Check out our most recent work published on @jbiolchem
Biased GPCR signaling by the native parathyroid hormone-related protein 1–141 relative to its N-terminal fragment 1–36 https://t.co/f8UbetxARc
Researchers have discovered that spatial context determines how cells respond to parathyroid hormone—a finding that could potentially aid in the design of new and more precisely targeted drugs. https://t.co/LbKicdjyro @SciSignal#Biochemistry
Researchers have discovered that spatial bias in cells can influence biological outcomes from parathyroid hormone – a finding that could facilitate the design of new and more precisely targeted drugs. @PittDeptofMed#GPCRSignaling#MechanismMatters https://t.co/mR6J4fDKjF
By comparing responses to #ParathyroidHormone and a synthetic derivative in mice, the Vilardaga and Chang labs show the hormone’s effects on bone growth and serum vitamin D and calcium depend on the intracellular location of #cAMPsignaling. @PittDeptofMed https://t.co/XeUxIrlpa5
The new issue of Science Signaling has arrived! New research shows how spatial cues shape how cells respond to an essential vitamin D-regulating hormone, and explores prostaglandin E2 signaling in T cells. https://t.co/WrwwEyfCm7
The June 2021 issue of The Pharmacologist is now available! Read our feature article on poisons, our EB 2021 recap, and learn more about our recent bylaws revisions: https://t.co/xdOnlISW7l
Check out my poster at #EB2021
Location Bias in cAMP Signaling and its effects on Parathyroid Hormone Receptor Biological Effectiveness #ExpBio https://t.co/3t9oL0QRpM