Great to share this work with @YuSugiharaY 🚀
Come chat with us at #PPATH2026 about finding crop-native single-gene NLRs 🌾, AlphaFold 3 🤖, and bioengineering made-to-order plant immunity 🎯🛡️
One gene. No helper needed. 🌱🧬
We used AlphaFold 3 to discover single-gene NLR immune receptors in grasses 🌾 — then bioengineered SOLO1 to recognise a new target 🎯. #ECPP2026#PPATH2026
📌 Poster below
🔗 https://t.co/m5rwKo7yHa
So proud to see this story finally out!🎉 We added new data since our previous preprint—transgenic barley plants with an engineered immune receptor that fights off two fungal pathogens at once. Short 🧵and link to the original preprint thread👇
https://t.co/e0SrTwBMvc
Check out our latest work! AlphaFold 3 revealed a transient immune receptor complex that eluded biochemical studies for almost a decade🤯 We describe a conserved structural logic underlying sensor–helper communication in an NLR immune receptor network 🧵👇
https://t.co/H55EMmrtZn
Protein structure prediction changed biology. Protein assembly discovery is next.
We present SNI (Structural Novelty Index), a scalable framework for finding new protein complexes.
We used it to uncover an unexpected resistosome assembly: 11-mer. 🧵👇🏻
https://t.co/bCADVEnE6b
AI-guided discovery of atypical protein assemblies https://t.co/jFSl0e6Zps
So far, we’ve seen 5-mers, 6-mers, & 8-mers, but now it’s an 11-mer! A cool surprise from the NRC network on resistosome organization. Congrats to @amiralito_ Ben @daniel_luedke & the @KamounLab 👏✨💐
We are happy to celebrate @mpcontreras4 winning the @BiochemSoc 2027 Early Career Research Award!
Mauricio joined TSL as a predoc in the @kamounlab, where he did his PhD and postdoc before starting his own group at @ZMBP_Tuebingen.
Congrats Mau! 🏆
https://t.co/xQwN0XIWDp
It’s that time of year! #SchoBozKa in Downing College, Cambridge 🇬🇧
Running strong since 2017–Annual lab meeting of the teams of Sebastian Schornack, Tolga Bozkurt, Lida Derevnina, Phil Carella, Jiorgos Kourelis and Sophien Kamoun.
This year’s guest is Steven Spoel, University of Edinburgh
New Year Lunch 2026 @KamounLab
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