Jan-Hannes Schäfer

Archive only. Find me where the sky is blue for more:

[Jan-Hannes Schäfer @jhschaef]

@AlanRoseman3 We have the solution. Thanks!

[Jan-Hannes Schäfer @jhschaef]

@RuetterM Thanks. You are right, they look very similar. We might have solved it. I'll keep you updated. Let's see what ModelAngelo thinks... If there is high resolution.

[Jan-Hannes Schäfer @jhschaef]

Our Structure of the yeast Ceramide Synthase is now out @NatureSMB! Thanks to all involved from @FlorianFrhlich3 and @MoellerGroup. https://t.co/f8pkmatxpK #cryoEM #uos

[Jan-Hannes Schäfer @jhschaef]

Preprint Alert! 📣We've solved the first structure of a Ceramide Synthase.
Great Team work @FlorianFrhlich3 @MoellerGroup @DJanuliene @UniOsnabrueck
Thanks to co-first Lena Clausmeyer & Carolin Körner! #uos #cryoEM #openscience https://t.co/gseUwP6vsg

[Jan-Hannes Schäfer @jhschaef]

Happy to see another chapter of my PhD work on yeast SPT-Orm2 out at @CellReports. Thanks to all involved! https://t.co/ZEcWwW0qlG #lipidtime #cryoEM

[Jan-Hannes Schäfer @jhschaef]

Our #lipidtime story continues with yeast SPT-Orm2! Great team-work with co-first Carolin Körner from @FlorianFrhlich3. @MoellerGroup @DJanuliene @krparey and @teislab Oliver Schmidt. #b3d #cryoEM Have a look https://t.co/6Zn74nC0Jr

[Jan-Hannes Schäfer @jhschaef]

@sonjawelsch @MoellerGroup @DJanuliene @UniOsnabrueck @seegerlab @FlorianFrhlich3 Thanks @sonjawelsch

[Jan-Hannes Schäfer @jhschaef]

Happy to have contributed to solving Gaucher's disease GCase-LIMP-2 complex. Congrats to first Jan Philipp Dobert from Zunke-lab & Arnold-lab and all others. @MoellerGroup @Molecular_Neuro https://t.co/CKrbgQ7sKG #b3d #cryoEM

[Jan-Hannes Schäfer @jhschaef]

Our #lipidtime story continues with yeast SPT-Orm2! Great team-work with co-first Carolin Körner from @FlorianFrhlich3. @MoellerGroup @DJanuliene @krparey and @teislab Oliver Schmidt. #b3d #cryoEM Have a look https://t.co/6Zn74nC0Jr

[Jan-Hannes Schäfer @jhschaef]

@sonjawelsch @MoellerGroup Next time for shure. 😂

[Jan-Hannes Schäfer @jhschaef]

Update: Congrats to @DavidBSauer and team for solving human CerS6 https://t.co/b72IffpJG4 - Who knew, its a "ping-pong" mechanism!

[Jan-Hannes Schäfer @jhschaef]

Preprint Alert! 📣We've solved the first structure of a Ceramide Synthase.
Great Team work @FlorianFrhlich3 @MoellerGroup @DJanuliene @UniOsnabrueck
Thanks to co-first Lena Clausmeyer & Carolin Körner! #uos #cryoEM #openscience https://t.co/gseUwP6vsg

[Jan-Hannes Schäfer @jhschaef]

Update: Nice work from Xin Gong on homo-dimer of yeast CerS on EMBO https://t.co/ejXp79HPKo

[Jan-Hannes Schäfer @jhschaef]

@DavidBSauer @TomasPascoa @CmdOxford @Boehringer @BoehringerDE @UZH_en @DavidBSauer Would you be willing to add the Supplementary Material to bioRxiv too? Allways curious to see the full processing workflow.

[Jan-Hannes Schäfer @jhschaef]

@DavidBSauer @TomasPascoa @CmdOxford @Boehringer @BoehringerDE @UZH_en @DavidBSauer Congrats to all involved! This aligns with our findings from yeast Ceramide Synthase https://t.co/gseUwP6vsg

[Jan-Hannes Schäfer @jhschaef]

@vicsnorr @IevaDrulyte @FlorianFrhlich3 @MoellerGroup @DJanuliene @UniOsnabrueck Thanks Victor. Highly recommend Blender and #MolecularNodes from @bradyajohnston

[Jan-Hannes Schäfer @jhschaef]

@vicsnorr @_Murphy_Lab Congratulations 🎉 Very nice story!

[Jan-Hannes Schäfer @jhschaef]

@alebarbieri87 @MoellerGroup @NatureComms @FlorianFrhlich3 I've used Blender with Molecular Nodes from @bradyajohnston

[Jan-Hannes Schäfer @jhschaef]

Our paper on "Structure of the ceramide-bound SPOTS complex" is now out in @NatureComms - Fantastic teamwork with co-first Carolin Körner from @FlorianFrhlich3 https://t.co/0w3P5BqnyL @MoellerGroup #CryoEM #UOS 🔬❄️

[Jan-Hannes Schäfer @jhschaef]

@sonjawelsch @DJanuliene @NatureComms @FlorianFrhlich3 @MoellerGroup Thanks @sonjawelsch - Revisiting seemingly bad 3D classes got us there. @DJanuliene was of great help all the way - a great mentor. CryoEM is always teamwork. Thanks @krparey for the #magic during model building!

[Jan-Hannes Schäfer @jhschaef]

The yeast SPOTS complex involves Sac1 🟣 and is bound to ceramide and ergosterol. Let's find out more about this cross-talk between the membrane code and protein activity.

[Jan-Hannes Schäfer @jhschaef]

@klausenhauser @MoellerGroup Thanks to @YongChan_zzz - have a look at his 🧵

[Jan-Hannes Schäfer @jhschaef]

That is a first for me on our Glacios. No ApoF. Friday #cryoEM goals unlocked 🍩 #uos @MoellerGroup