Ken Hanscombe

[Mark Hamer @ma_hamer]

Convincing evidence for health benefits of #physicalactivity and #fitness @cathrynlewis @kenhanscombe @TheISEH @uk_biobank https://t.co/YlM0ahN492

[Ken Hanscombe @kenhanscombe]

8/ Thanks to all co-authors @PersynElodie @mtraylor_ @KylieGlanville @ma_hamer @Joni_Coleman @cathrynlewis, and the @uk_biobank participants

[Ken Hanscombe @kenhanscombe]

5/ Lots more results eg. genetic variation associated with greater CRF was associated with lower levels of glycoprotein acetyls (GlycA). Elevated blood concentrations of GlycA are a strong predictor for long-term risk of morbidity and mortality from a wide range of diseases

[Ken Hanscombe @kenhanscombe]

7/ Exercise is good for you. How much? See the European Society of Cardiology (ESC) @escardio https://t.co/7rDuDZtedk

[Dr Rani Khatib FESC @DrRaniKhatib]

Recommendations on Physical activity and exercise in the New ESC Guidelines on cardiovascular disease prevention.
#cardiotwitter #ESCCongress #ESCGuidelines

[Ken Hanscombe @kenhanscombe]

4/ These same genes have previously been associated with eg. CAD, diabetes, stroke, lung function, blood pressure, and BMI

[Ken Hanscombe @kenhanscombe]

1/ How important is exercise and fitness? What does genetics tell us about the links between cardiorespiratory fitness (CRF) and physical activity (PA), and health? Below are some highlights of our work on the genetics of CRF and PA in the @uk_biobank https://t.co/f5ELODso0x

[Ken Hanscombe @kenhanscombe]

3/ Genetic variants associated with CRF and PA also influenced genetic expression in a relatively small set of genes in the heart, artery, lung, skeletal muscle and adipose tissue

[Ken Hanscombe @kenhanscombe]

2/ CRF and PA are influenced by genetics. Genetic variants associated with lower CRF and PA were associated with poor health outcomes eg. increased risk for coronary artery disease (CAD), type 2 diabetes (including insulin resistance, fasting glucose), BMI, and a shorter lifespan

[Ken Hanscombe @kenhanscombe]

Plant-based milk is human milk. Dairy milk is baby calf growth fluid.

Dairy cows are artificially inseminated annually to keep up milk production. They often suffer painful engorgement… https://t.co/OZjpZu04rZ

[Ken Hanscombe @kenhanscombe]

Apocalypse it is, then. Not now, but probably next week | Marina Hyde https://t.co/vUR2LrhqPY

[Ken Hanscombe @kenhanscombe]

Petition: Revoke Article 50 and remain in the EU. https://t.co/96Xxz59pqB

[Ken Hanscombe @kenhanscombe]

A Python 3 wrapper for automated outlier removal using PLINK 2.0 --pca approx. Input: LD-pruned binary fileset.
https://t.co/OgP00dAFZE

[Ken Hanscombe @kenhanscombe]

@ofgem @ofgemmedia why is it still possible for @BritishGas to brazenly block customers trying to switch to another supplier, despite being fined £2.65m just last month, and £5.6m for the same unfair practice back in 2014? @BritishGas ref: 9002043301

[Ken Hanscombe @kenhanscombe]

Please suggest any #ukbtools functionality that you would find useful for querying genetic metadata, or more generally for analysing @uk_biobank data https://t.co/Binyynu3Qw

[Ken Hanscombe @kenhanscombe]

@uk_biobank changed how genetic metadata was served with the 500K release: as separate files instead of bundled with the general data download. See the #ukbtools note on genetic metadata, an also repeated variables. #rstats https://t.co/Binyynu3Qw

[Ken Hanscombe @kenhanscombe]

Plot LD Hub (ldsc) genetic correlation results, to compare across multiple categories #genomics #rstats #dataviz
https://t.co/iYWADJU1ch

[Ken Hanscombe @kenhanscombe]

SQL query genomic metadata (from UCSC) for genomic plots #SQL #rstats https://t.co/jdPmRD0aQW

[Conrad Hackett @conradhackett]

STATISTICS OF THE YEAR:
Americans killed annually by

All Islamic jihadist terrorists 9
Armed toddlers 21
Lightning 31
Lawnmowers 69
Being hit by a bus 264
Falling out of bed 737
Being shot by another American 11,737
https://t.co/OSAtlR8jnK

[Ken Hanscombe @kenhanscombe]

At the RFH. Classic.