Ivo Veletic, MD

Translational heme/onc scientist | spatial biology • biomarkers • precision medicine | Leukemia & MPNs

[Ivo Veletic, MD @iveletic]

Our #Opal bone marrow image is featured on the new @BloodPortfolio cover, highlighting the discovery of OSMR as a novel #AML biomarker. This work was led by @HusseinAbbasLab, @patrickreville, @BofeiWang3 and @JenMarvinPeek at @MDAndersonNews. Learn more: https://t.co/VzHz9edftU

[Ivo Veletic, MD @iveletic]

Pleased to share our new study led by @HusseinAbbasLab, just published in @Nature_NPJ Precision Oncology! We reveal the presence of tertiary lymphoid-like structures (TLS) in the bone marrow of #AML patients using high-plex #SpatialProteomics. Learn more: https://t.co/zdQODnpT6j

[Ivo Veletic, MD @iveletic]

Excited to share our new paper out today in @LeukemiaJnl! CLL cell-derived #exosomes disrupt immune and hematopoietic systems – reprogramming immune cells, suppressing hematopoiesis, and driving disease. Read full article: https://t.co/62O0TrxLSB
@MDAndersonNews #CLL #leusm

[Ivo Veletic, MD @iveletic]

Great poster session on the temporal dynamics of bone marrow fibrocytes in primary #myelofibrosis at #ASH24 #MPNSM! Enjoyed the insightful discussions with @doctorpemm @MDAndersonNews. Learn more: https://t.co/xZCylIQ81T

[Ivo Veletic, MD @iveletic]

A second paper out on the same day! Also happy to share our @J_Immunol study in #CLL cells. This work shows how constitutively activated #STAT3 induces the expression of #PTX3, a key promotor of #fibrocyte differentiation. Link 👇
https://t.co/AC9N5UdaQ6
@MDAndersonNews #leusm

[Ivo Veletic, MD @iveletic]

Proud to share our latest work on #myelofibrosis #fibrocytes and the role #GLI1 plays in survival and dysfunction of these monocyte-derived cells. Could targeting STAT3-GLI1 axis alleviate BM fibrosis in MF? Full paper: https://t.co/ElTYMKGb0i
@cddpress @MDAndersonNews #MPNSM

[Ivo Veletic, MD @iveletic]

#ASH19: STAT3-induced Gli1 promotes #fibrocyte differentiation in MF. Join us at poster booth # 2961 Abstract: https://t.co/m8Yepbnhmi @LeukemiaMDA #MPN

[Ivo Veletic, MD @iveletic]

We are competing for the Blood cover of the year! Vote for our cover here: https://t.co/sPnjfsszqq @LeukemiaMDA @MDAndersonNews #ASH19 #MPN

[Blood Journals Portfolio @BloodPortfolio]

Blood’s annual Cover Art Contest is now underway! Make sure to cast your vote https://t.co/mYgWiLUewO

[Ivo Veletic, MD @iveletic]

Our new paper just out: Neoplastic #monocytes induce #myelofibrosis-like phenotype in immunodeficient mice and give rise to #megakaryocyte progenitor cells | #mpnsm @PLOSONE @LeukemiaMDA

https://t.co/FznJz7TN4M

[Blood Journals Portfolio @BloodPortfolio]

On this cover JAK2 is phosphorylated in tartrate-resistant acid phosphatase/cathepsin K –positive osteoclasts located along sclerotic bone trabecula of a myelofibrosis patient with a JAK2V617F mutation. https://t.co/rrZteE9HX1

[Blood Journals Portfolio @BloodPortfolio]

Cover article: Myelofibrosis osteoclasts are clonal and functionally impaired https://t.co/dYQnmii7lg

[Ivo Veletic, MD @iveletic]

Our team's work on clonal and dysfunctional #osteoclasts in #myelofibrosis is featured on the cover of the new issue of @BloodJournal | https://t.co/nJA9SVmRTW | #mpnsm @LeukemiaMDA @MDAndersonNews

[Blood Journals Portfolio @BloodPortfolio]

Check out this week’s issue of Blood: https://t.co/eInmSzLMKO #hematology

[Ivo Veletic, MD @iveletic]

#ASH18 MPN oral clinical | Dr Srdan Verstovsek @LeukemiaMDA presenting our group's first results with pentraxin analogue PRM-151 in #myelofibrosis pts, incl. promising reduction in BM #fibrocyte counts and #fibrosis levels | https://t.co/yvyQBivgms #MPNsm

[Ivo Veletic, MD @iveletic]

Check out our #ASH18 poster on the role of #Gli1+ BM #fibrocytes in #myelofibrosis (Abstract 1793: https://t.co/1K1SaiGUlX) #MPN @LeukemiaMDA

[Ivo Veletic, MD @iveletic]

Couple of treatment key points from @LeukemiaMDA meeting currently taking place in #Croatia

[MDedge Hematology & Oncology @MDedgeHemOnc]

Srdan Verstovsek's tips on using #ruxolitinib in #myelofibrosis #LeukLymph2018 #Dubrovnik #MPN

[Ivo Veletic, MD @iveletic]

This year's #NobelPrize goes to Dr. Allison at our institution for the discovery of new generation of #immunotherapy @LeukemiaMDA @MDAndersonNews

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The 2018 #NobelPrize in Physiology or Medicine has been awarded jointly to James P. Allison and Tasuku Honjo “for their discovery of cancer therapy by inhibition of negative immune regulation.”

[Naveen Pemmaraju, MD @doctorpemm]

#MPNSM = Myeloproliferative Neoplasms on Social Media | follow the discussions in field of MPN on Twitter at #MPNSM | @AaronGerds @mtmdphd @Vikas_Gupta_1 @mpdrc @jjkiladjian @andrewschorr @PatientPower @VJHemOnc @MPN_RF @mpnadvocacy @LeukemiaMDA @lauracmichaelis @BldCancerDoc

[Ivo Veletic, MD @iveletic]

Our group's latest report underlines the relevance of targeting neoplastic #monocytes in #myelofibrosis @LeukemiaMDA #mpn https://t.co/RiJ1q8RDFg