proof for protons in any cancer. 5-year OS 90.9% vs 81.0% (HR 0.58, P = 0.045)

Mohan Phase II in GBM: G3+ lymphopenia 14% proton vs 39% photon. Female sex = strongest predictor (OR 6.2, P = 0.003)

Coupey 2026: proton radiation caused zero myeloid depletion. Photons halved the myeloid compartment in 12 hours. Monocytes are what the vaccine is made from

Lei CRISPR proof: the licensing circuit requires CD40L AND IFNβ simultaneously. Photon-depleted CD4+ = circuit FALSE at first node

DCVax-L Phase III: 331 patients, mOS 19.3 vs 16.5 mo (HR 0.80, P = 0.002). The only DC vaccine with Phase III survival evidence in GBM

🔬 THE LICENSING CIRCUIT

The analysis maps a Boolean dependency at the center of vaccine efficacy: CD4+ T cells must deliver two signals simultaneously to license cDC1 dendritic cells for cross-presentation. If CD4+ cells are depleted by photon radiation, the entire downstream cascade (IL-12p70 production, CD8+ T cell priming, epitope spreading) cannot initiate. The vaccine arrives but no one can receive the instruction. Proton radiation keeps that gate open.

🔄 THE REFRAME

Most oncologists still view proton therapy as simply "less toxic radiation." Many families are told it is unnecessary or equivalent to standard photon treatment. Braelyn's family knew better and sought proton therapy from the start. When the proton center in Charlotte declined her case because of its complexity, it felt like a setback. It was not. Dr. Michels personally called Emory, one of the most advanced proton centers in the country, and they agreed to treat her. The science shows that for a patient who will receive a dendritic cell vaccine, proton radiation is not a luxury or a preference. It is a mechanistic prerequisite. It preserves the very cells the vaccine is manufactured from and the very cells the vaccine must teach. What looked like a closed door led directly to a better one.

🧬 WHY BRAELYN

Her situation maps directly onto this architecture:

MGMT-unmethylated: temozolomide offers less benefit. Her immune system is the primary therapeutic mechanism

Female: the Mohan trial specifically indicates proton therapy for women (OR 6.2)

Age 18: still has active thymic function, faster immune reconstitution, and broader T cell diversity than older patients. These are advantages proton radiation preserves and photons would erode

🏥 THIS WEEK

Her local oncologist Dr. Michels personally called #Emory to secure proton radiation after Charlotte declined. Her family completed their first telehealth with Dr. Ashkan in the UK to plan the autologous dendritic cell vaccine (ADCV), the same platform tested in the #DCVax Phase III trial, through compassionate use. Dr. Liau at #UCLA is coordinating directly and is emerging as a key figure in Braelyn's care.

🗓️ THE PATH

Proton radiation at Emory → recovery window with steroid taper → leukapheresis to collect immune cells → ADCV manufactured from her own blood → vaccination series beginning in the UK in early June

Every step has a defined biological purpose. Every decision connects to the next.

💛 THE ASK

But the costs are real. Six weeks of daily proton treatment in Atlanta. International travel to the UK. Compassionate use coordination. Medical expenses no insurance fully covers. All for a young woman whose life is just beginning.

This family is not waiting for someone to save them. They have been building this from day one, seeking out every treatment, coordinating across three countries, assembling a team of physicians who believe in this approach. They just need help getting there.

To the #NWBO and #DCVax community, to every shareholder, every patient family, every person who understands what this platform means: Braelyn's treatment plan is built on the science you have supported. This is what it looks like when the science reaches a patient.

Please share this post. Please help if you are able.

🧡 https://t.co/zBy1J0lHRe

#DCVax #NWBO #Glioblastoma #ProtonTherapy #EmoryProton #UCLA #WinshipCancer #DendriticCell #Immunotherapy #ADCV #BraelynStrong

Follow Braelyn’s journey and support her family: @HollensbeAmanda

[Dr. Thomas Ichim @exosome]

#catholic #biotech

https://t.co/vJ30Flmn4X

[Immorta Bio @ImmortaBio]

@RWyoral @exosome @LongevitySNews

[ETERNAL 🙏❤️ @RWyoral]

@exosome @LongevitySNews @ImmortaBio Right here you kinda look like Jim Belushi

[Dr. Thomas Ichim @exosome]

@LongevitySNews is the best !!

thank you for this Amazing video

#senovax #immortabio @ImmortaBio

$ibrx $nwbo

https://t.co/Zifc01aTYz

[ATLnsider @ATLnsider]

@andrewcaravello @metacollectiveG Dr. Zivic truly cared about his patients & all solid tumor cancer patients worldwide. He championed $NWBO & #DCVax approval. I will miss him. Prayers & condolences to his family.

[Louisa Nicola @louisanicola_]

Repetition strengthens specific neural pathways through synaptic plasticity, so the circuits you activate over and over literally become more efficient and easier for the brain to fire. That’s why consistent practice makes skills and thoughts feel automatic over time.

[Immorta Bio @ImmortaBio]

@andrewcaravello @metacollectiveG Deepest condolences. We really enjoyed interacting with him.

[Andrew Caravello, DO @andrewcaravello]

Heartfelt condolences to the family and friends of Dr. Greg Zivic, a true friend and fearless advocate for truth. He helped spread the word about $NWBO and all it stood for with conviction and integrity. He will be greatly missed. Rest in peace, Dr. Zivic @metacollectiveG 😞😞😞

[David Schull @davidschull]

When in the #305 we rep good friends and family @BiotechTV @bradloncar @russopartners

[Immorta Bio @ImmortaBio]

@agingdoc1 @A4MEvents Congratulations !!!

[Agingdoc🩺Dr David Barzilai🔔MD PhD MS MBA DipABLM @agingdoc1]

What an incredible year—huge thanks to Storyful

Looking ahead to 2026 👇
• TEDx talk release
• Podcast interviews (incl @A4MEvents)
• Judging
• Publishing (author & editor)
• Producing (TBA)
• Longevity consulting, advisory boards & more fun
Grateful for all the support🙏

[Danny Medina 圣灵 @caveman3000_]

Yo @davidasinclair what are you thoughts on this, I heard you say you would revive senesent cells instead of getting rid of them and how does it compare to what you're doing, could @ImmortaBio be at the forefront of true age reversing/anti aging etc

[Immorta Bio @ImmortaBio]

Senolytic #immunotherapy....the future is NOW

https://t.co/4OT8fqf6lo

[Dr. Thomas Ichim @exosome]

A pedometer for brain health

I’m getting one !!

https://t.co/F6ksnH5dN3

[Immorta Bio @ImmortaBio]

Immorta Bio is well aware that extra time is only valuable when it is lived, not merely survived. The goal is not immortality, but to remain fully oneself for as long as life allows. Learn more at https://t.co/gW2OTIRK8r.

#immortabio #immortality #biotech #livelonger

[Ridge & Frost @RidgeandFrost]

Can research into cell death help to extend life?

@SophyRidgeSky and @WilfredFrost have spoken to two sisters Dr Carina Kern and Serena Kern-Libera, the founders of LinkGevity. They are working on human trials into cell death to crack the code to a longer life.

📺 Sky 501

[Dr Carina Kern @CarinaCarlaKern]

As 2025 comes to a close, I’m proud of what we’ve accomplished at @LinkGevity and what’s possible when you challenge orthodoxy. This year, welcoming my nephew made the “why” even clearer.
Onwards to 2026! 🚀 #longevity #aging #ageing #necrosis