Jonathan Brown

Physician-scientist, fly-fisherman, family man, ice cream and live music enthusiast.

[Jonathan Brown @JonathanBrownMD]

@EricAdler17 @JCI_insight @VUMCResearch @Novartis Thanks Eric! A very rewarding collab with Novartis. Lots more to do now.

[Jonathan Brown @JonathanBrownMD]

Our new publication @JCI_insight. Tremendous collaboration with Robb Flynn @VUMCresearch and @Novartis. Integration of RNAseq, chromatin signaling and CRISPR screen reveals ZNF469 is a transcriptional regulator of #fibrosis in human #MASLD, #NAFLD https://t.co/XViTnp45g6

[Sarnoff Foundation @SarnoffCardio]

Sarnoff Members gather at Vanderbilt. Drs Scott Baldwin, Jonathan Brown and Arun Padmanabhan!

[𝙼𝚊𝚝𝚝 𝙻𝚞𝚝𝚑𝚎𝚛 @DrJMLuther]

Congratulations to @DrMonaMash on publishing her latest manuscript from our @American_Heart funded study!
@JLGamboa_Velez
@VUMCResearch
@vumcdiabetes

https://t.co/JyWS2mW8R7

[Jonathan Brown @JonathanBrownMD]

Amazing CV Research Day celebration @VUMC_heart with @alan_daugherty giving keynote address. Congrats @AzuahTheShort in @AmandaDoranLab for best student abstract. Record turnout to promote cardiovascular science @VUMCResearch.

[Jonathan Brown @JonathanBrownMD]

Outstanding CV grand rounds @VUMC_heart today from @AartiAsnaniMD on cardiac toxicities from chemotherapy and potential new therapeutic pathways. Beautiful and careful science. #VUMC #CardioOnc #HeartFailure

[Jonathan Brown @JonathanBrownMD]

Congrats to Ronan Bracken graduate student in @JonBrownLab. Advancing to PhD candidacy in @VandyBiochem. #donewithquals!!! 🙌🧬🧬🧬

[Jonathan Brown @JonathanBrownMD]

On clinical service now. This @statnews article really resonates. Easy to forget priorities in all the data and EHR. Be present with patients.https://t.co/EkPHhmpykP

[Jonathan Brown @JonathanBrownMD]

Fantastic seminar from Tony Rosenzweig @VUMCResearch @VUMC_heart at our weekly research seminar in CV medicine on impact of exercise in cardiac plasticity. Next time in person for sure!

[Anthony Rosenzweig, MD @rosenzweig_a]

@CardioOncology @JaneFreedmanMD @MGHHeartHealth @JenHoCardiology @pnatarajanmd @MarkELindsay @MGHMedicine @JJheart_doc @mchonig @TomasNeilan @JonathanBrownMD @JonBrownLabVUMC @VUMChealth @VUMC_heart Honored to join you all. Sorry it couldn’t be in person!

[Jonathan Brown @JonathanBrownMD]

Important study by Dan Clark et al @VUMC_heart on #COVID19 myocarditis in athletes. Not all LGE = myocarditis. Power of comparators in research! COVID-19 Myocardial Pathology Evaluation in AthleTEs with Cardiac Magnetic Resonance (COMPETE CMR) https://t.co/qnsxZZFuo8

[Jonathan Brown @JonathanBrownMD]

Congrats on this grant. Great team exploring how dysfunctional HDL drives vascular and kidney disease.

[Javid Moslehi @CardioOncology]

A big congrats to Mac Linton, Kasey Vickers and team at @VUMChealth @VUMC_heart on this PPG investigating HDL function in human disease! @KaseyVickers @JonBrownLabVUMC @AmandaDoranLab @JonathanBrownMD https://t.co/oYMjAjMNdU

[Jonathan Brown @JonathanBrownMD]

Interesting read in @WSJ about role of managers in business. But, ideas clearly relevant to organizing a research lab. Managers (change to PI) as "coaches" and not authority figures. https://t.co/IxmbKJvCEL

[Jonathan Brown @JonathanBrownMD]

Read this study from Paul Cohen @RockefellerUniv about Brown Fat in humans and risk of cardiometabolic disease. Nice to see independent work from former @BrighamFellows. https://t.co/ATScpg7Zqx

[The Scientist @TheScientistLLC]

These associations are raising the really exciting notion that perhaps the presence of brown fat protects against these obesity-associated diseases. —Paul Cohen, the Rockefeller University / @RockefellerUniv https://t.co/qiD6PbvzKo

[Nature Reviews Drug Discovery @NatRevDrugDisc]

In vivo base editing shows promise in treating the genetic accelerated-aging disorder Hutchinson–Gilford progeria syndrome in mice - find out more in our latest highlight of research by @jonbrownlabVUMC
@davidrliu @LiuGroup et al. https://t.co/hvQBfHResT

[Jonathan Brown @JonathanBrownMD]

@VerveTx announces one-time treatment with DNA base editor lowers cholesterol in sustained manner over 6 months in non-human primates. A bold therapeutic concept for #heartdisease in #HeFH. https://t.co/uKL4Cse1dz

[Jonathan Brown @JonathanBrownMD]

Check out this nice synopsis of our work on adenine base editor to treat #progeria @NIHDirector @davidrliu @LukeKoblan @mrrerdos @Progeria . Thanks to @broadinstitute for putting this together.

[Broad Institute @broadinstitute]

In a new Broad video, @NIHDirector, Jonathan Brown (@VUMChealth), and @davidrliu describe the impact of their recent work on treating #progeria in an animal model -- a story that began thirty-six years ago. Watch: https://t.co/vqXgJWvY0Q

[Jonathan Brown @JonathanBrownMD]

#PfizerVaccine dose #2. Feels like we are closing in on an end to #Covid_19. TGIV! Great way to end the week on a positive note. Proud to be part of @VUMChealth @VUMC_heart rollout. We can beat this!

[Jonathan Brown @JonathanBrownMD]

@pnatarajanmd Thanks Pradeep. We’ve come a long way from VA CCU! Glad to see things are well for you too.

[Jonathan Brown @JonathanBrownMD]

So proud of this work demonstrating DNA base editing treatment for #progeria in human cells & mouse model. Amazing collaborative team @davidrliu @NIHDirector @LukeKoblan & Mike Erdos at NIH and my @VUMCResearch team @lindsaymdavison & Sean Doherty
https://t.co/6MN8Nq4gxt