James Wise

Partner @Balderton. Investing in AI, health and energy. Chair of UK Sovereign AI. Author Start-Up Century. Mostly Generative.

[James Wise @Jameswise]

@NanneWielinga @rexsalisbury Bingo

[James Wise @Jameswise]

@mlejva @e2b Incredible - congrats team @e2b!

[James Wise @Jameswise]

@Samuelwego @balderton https://t.co/oLgjJlK3Yk

[James Wise @Jameswise]

Do you know what you need? MORE CONTENT FROM VENTURE CAPITAL FIRMS!

We're launching Series 3 of What's Next, @balderton's interview series with founders and researchers working at the frontier of new technologies. In this series we cover everything from agentic security to AI in chip design, industry, science and defence - hearing from the people shaping these sectors.

Our first episode goes live next week with Hanah-Marie Darley, where we discuss her career in Government Intelligence across the Atlantic, her time at Darktrace and founding the breakout cyber-security firm Geordie, and how they secure agents for some of the biggest companies in the world. Subscribe here, on YouTube or your usual podcast channels.

[James Wise @Jameswise]

I'm a huge fan of @DanNeidle so no shade here, but 'somewhere between psychic and insane' is precisely how many founders would describe themselves.....

[Peston @itvpeston]

‘They’d have to be somewhere between psychic and insane’

Tax Expert @DanNeidle says he’s sceptical about the founder’s relief scheme announced in the budget

#Peston

[James Wise @Jameswise]

Since we launched SovAI 6 months ago, we have invested in over a dozen British AI companies, designed and launched a unique procurement scheme to make Government a better customer - with over 100 companies now in that process - and have supported entrepreneurs voices in Govt on everything from non-competes to essential data access.

It’s great to have an additional 25% funding to expand our areas of focus to include industrial applications of AI, and buy more services from British start-ups in particular in cyber security.

Here’s to an even bigger next 6 months - so much more to do.

[Sovereign AI @UKSovereignAI]

We’re excited to announce an additional £120m for Sovereign AI to back the future of AI in Britain.

An extra £60m to invest in the UK’s most promising AI companies, expanding into Physical and Industrial AI.

And £60m more for R&D procurement, backing innovation in areas such as AI security and AI for healthcare.

We want to help founders start and scale in Britain, and turn innovation into impact.

[Fuse Energy @fuseenergy]

Fuse Energy is entering AI compute.

Introducing Fuse Compute: dedicated NVIDIA GPUs in UK data centres hosted and powered by Fuse. Available to businesses globally.

Sensitive customer data needs a clear answer to where it runs and who it runs next to.

With Fuse Compute, it’s bare-metal GPU nodes reserved for you alone, hosted in the UK, under UK jurisdiction.

The hardest part of scaling compute today is getting power to the site, which is the part we already do. With 142MW of data centre connections in the pipeline across 15 projects, compute is our next step. We have the infrastructure to deliver this to businesses globally.

Our first 128 NVIDIA GPUs are due online in December 2026, followed by 1,024 in Q2 2027.

Reserve your capacity now.

[James Wise @Jameswise]

@texhnogatsby Security is one of the five core investment themes, and half of the current SovAI procurement challenges are on security solutions. All at https://t.co/LThLIb8ZE5.

[James Wise @Jameswise]

If it wasn’t obvious already we’re in a completely new paradigm of cyber vulnerabilities.

Product teams at Cloudflare, Mozilla, Chrome, Safari etc are doing incredible work keeping up - but wow we need more and better defensive cyber models to harden applications and the web yesterday.

It is astonishing to read in the @thetimes today an Op-Ed from @parismarx saying AI hasn’t changed anything! Head in the sand is not a strategic option.

[Cloudflare @Cloudflare]

Following the discovery that eight eMudhra intermediate certificates use weak keys, Cloudflare is deploying mitigations and releasing client updates. We explain the impact, our response, and what customers and developers should do next. https://t.co/lYGxHb3PHS

[James Wise @Jameswise]

@AxleLandt It can get better

[NCSC UK @NCSC]

The NCSC is encouraging UK organisations to prepare for immediate updating of systems using PHP. Where immediate remediation is not feasible, organisations should consider taking the system offline until it can be fully mitigated.

For more⬇️
https://t.co/l6TDtVurJN

[James Wise @Jameswise]

@Jaw9c Nice to know I haven't been overtaken by the frontier on posts yet...

[James Wise @Jameswise]

Now that we've cracked Navier-Stokes and flying cars, there is only one true, super-human technological challenge left - lowering British electricity bills.

And Fuse seem to have cracked it! An affordable home battery & solar system which means lower bills and more energy independence at home, and at scale more capacity on the grid.

Hi there Jules, another impressive release from @alanchanguk , @charlesorr and the phenomenal team @fuseenergy.

[Fuse Energy @fuseenergy]

Meet Jules by Fuse Energy.

An intelligent energy system for your home. Plug in and autopilot does the rest.

It learns your habits, stores power, trades the excess and continuously lowers your bills.

Solar and storage is now for everyone.
Energy intelligently designed for you.

Up to £330 a year off your bills.
Reservations now open

[James Wise @Jameswise]

@vinousali @thomasforth Stopping Tom getting scammed is a national security priority.

[Sovereign AI @UKSovereignAI]

We’re delighted to announce our investment in Augur.

Augur is building technology that can help security teams find information faster and respond sooner, with applications across public safety, serious crime and critical infrastructure.

Augur is already working on capability to prevent attacks by hostile states on Britain’s critical national infrastructure. They’re also partnering with @TfL to help identify and detect sexual offending on the transport network, behaviours that disproportionally impact women and girls.

We’re excited about the potential to help keep people safer, give investigators valuable time back, and spot threats before they become more serious. The Augur team is tackling an incredibly important problem and building the solution here in Britain.

Read our blog below for more information on Augur’s technology.

[Ole Lehmann @itsolelehmann]

“okay, so what? it’s just math.”

no, you don't get it.

here’s what OpenAI’s math breakthroughs could eventually help make possible in the real world:

Vlasov–Maxwell → stronger foundations for fusion research, whose ultimate prize is virtually limitless clean energy to power civilization

Calderón’s Problem → portable body scanners using electrical signals, making medical imaging cheaper and easier to access

Maximum-Cardinality Matching → faster searches for compatible kidney swaps across large donor pools, helping hospitals coordinate lifesaving transplants

Inverse Elasticity Problem → scans that map tissue stiffness, helping doctors locate suspicious growths inside the body

Mumford–Shah Conjecture → better tools for spotting tissue changes in brain scans, helping doctors identify signs of disease

Bose–Einstein Condensation → stronger foundations for quantum sensors that could help vehicles navigate without GPS

Simple Stochastic Games → better safety checks for self-driving cars and robots before dangerous mistakes reach the real world

Matrix Multiplication → cheaper AI and bigger scientific simulations using the same computers

Edit Distance → faster DNA comparisons, helping researchers study genetic changes linked to disease

The k-Server Problem → robots that waste less movement and energy, making warehouses more efficient and goods cheaper to move

a reminder that math is the foundation of science.

so accelerating mathematical discovery could compress centuries of scientific progress into years.

insane timeline to be alive for!