Pragati Muthukumar

PhD Candidate in Chemical Biomolecular Engineering at University of Delaware|| MIT ‘23 ChemE ||#synbio#rulez 🔥🥼🧬

[Pragati Muthukumar @itag_45]

@CW18isDaGOAT @goballoutski @hyattwatcher This is funny

[Shicheng Guo @ShihchengGuo]

Discover a bioengineering breakthrough: a novel synthetic protein degradation circuit using Sortase A for precise control, enhancing BioPROTACs beyond traditional roles! 🧬✨ PMID:41027936, Nat Commun 2025, @NatureComms https://t.co/hrQv124hnO #AI #Pharma #BioMed #RNA #ASHG #ESHG

[CNN Breaking News @cnnbrk]

Supreme Court won't overturn its landmark precedent recognizing a constitutional right to same-sex marriage. https://t.co/sZg0Rw9a2d

[Katie Galloway @GallowayLabMIT]

🤔How do you design a promoter for stable titration of expression?
💡Try programmable promoter editing with DIAL!
📰Now published at @NatureBiotech 🧵 [1/n]
🔗 below

[Pragati Muthukumar @itag_45]

@GallowayLabMIT @NatureBiotech @MITChemE @kochinstitute @MITdeptofBE @science_sneha @yunbeenbae @kaseyslove @DeonPloessl Incredible work Professor Galloway!!!

[Pragati Muthukumar @itag_45]

Thank you @hoppen1 for leading this impactful work @WilfredChen1 for being such a wonderful and supportive advisor.

[Pragati Muthukumar @itag_45]

BioPROTACs are proteins designed for targeted protein degradation(TPD) Here, we demonstrate the first major application of Sortase A cleavage & ligation as a control mechanism for synthetic circuitry to control TPD in a mammalian cell system.

https://t.co/A7WGwISsFS

[Pragati Muthukumar @itag_45]

Does every engineered cell we deploy into the environment or human body need to have a kill switch?

[Pragati Muthukumar @itag_45]

@kunjapur True but they are having a historic run and I love myself a good sports underdog story 👌🏽👌🏽

[Pragati Muthukumar @itag_45]

I can’t wait for the NBA finals game 7. I am obsessed especially with this unexpected pacers run

[Jake Wintermute 🧬/acc @SynBio1]

Many scientists are proud of their craft and the highly specialized skills they hone at the bench

But nobody hates Western Blots more than the people who have to do them

[Karly Kingsley @karlykingsley]

When Roe was overturned and women bled out in ERs, we heard “states’ rights. When guns became the #1 killer of kids, still “states’ rights.” But one protest against injustice? Suddenly there’s federal boots on the ground. They don’t panic when people die, only when they speak.

[Katie Galloway @GallowayLabMIT]

Today at @CellSystemsCP we report in back-to-back papers (!) led by @nbwang22 on how cell state potentiates the influence of individual transcription factors to drive cell-fate programming
&
how we used these insights to scale up production of motor neurons from primary fibroblasts, allowing us to deliver these directly converted neurons into the brains of mice.

Updated tweetorial coming soon (links below!)

[Pragati Muthukumar @itag_45]

Science Advances posted a collection of articles covering key scientific discoveries around women’s health. https://t.co/qrFYmbdesY
#womenhealth #Science #discovery

[Pragati Muthukumar @itag_45]

#wwenewark

[ISRO @isro]

Chandrayaan-3 Mission update:
The spacecraft's health is normal.

The first orbit-raising maneuver (Earthbound firing-1) is successfully performed at ISTRAC/ISRO, Bengaluru.

Spacecraft is now in 41762 km x 173 km orbit.

[Pragati Muthukumar @itag_45]

Posting these trip! Grad trip in tulum MX❤️🌴👸🏽🌴

[Pragati Muthukumar @itag_45]

I am so beyond grateful to have been apart of @GallowayLabMIT as an undergraduate UROP student since my Sophomore year!!! I couldn’t have asked for a more supportive and intellectually stimulating lab environment! Thank you Professor Galloway and Chris Johnstone!

[Pragati Muthukumar @itag_45]

@bbha_77 HAHAHA

[Massachusetts Institute of Technology (MIT) @MIT]

Congratulations, Class of #MIT2023! 👏