John Keane

Consultant Urologist University Hospital Waterford and UPMC Aut Even

[NEJM @NEJM]

In cisplatin-ineligible patients with muscle-invasive bladder cancer, enfortumab vedotin–pembrolizumab plus surgery led to better event-free survival (74.7%, vs. 39.4%) and overall survival (79.7%, vs. 63.1%) than surgery alone at 2 years. Full phase 3 KEYNOTE-905 trial results and Research Summary: https://t.co/bzVbmJXHMD

[Yüksel Ürün @DrYukselUrun]

Bladder cancer is largely preventable.
Yet most patients hear about risk factors after diagnosis.
A short thread on what actually matters and what you can do now. 🧵

[UroToday.com @urotoday]

Extended vs limited pelvic lymph node dissection during radical prostatectomy for intermediate- and high-risk #ProstateCancer: 10 years of follow up - oncological outcomes from a randomized phase 3 trial. Presented by Matheus Ruggeri. #EAU26 written coverage by @zklaassen_md > https://t.co/hsySWX1P9K @Uroweb

[John Keane @keane_jpm]

@BBCSport Thank you @BBCSport

[John Keane @keane_jpm]

@BBCSport Thank you @BBCSport

[BBC Sport @BBCSport]

Ireland have now won as many Six Nations matches at Twickenham as the four other nations combined!

[NEJM @NEJM]

In cisplatin-ineligible patients with muscle-invasive bladder cancer, enfortumab vedotin–pembrolizumab plus surgery led to better event-free survival (74.7%, vs. 39.4%) and overall survival (79.7%, vs. 63.1%) than surgery alone at 2 years. Full phase 3 KEYNOTE-905/EV-303 trial results: https://t.co/6M3xhml0ou

Editorial: Enfortumab Vedotin plus Pembrolizumab as Perioperative Therapy https://t.co/3uNr9TUukQ

[Ray Boyne @AnalysisGaa]

EVADING THE HOOK
THEY WANT CONTACT
YOU WANT CONTROL

[John Keane @keane_jpm]

@Adam_Weiner535 @NEJM Thanks for your summaries of these major papers Adam

[Nikita Sushentsev @NikiSushentsev]

1/2 Just published in @JAMAOnc: 15-year outcomes of Active Monitoring, Surgery, and Radiotherapy for cribriform-positive and cribriform-negative prostate cancer in the ProtecT trial. Secondary analysis based on centralised biopsy review🔬 Article: https://t.co/qfCzYTmevN

[European Association of Urology (EAU) @Uroweb]

💊 Recurrent cystitis? Antibiotics aren’t always needed!

Women should know about evidence-based, antibiotic-sparing options like:
🔹 Xyloglucan + Hibiscus + Propolis
🔹 Centaurii herba, Levistici radix & Rosmarini folium

#WomensHealth #EAUGuidelines #UroUTI

[Toni Choueiri, MD @DrChoueiri]

JUST IN: Tar200 now @US_FDA approved based on SunRise-1 phase 2 trial in BCG unresponsive NMIBC.

-Intravesical form of Gemcitabine
- CR: 82.4%/grade ≥3 AE 12.9%
- DFS 70.2% at 12m
- 51% of CRs with DOR ≥ 12 months.

[Tekkers Foot @tekkersfoot]

🇭🇺✨ Dominik Szoboszlai’s free kick against Arsenal from this angle is incredible. 😍

[HSE Dublin and South East @HSEDubSouthEast]

On Friday, @HSELive published the 2023-2024 Annual Report for @UHW_Waterford South East Cancer Services, highlighting the continued focus on providing safe, high-quality care to patients in Waterford, Wexford, South Tipperary and Carlow/Kilkenny.

[UPMC Ireland @UPMCinIreland]

UPMC is proud to launch our upgraded PET CT scanner at UPMC Whitfield Hospital—offering faster access & enhanced diagnostic accuracy for patients across Waterford and the South East. Congratulations to our Radiology team for advancing care where it’s needed most.

[Andrew D. Huberman, Ph.D. @hubermanlab]

Very interesting study: disrupted gut microbiome in fibromyalgia (mouse & human data) supports the idea that improving gut microbe conditions may help. You can wait for more or just consume 1-3 servings low sugar fermented food daily per other findings https://t.co/6mTyU9wqvb

[Austen Allred @Austen]

Even if you’ve watched it 100 times already just watch it again

[The GAA @officialgaa]

🔥 GOAL 🔥

What a hit that is from Sean Kenneally 👌

#GAANOW #AllianzLeagues @TipperaryGAA

[European Urology Oncology @EurUrolOncol]

The Role of Baseline Prostate-specific Antigen Value Prior to Age 60 in Predicting Lethal Prostate Cancer: Analysis of a Contemporary North American Cohort by @FinatiMarco, Matthew Davis et al

https://t.co/RAfvMOTaf8

#UroSoMe #MedTwitter #ProstateCancer #PCa

[John Keane @keane_jpm]

@Crypto0637 AzXsV14rRsuxmdPfSb4ppybBaDREGcB82XWrCawbKNY1