Ira Espuny-Camacho

Stem Cell Biologist driven by interest in development, disease and aging

[Ira Espuny-Camacho @ira_espuny]

Draw the red line for Gaza, next Sunday 7th of September 14:00h in Brussels. Stop the non-sense humanitarian crimes and the silence from the International community.

[Ira Espuny-Camacho @ira_espuny]

Finally accepted in Stem Cells! Our work shows the effect of SARS-CoV2 infection in the brain using human brain organoids.

SARS-CoV2 infection triggers inflammatory conditions and astrogliosis-related gene expression in long-term human cortical organoids https://t.co/XAqobDN4jL

[stopbarreresBCN♿ @StopbarrerasBCN]

Vota a Decidim Barcelona per aconseguir unes platges veritablement accessibles. Data límit dissabte 17 de maig. Màxima difusió!
https://t.co/qGbIjt9ZD5

[Ira Espuny-Camacho @ira_espuny]

‘Big leap’ for Parkinson’s treatment: symptoms improve in stem-cell trials https://t.co/ale7yzF2aI

[Ira Espuny-Camacho @ira_espuny]

Glad to have participated in this great work from my former lab in Italy on stem cell models to study HD: Huntington’s disease cellular phenotypes are rescued non-cell autonomously by healthy cells in mosaic telencephalic organoids | Nature Communications https://t.co/32Rpnk3qgT

[Ira Espuny-Camacho @ira_espuny]

The first pre-print of my team is out. In collaboration with Laurent Nguyen, Jean-Claude Twizere and Emmanuel di Valentin: SARS-CoV2 infection triggers reactive astrocyte states and inflammatory conditions in long-term Human Cortical Organoids | bioRxiv https://t.co/F9RTWEMvZb

[nature @Nature]

AI that reads brain scans shows promise for finding Alzheimer’s genes https://t.co/D0u92NS0Uk

[Ira Espuny-Camacho @ira_espuny]

Is CRISPR safe? Genome editing gets its first FDA scrutiny https://t.co/mkz8iKRShj

[ZhiSong He 何志嵩 @zhisong_he]

Here comes the tweetorial of our recent work in the preprint https://t.co/T6DCMKbAT7, where we present first draft of human neural organoid cell atlas HNOCA, by integrating 1.8 million cells from scRNA-seq data sets representing 26 different neural #Organoids protocols

[Sergiu P. Pasca @Sergiu_P_Pasca]

There are now hundreds of genes associated with autism & neurodevelopmental disorders but what
key processes in brain development they each disrupt remains unknown.

In an article in @Nature today, we start tackling this question by combining forebrain #assembloids with CRISPR screens to map >400 disease genes onto stages of human cortical interneuron development.

Using engineered lines, regionalized neural #organoids and over 1,000
#assembloids, we discovered a group of disease genes that interfere with GABAergic neuron generation or migration, including some surprising disease mechanisms. Check out the video below for details.

This work was led by the fearless @XianglingM in the lab!!
In collaboration with Bassik lab & @panagiog lab!

Article here: https://t.co/hAKHSEGjVv

Supported by the @BrOrganogenesis @StanfordBrain @StanfordBioX @nyscf @cziscience

[Ira Espuny-Camacho @ira_espuny]

MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer’s disease | Science https://t.co/auacVSzWqK

[Ira Espuny-Camacho @ira_espuny]

Platelet factors attenuate inflammation and rescue cognition in ageing | Nature https://t.co/ksVzR99gmm

[Ira Espuny-Camacho @ira_espuny]

Older mouse brains rejuvenated by protein found in young blood https://t.co/Wds9Fyd8nH

[Ira Espuny-Camacho @ira_espuny]

Young glial progenitor cells competitively replace aged and diseased human glia in the adult chimeric mouse brain | Nature Biotechnology https://t.co/qxJoeIPll1

[Ira Espuny-Camacho @ira_espuny]

Gut microbiome composition may be an indicator of preclinical Alzheimer’s disease | Science Translational Medicine https://t.co/WYBi17tHc9

[Ira Espuny-Camacho @ira_espuny]

Proteomics analysis of plasma from middle-aged adults identifies protein markers of dementia risk in later life | Science Translational Medicine https://t.co/9vN0pDF3zj

[Ira Espuny-Camacho @ira_espuny]

Most advanced synthetic human embryos yet spark controversy https://t.co/ZJKwV9IxeL

[Ira Espuny-Camacho @ira_espuny]

Alzheimer’s drug donanemab: what promising trial means for treatments https://t.co/spFrDz5lAS

[Sandra Acosta @sacostav]

Do you want to apply for a Marie Curie fellowship, to do a postdoc in a cool lab in Barcelona. Join us, I’m recruiting a Marie Curie candidate! We have quite cool to work with brain organoids and the neurodev enhancerome in the lab waiting for you! Look how cool we are

[Ali H. Shaib @AliHShaib]

Hello world, ONE is here... I am happy to share with you a new technology —termed #ONE_Microscopy, that allows a resolution approaching ~8 Å using conventional light microscopy.
@LabSauer @eboyden3 @RaduAricescu
Full story:
https://t.co/uxUZTUZeYl